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etnppl ethanolamine-phosphate phospho-lyase [ Danio rerio (zebrafish) ]

Gene ID: 393421, updated on 11-Apr-2024

Summary

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Official Symbol
etnpplprovided by ZNC
Official Full Name
ethanolamine-phosphate phospho-lyaseprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1133
See related
Ensembl:ENSDARG00000035544 AllianceGenome:ZFIN:ZDB-GENE-040426-1133
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
agxt2l1; zgc:63486
Summary
Predicted to enable ethanolamine-phosphate phospho-lyase activity; pyridoxal phosphate binding activity; and transaminase activity. Acts upstream of or within embryonic hemopoiesis. Predicted to be located in mitochondrion. Is expressed in intestinal bulb; liver; and yolk syncytial layer. Orthologous to human ETNPPL (ethanolamine-phosphate phospho-lyase). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 7
Exon count:
13
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (60079176..60090404)
105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (59774002..59785167)

Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene G protein-coupled receptor 78b Neighboring gene collagen type XXV alpha 1 chain Neighboring gene heat shock protein 12B Neighboring gene chaperonin containing TCP1, subunit 7 (eta)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Functional analysis of human hematopoietic stem cell gene expression using zebrafish. Eckfeldt CE, et al. PLoS Biol, 2005 Aug. PMID 16089502, Free PMC Article
  2. The Evolution of Duplicated Genes of the Cpi-17/Phi-1 (ppp1r14) Family of Protein Phosphatase 1 Inhibitors in Teleosts. Lang I, et al. Int J Mol Sci, 2020 Aug 9. PMID 32784920, Free PMC Article
  3. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Clone Names

  • MGC63486

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ethanolamine-phosphate phospho-lyase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ethanolamine-phosphate phospho-lyase activity IEA
Inferred from Electronic Annotation
more info
  
enables lyase activity IEA
Inferred from Electronic Annotation
more info
  
enables pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
  
enables transaminase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within embryonic hemopoiesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ethanolamine-phosphate phospho-lyase
Names
alanine--glyoxylate aminotransferase 2-like 1
NP_956743.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200449.1 → NP_956743.1  ethanolamine-phosphate phospho-lyase

    See identical proteins and their annotated locations for NP_956743.1

    Status: PROVISIONAL

    Source sequence(s)
    BC055122
    UniProtKB/Swiss-Prot
    Q7SY54
    Related
    ENSDARP00000051523.4, ENSDART00000051524.8
    Conserved Domains (2) summary
    cd00610
    Location:25 → 435
    OAT_like; Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase, ...
    COG0160
    Location:12 → 439
    GabT; 4-aminobutyrate aminotransferase or related aminotransferase [Amino acid transport and metabolism]

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007118.7 Reference GRCz11 Primary Assembly

    Range
    60079176..60090404
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_002459129.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7SY54.1 GenPept UniProtKB/Swiss-Prot:Q7SY54

Gene LinkOut

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