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    Mob2 [ Drosophila melanogaster ]

    Gene ID: 39293, updated on 10-May-2012
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    Summary

    Official Symbol
    Mob2provided by Flybase
    Primary source
    FLYBASE:FBgn0259481
    Locus tag
    Dmel_CG11711
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:GH13236; BEST:GH06341; CG11711; CG11712; Dmel\CG11711; Dmob1; dmob2; Dmob2; DMob2; gh06341; Mob1; MobI
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    Genomic context

    Location :
    68C12-68C13
    Sequence :
    Chromosome: 3L; NT_037436.3 (11515857..11555333, complement)
    See Mob2 in Epigenomics, MapViewer

    Chromosome 3L - NT_037436.3Genomic Context describing neighboring genes Neighboring gene CG7512 gene product from transcript CG7512-RC Neighboring gene CG11714 gene product from transcript CG11714-RA Neighboring gene alpha-L-fucosidase Neighboring gene mir-4968 stem loop Neighboring gene CG7394 gene product from transcript CG7394-RC Neighboring gene CG33267 gene product from transcript CG33267-RB

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Robust target gene discovery through transcriptome perturbations and genome-wide enhancer predictions in Drosophila uncovers a regulatory basis for sensory specification. Aerts S, et al. PLoS Biol, 2010 Jul 27. PMID 20668662.
    2. DMob4/Phocein regulates synapse formation, axonal transport, and microtubule organization. Schulte J, et al. J Neurosci, 2010 Apr 14. PMID 20392941.
    3. Function of Drosophila mob2 in photoreceptor morphogenesis. Liu LY, et al. Cell Tissue Res, 2009 Dec. PMID 19834743.
    4. Shared visual attention and memory systems in the Drosophila brain. van Swinderen B, et al. PLoS One, 2009 Jun 19. PMID 19543525.
    5. Sex-specific splicing in Drosophila: widespread occurrence, tissue specificity and evolutionary conservation. Telonis-Scott M, et al. Genetics, 2009 Feb. PMID 19015538.

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. An immunocytochemical study has shown that Mob2 is mainly localized in the apical membrane of photoreceptor cells during early development.
      Title: Function of Drosophila mob2 in photoreceptor morphogenesis.
    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:64660 BioGRID:65794 5-HT2    BioGRID  PubMed Two-hybrid 
    BioGRID:64660 BioGRID:58447 C901    BioGRID  PubMed Two-hybrid 
    BioGRID:64660 BioGRID:64134 CG10478    BioGRID  PubMed Two-hybrid 
    BioGRID:64660 BioGRID:64806 CG10948    BioGRID  PubMed Two-hybrid 
    BioGRID:64660 BioGRID:66688 CG11656    BioGRID  PubMed Two-hybrid 
    BioGRID:64660 BioGRID:64046 CG13711    BioGRID  PubMed Two-hybrid 
    BioGRID:64660 BioGRID:65947 CG15580    BioGRID  PubMed Two-hybrid 
    BioGRID:64660 BioGRID:60106 CG17377    BioGRID  PubMed Two-hybrid 
    BioGRID:64660 BioGRID:60564 CG31869    BioGRID  PubMed Two-hybrid 
    BioGRID:64660 BioGRID:72704 CG34168    BioGRID  PubMed Two-hybrid 
    BioGRID:64660 BioGRID:59654 CG3557    BioGRID  PubMed Two-hybrid 
    BioGRID:64660 BioGRID:72707 CG5693    BioGRID  PubMed Two-hybrid 
    BioGRID:64660 BioGRID:65477 CG6996    BioGRID  PubMed Two-hybrid 
    BioGRID:64660 BioGRID:58854 CG8128    BioGRID  PubMed Two-hybrid 
    BioGRID:64660 BioGRID:59987 CG9016    BioGRID  PubMed Two-hybrid 
    BioGRID:64660 BioGRID:59306 CG9572    BioGRID  PubMed Two-hybrid 
    BioGRID:64660 BioGRID:566815 CR14499    BioGRID  PubMed Two-hybrid 
    BioGRID:64660 BioGRID:63764 Cdc37    BioGRID  PubMed Two-hybrid 
    BioGRID:64660 BioGRID:58668 IP3K2    BioGRID  PubMed Two-hybrid 
    BioGRID:64660 BioGRID:77555 LpR1    BioGRID  PubMed Two-hybrid 
    BioGRID:64660 BioGRID:66771 Mst87F    BioGRID  PubMed Two-hybrid 
    BioGRID:64660 BioGRID:62977 Nnf1a    BioGRID  PubMed Two-hybrid 
    BioGRID:64660 BioGRID:68867 RpS15Aa    BioGRID  PubMed Two-hybrid 
    BioGRID:64660 BioGRID:67703 RpS3    BioGRID  PubMed Two-hybrid 
    BioGRID:64660 BioGRID:61486 SdhB    BioGRID  PubMed Two-hybrid 
    BioGRID:64660 BioGRID:60759 Ski6    BioGRID  PubMed Two-hybrid 
    BioGRID:64660 BioGRID:68766 Sucb    BioGRID  PubMed Two-hybrid 
    BioGRID:64660 BioGRID:60094 Tsp    BioGRID  PubMed Two-hybrid 
    BioGRID:64660 BioGRID:57878 dgt4    BioGRID  PubMed Two-hybrid 
    BioGRID:64660 BioGRID:62027 inv    BioGRID  PubMed Two-hybrid 
    BioGRID:64660 BioGRID:76780 lawc    BioGRID  PubMed Two-hybrid 
    BioGRID:64660 BioGRID:60845 nimC1    BioGRID  PubMed Two-hybrid 
    BioGRID:64660 BioGRID:58172 p115    BioGRID  PubMed Two-hybrid 
    BioGRID:64660 BioGRID:63919 sty    BioGRID  PubMed Two-hybrid 
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    General gene information

    Markers

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    cell morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    learning or memory IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    olfactory learning IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    rhabdomere development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    rhabdomere IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
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    General protein information

    Preferred Names
    CG11711 gene product from transcript CG11711-RC
    Names
    CG11711-PA
    CG11711-PB
    CG11711-PC
    CG11711-PD
    Mob2
    Mob2-PA
    Mob2-PB
    Mob2-PC
    Mob2-PD
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.3

      Range
      11515857..11555333, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140217.1 → NP_648474.1  Mob2, isoform C [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8IQG1
      Related
      FBpp0088369, FBtr0089330
      Conserved Domains (1) summary
      pfam03637
      Location:28 – 198
      Blast Score: 683
      Mob1_phocein; Mob1/phocein family

    2. NM_168460.1 → NP_729714.1  Mob2, isoform D [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8IQG1
      Related
      FBpp0088370, FBtr0089331
      Conserved Domains (1) summary
      pfam03637
      Location:163 – 333
      Blast Score: 687
      Mob1_phocein; Mob1/phocein family

    3. NM_168461.2 → NP_729715.2  Mob2, isoform A [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8IQG1
      Related
      FBpp0088371, FBtr0089332
      Conserved Domains (1) summary
      pfam03637
      Location:325 – 495
      Blast Score: 684
      Mob1_phocein; Mob1/phocein family

    4. NM_168462.1 → NP_729716.1  Mob2, isoform B [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      D6W4U9
      UniProtKB/Swiss-Prot
      Q8IQG1
      Related
      FBpp0088372, FBtr0089333
      Conserved Domains (1) summary
      pfam03637
      Location:134 – 304
      Blast Score: 686
      Mob1_phocein; Mob1/phocein family
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AE014296.4 AAN11873.1
    genomic AE014296.4 AAF50051.1
    genomic AE014296.4 AAN11874.2
    genomic AE014296.4 AAF50052.1
    mRNA BT124999.1 ADI46795.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IQG2.1 GenPept
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    Additional Links

    Gene LinkOut

      Supplemental Content