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USP27X ubiquitin specific peptidase 27, X-linked [ Homo sapiens (human) ]

Gene ID: 389856, updated on 8-May-2016
Official Symbol
USP27Xprovided by HGNC
Official Full Name
ubiquitin specific peptidase 27, X-linkedprovided by HGNC
Primary source
HGNC:HGNC:13486
See related
Ensembl:ENSG00000273820 Vega:OTTHUMG00000189037
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
USP27; USP22L
Orthologs
Location:
Xp11.23
Exon count:
1
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) X NC_000023.11 (49879867..49882565)
105 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (49644470..49647169)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene PAGE family member 4 Neighboring gene USP27X antisense RNA 1 (head to head) Neighboring gene cleavage and polyadenylation specific factor 1, 160kDa pseudogene Neighboring gene chloride voltage-gated channel 5 Neighboring gene microRNA 532

Related articles in PubMed

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
thiol-dependent ubiquitinyl hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
histone deubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
 
regulation of transcription, DNA-templated IBA
Inferred from Biological aspect of Ancestor
more info
 
ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
SAGA complex IBA
Inferred from Biological aspect of Ancestor
more info
 
Preferred Names
ubiquitin carboxyl-terminal hydrolase 27
Names
X-linked ubiquitin carboxyl-terminal hydrolase 27
deubiquitinating enzyme 27
ubiquitin specific protease 27, X chromosome
ubiquitin thioesterase 27
ubiquitin-specific-processing protease 27
NP_001138545.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001145073.2NP_001138545.1  ubiquitin carboxyl-terminal hydrolase 27

    See identical proteins and their annotated locations for NP_001138545.1

    Status: VALIDATED

    Source sequence(s)
    AC236430
    Consensus CDS
    CCDS65260.1
    UniProtKB/Swiss-Prot
    A6NNY8
    Related
    ENSP00000483631, OTTHUMP00000277508, ENST00000621775, OTTHUMT00000478481
    Conserved Domains (2) summary
    cd02660
    Location:78419
    Peptidase_C19D; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    pfam00443
    Location:77418
    UCH; Ubiquitin carboxyl-terminal hydrolase

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p2 Primary Assembly

    Range
    49879867..49882565
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018934.2 Alternate CHM1_1.1

    Range
    49724245..49726944
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)