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    Ect4 [ Drosophila melanogaster ]

    Gene ID: 38895, updated on 10-May-2012
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    Summary

    Official Symbol
    Ect4provided by Flybase
    Primary source
    FLYBASE:FBgn0262579
    Locus tag
    Dmel_CG43119
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0118547.272; CG13680; CG13681; CG34373; CG43119; CG7905; CG7915; Dmel\CG43119
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    Genomic context

    Location :
    66B5-66B6
    Sequence :
    Chromosome: 3L; NT_037436.3 (8056974..8101936)
    See Ect4 in Epigenomics, MapViewer

    Chromosome 3L - NT_037436.3Genomic Context describing neighboring genes Neighboring gene transfer RNA:CR32359 Neighboring gene transfer RNA:CR32360 Neighboring gene transfer RNA:CR32361 Neighboring gene transfer RNA:CR32362 Neighboring gene transfer RNA:CR32363 Neighboring gene CG42590 gene product from transcript CG42590-RA Neighboring gene CG42591 gene product from transcript CG42591-RA Neighboring gene CG7565 gene product from transcript CG7565-RA Neighboring gene mir-2501 stem loop Neighboring gene CG7927 gene product from transcript CG7927-RA Neighboring gene farinelli

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. A protein complex network of Drosophila melanogaster. Guruharsha KG, et al. Cell, 2011 Oct 28. PMID 22036573.
    2. Gene expression profiling implicates OXPHOS complexes in lifespan extension of flies over-expressing a small mitochondrial chaperone, Hsp22. Kim HJ, et al. Exp Gerontol, 2010 Aug. PMID 20036725.
    3. A genetic screen identifies new regulators of steroid-triggered programmed cell death in Drosophila. Wang L, et al. Genetics, 2008 Sep. PMID 18757938.
    4. Vector and parameters for targeted transgenic RNA interference in Drosophila melanogaster. Ni JQ, et al. Nat Methods, 2008 Jan. PMID 18084299.
    5. Sequence finishing and mapping of Drosophila melanogaster heterochromatin. Hoskins RA, et al. Science, 2007 Jun 15. PMID 17569867.

    See all (16) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:64320 BioGRID:67510 C15    BioGRID  PubMed Two-hybrid 
    BioGRID:64320 BioGRID:66352 CG8478    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:64320 BioGRID:61434 dream    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:64320 BioGRID:59888 mRpL24    BioGRID  PubMed Two-hybrid 
    BioGRID:64320 BioGRID:59774 sec5    BioGRID  PubMed Two-hybrid 
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    General gene information

    Markers

    Homology

    • Homologs of the Ect4 gene: The Ect4 gene is conserved in human, chimpanzee, , dog, mouse, rat, chicken, zebrafish, mosquito, and C.elegans.
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    General protein information

    Preferred Names
    CG43119 gene product from transcript CG43119-RI
    Names
    CG43119-PD
    CG43119-PE
    CG43119-PF
    CG43119-PG
    CG43119-PH
    CG43119-PI
    CG43119-PJ
    Ect4
    Ect4-PD
    Ect4-PE
    Ect4-PF
    Ect4-PG
    Ect4-PH
    Ect4-PI
    Ect4-PJ
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.3

      Range
      8056974..8101936
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001259733.1 → NP_001246662.1  Ect4, isoform I [Drosophila melanogaster]

      Status: REVIEWED

    2. NM_001104071.2 → NP_001097541.1  Ect4, isoform D [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8JNN1
      Related
      FBpp0111510
      Conserved Domains (6) summary
      cd09501
      Location:938 – 1006
      Blast Score: 344
      SAM_SARM1-like_repeat1; SAM domain ot SARM1-like proteins, repeat 1
      cd09502
      Location:1007 – 1072
      Blast Score: 305
      SAM_SARM1-like_repeat2; SAM domain of SARM1-like, repeat 2
      smart00454
      Location:938 – 1003
      Blast Score: 148
      SAM; Sterile alpha motif.
      pfam07647
      Location:1008 – 1072
      Blast Score: 119
      SAM_2; SAM domain (Sterile alpha motif)
      cl02500
      Location:698 – 812
      Blast Score: 90
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      cl15770
      Location:1092 – 1194
      Blast Score: 214
      TIR_2; TIR domain

    3. NM_001104074.2 → NP_001097544.1  Ect4, isoform G [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8JNN2
      Related
      FBpp0111513
      Conserved Domains (6) summary
      cd09501
      Location:863 – 931
      Blast Score: 346
      SAM_SARM1-like_repeat1; SAM domain ot SARM1-like proteins, repeat 1
      cd09502
      Location:932 – 997
      Blast Score: 305
      SAM_SARM1-like_repeat2; SAM domain of SARM1-like, repeat 2
      smart00454
      Location:863 – 928
      Blast Score: 148
      SAM; Sterile alpha motif.
      pfam07647
      Location:933 – 997
      Blast Score: 119
      SAM_2; SAM domain (Sterile alpha motif)
      cl02500
      Location:623 – 737
      Blast Score: 89
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      cl15770
      Location:1017 – 1119
      Blast Score: 213
      TIR_2; TIR domain

    4. NM_001104075.2 → NP_001097545.1  Ect4, isoform H [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8JNN3
      Related
      FBpp0111514
      Conserved Domains (6) summary
      cd09501
      Location:687 – 755
      Blast Score: 343
      SAM_SARM1-like_repeat1; SAM domain ot SARM1-like proteins, repeat 1
      cd09502
      Location:756 – 821
      Blast Score: 306
      SAM_SARM1-like_repeat2; SAM domain of SARM1-like, repeat 2
      smart00454
      Location:687 – 752
      Blast Score: 148
      SAM; Sterile alpha motif.
      pfam07647
      Location:757 – 821
      Blast Score: 119
      SAM_2; SAM domain (Sterile alpha motif)
      cl02500
      Location:447 – 561
      Blast Score: 89
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      cl15770
      Location:841 – 943
      Blast Score: 211
      TIR_2; TIR domain

    5. NM_001043129.2 → NP_001036594.1  Ect4, isoform F [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q6IDD9
      Related
      FBpp0111512
      Conserved Domains (6) summary
      cd09501
      Location:687 – 755
      Blast Score: 344
      SAM_SARM1-like_repeat1; SAM domain ot SARM1-like proteins, repeat 1
      cd09502
      Location:756 – 821
      Blast Score: 306
      SAM_SARM1-like_repeat2; SAM domain of SARM1-like, repeat 2
      smart00454
      Location:687 – 752
      Blast Score: 148
      SAM; Sterile alpha motif.
      pfam07647
      Location:757 – 821
      Blast Score: 119
      SAM_2; SAM domain (Sterile alpha motif)
      cl02500
      Location:447 – 561
      Blast Score: 89
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      cl15770
      Location:841 – 943
      Blast Score: 212
      TIR_2; TIR domain

    6. NM_001259734.1 → NP_001246663.1  Ect4, isoform J [Drosophila melanogaster]

      Status: REVIEWED

    7. NM_168254.2 → NP_729327.1  Ect4, isoform E [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q6IDD9
      Related
      FBpp0111511
      Conserved Domains (6) summary
      cd09501
      Location:661 – 729
      Blast Score: 346
      SAM_SARM1-like_repeat1; SAM domain ot SARM1-like proteins, repeat 1
      cd09502
      Location:730 – 795
      Blast Score: 308
      SAM_SARM1-like_repeat2; SAM domain of SARM1-like, repeat 2
      smart00454
      Location:661 – 726
      Blast Score: 149
      SAM; Sterile alpha motif.
      pfam07647
      Location:731 – 795
      Blast Score: 120
      SAM_2; SAM domain (Sterile alpha motif)
      cl02500
      Location:421 – 535
      Blast Score: 87
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      cl15770
      Location:815 – 917
      Blast Score: 208
      TIR_2; TIR domain
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AE014296.4 AFH04333.1
    genomic AE014296.4 ABW08490.1
    genomic AE014296.4 ABW08491.1
    genomic AE014296.4 ABW08492.1
    genomic AE014296.4 ABI31243.1
    mRNA BT014666.1 AAT27290.1
    genomic AE014296.4 AFH04334.1
    mRNA AY075346.1 AAL68207.1
    genomic AE014296.4 AAN12011.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6IDD9.1 GenPept
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    Additional Links

    Gene LinkOut

      Supplemental Content