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    akirin [ Drosophila melanogaster ]

    Gene ID: 38821, updated on 9-May-2012
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    Summary

    Official Symbol
    akirinprovided by Flybase
    Primary source
    FLYBASE:FBgn0082598
    Locus tag
    Dmel_CG8580
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Akirin; anon-WO0118547.397; bhr; CG8580; DmAkirin; Dmel\CG8580; EP(3)0906
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    Genomic context

    Location :
    65F7-65F7
    Sequence :
    Chromosome: 3L; NT_037436.3 (7362900..7366958)
    See akirin in Epigenomics, MapViewer

    Chromosome 3L - NT_037436.3Genomic Context describing neighboring genes Neighboring gene CG8583 gene product from transcript CG8583-RA Neighboring gene CG8582 gene product from transcript CG8582-RD Neighboring gene CG32380 gene product from transcript CG32380-RA Neighboring gene smallminded

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Genome-wide RNAi screen identifies genes involved in intestinal pathogenic bacterial infection. Cronin SJ, et al. Science, 2009 Jul 17. PMID 19520911.
    2. Two roles for the Drosophila IKK complex in the activation of Relish and the induction of antimicrobial peptide genes. Ertürk-Hasdemir D, et al. Proc Natl Acad Sci U S A, 2009 Jun 16. PMID 19497884.
    3. Akirins are highly conserved nuclear proteins required for NF-kappaB-dependent gene expression in drosophila and mice. Goto A, et al. Nat Immunol, 2008 Jan. PMID 18066067.
    4. The Drosophila insulator proteins CTCF and CP190 link enhancer blocking to body patterning. Mohan M, et al. EMBO J, 2007 Oct 3. PMID 17805343.
    5. Sequence finishing and mapping of Drosophila melanogaster heterochromatin. Hoskins RA, et al. Science, 2007 Jun 15. PMID 17569867.

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:64261 BioGRID:58653 Bap60    BioGRID  PubMed Two-hybrid 
    BioGRID:64261 BioGRID:57628 CG11380    BioGRID  PubMed Two-hybrid 
    BioGRID:64261 BioGRID:66688 CG11656    BioGRID  PubMed Two-hybrid 
    BioGRID:64261 BioGRID:63790 CG11815    BioGRID  PubMed Two-hybrid 
    BioGRID:64261 BioGRID:58678 CG12725    BioGRID  PubMed Two-hybrid 
    BioGRID:64261 BioGRID:66384 CG12811    BioGRID  PubMed Two-hybrid 
    BioGRID:64261 BioGRID:61207 CG13084    BioGRID  PubMed Two-hybrid 
    BioGRID:64261 BioGRID:67847 CG13617    BioGRID  PubMed Two-hybrid 
    BioGRID:64261 BioGRID:68045 CG14540    BioGRID  PubMed Two-hybrid 
    BioGRID:64261 BioGRID:66582 CG14739    BioGRID  PubMed Two-hybrid 
    BioGRID:64261 BioGRID:60369 CG17855    BioGRID  PubMed Two-hybrid 
    BioGRID:64261 BioGRID:64527 CG18178    BioGRID  PubMed Two-hybrid 
    BioGRID:64261 BioGRID:58464 CG18292    BioGRID  PubMed Two-hybrid 
    BioGRID:64261 BioGRID:58147 CG1999    BioGRID  PubMed Two-hybrid 
    BioGRID:64261 BioGRID:73196 CG30497    BioGRID  PubMed Two-hybrid 
    BioGRID:64261 BioGRID:60365 CG3769    BioGRID  PubMed Two-hybrid 
    BioGRID:64261 BioGRID:61068 CG5674    BioGRID  PubMed Two-hybrid 
    BioGRID:64261 BioGRID:66178 CG7352    BioGRID  PubMed Two-hybrid 
    BioGRID:64261 BioGRID:62020 CG9027    BioGRID  PubMed Two-hybrid 
    BioGRID:64261 BioGRID:64793 Klc    BioGRID  PubMed Two-hybrid 
    BioGRID:64261 BioGRID:68683 Ppn    BioGRID  PubMed Two-hybrid 
    BioGRID:64261 BioGRID:66749 Rbp4    BioGRID  PubMed Two-hybrid 
    BioGRID:64261 BioGRID:63374 TBPH    BioGRID  PubMed Two-hybrid 
    BioGRID:64261 BioGRID:62418 chn    BioGRID  PubMed Two-hybrid 
    BioGRID:64261 BioGRID:60622 mre11    BioGRID  PubMed Two-hybrid 
    BioGRID:64261 BioGRID:69326 pnr    BioGRID  PubMed Phenotypic Enhancement 
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    General gene information

    Markers

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    		  
    Process Evidence Code Pubs
    defense response to Gram-negative bacterium IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    embryo development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    muscle attachment IMP
    Inferred from Mutant Phenotype
    more info
    		  
    muscle organ development IMP
    Inferred from Mutant Phenotype
    more info
    		  
    positive regulation of innate immune response IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    nucleus IDA
    Inferred from Direct Assay
    more info
    		  
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    General protein information

    Preferred Names
    CG8580 gene product from transcript CG8580-RD
    Names
    CG8580-PA
    CG8580-PB
    CG8580-PC
    CG8580-PD
    CG8580-PE
    akirin
    akirin-PA
    akirin-PB
    akirin-PC
    akirin-PD
    akirin-PE
    bhringi
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.3

      Range
      7362900..7366958
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001202130.1 → NP_001189059.1  akirin, isoform D [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VS59

    2. NM_168211.2 → NP_729249.1  akirin, isoform B [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VS59
      Related
      FBpp0076560

    3. NM_001202131.1 → NP_001189060.1  akirin, isoform E [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VS59

    4. NM_139856.3 → NP_648113.1  akirin, isoform A [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VS59
      Related
      FBpp0076559

    5. NM_001202129.1 → NP_001189058.1  akirin, isoform C [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VS59
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AE014296.4 AAF50569.1
    mRNA AY095189.1 AAM12282.1
    genomic AE014296.4 AAN12062.1
    genomic AE014296.4 ADV37495.1
    genomic AE014296.4 ADV37496.1
    genomic AE014296.4 ADV37497.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VS59.1 GenPept
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    Additional Links

    Gene LinkOut

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