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Hcrtr2 hypocretin (orexin) receptor 2 [ Mus musculus (house mouse) ]

Gene ID: 387285, updated on 28-May-2016
Official Symbol
Hcrtr2provided by MGI
Official Full Name
hypocretin (orexin) receptor 2provided by MGI
Primary source
MGI:MGI:2680765
See related
Ensembl:ENSMUSG00000032360 Vega:OTTMUSG00000044825
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
OX2R; mOXR2; mOX2aR; mOX2bR
Orthologs
Location:
9; 9 D
Exon count:
7
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 9 NC_000075.6 (76225880..76323868, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (76073687..76171385, complement)

Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase-like 1 Neighboring gene GDNF family receptor alpha like Neighboring gene family with sequence similarity 83, member B Neighboring gene predicted gene, 34158

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
G-protein coupled receptor activity ISO
Inferred from Sequence Orthology
more info
 
neuropeptide receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
orexin receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
orexin receptor activity ISO
Inferred from Sequence Orthology
more info
 
peptide binding IBA
Inferred from Biological aspect of Ancestor
more info
 
peptide hormone binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
signal transducer activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
G-protein coupled receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
cellular response to hormone stimulus IBA
Inferred from Biological aspect of Ancestor
more info
 
circadian sleep/wake cycle process IEA
Inferred from Electronic Annotation
more info
 
feeding behavior IBA
Inferred from Biological aspect of Ancestor
more info
 
feeding behavior ISO
Inferred from Sequence Orthology
more info
 
neuropeptide signaling pathway ISO
Inferred from Sequence Orthology
more info
 
phospholipase C-activating G-protein coupled receptor signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
regulation of circadian sleep/wake cycle, sleep IBA
Inferred from Biological aspect of Ancestor
more info
 
response to peptide IBA
Inferred from Biological aspect of Ancestor
more info
 
signal transduction IEA
Inferred from Electronic Annotation
more info
 
synaptic transmission IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
orexin receptor type 2
Names
hypocretin receptor type 2
ox-2-R
ox2-R

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_198962.3NP_945200.1  orexin receptor type 2

    See identical proteins and their annotated locations for NP_945200.1

    Status: PROVISIONAL

    Source sequence(s)
    AC140311
    Consensus CDS
    CCDS23350.1
    UniProtKB/Swiss-Prot
    P58308
    Related
    ENSMUSP00000058230, OTTMUSP00000065830, ENSMUST00000063140, OTTMUST00000117816
    Conserved Domains (3) summary
    pfam03827
    Location:383443
    Orexin_rec2; Orexin receptor type 2
    pfam00001
    Location:77364
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:65185
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000075.6 Reference GRCm38.p3 C57BL/6J

    Range
    76225880..76323868 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011242766.1XP_011241068.1  

    See identical proteins and their annotated locations for XP_011241068.1

    UniProtKB/Swiss-Prot
    P58308
    Related
    ENSMUSP00000139377, OTTMUSP00000065831, ENSMUST00000184757, OTTMUST00000117817
    Conserved Domains (3) summary
    pfam03827
    Location:383443
    Orexin_rec2; Orexin receptor type 2
    pfam00001
    Location:77364
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:65185
    7tm_4; Olfactory receptor

Alternate Mm_Celera

Genomic

  1. AC_000031.1 Alternate Mm_Celera

    Range
    73390040..73487756 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)