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CG11353 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38560, updated on 4-Apr-2024

Summary

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Official Symbol
CG11353provided by FlyBase
Primary source
FLYBASE:FBgn0035557
Locus tag
Dmel_CG11353
See related
AllianceGenome:FB:FBgn0035557
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-WO0172774.162; Dmel\CG11353
Summary
Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Is expressed in presumptive embryonic/larval system. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
64B9-64B9; 3-12 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (4533170..4539270)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (4533170..4539270)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Neurotrophin 1 Neighboring gene Tie-like receptor tyrosine kinase Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cloning of the neurodegeneration gene drop-dead and characterization of additional phenotypes of its mutation. Blumenthal EM. Fly (Austin), 2008 Jul-Aug. PMID 18719404, Free PMC Article
  2. Selection for long and short sleep duration in Drosophila melanogaster reveals the complex genetic network underlying natural variation in sleep. Harbison ST, et al. PLoS Genet, 2017 Dec. PMID 29240764, Free PMC Article
  3. Cold acclimation wholly reorganizes the Drosophila melanogaster transcriptome and metabolome. MacMillan HA, et al. Sci Rep, 2016 Jun 30. PMID 27357258, Free PMC Article
  4. Transcriptomic analysis of inbreeding depression in cold-sensitive Drosophila melanogaster shows upregulation of the immune response. Vermeulen CJ, et al. J Evol Biol, 2013 Sep. PMID 23944235
  5. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Neely GG, et al. Cell, 2010 Nov 12. PMID 21074052, Free PMC Article

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables acyltransferase activity, transferring groups other than amino-acyl groups IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG11353-PA
CG11353-PB
NP_647915.1
NP_729013.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    4533170..4539270
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_139658.4 → NP_647915.1  uncharacterized protein Dmel_CG11353, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_647915.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VZA7
    Related
    FBpp0073165
    Conserved Domains (3) summary
    smart00703
    Location:118 → 243
    NRF; N-terminal domain in C. elegans NRF-6 (Nose Resistant to Fluoxetine-4) and NDG-4 (resistant to nordihydroguaiaretic acid-4)
    COG1835
    Location:349 → 752
    OafA; Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains [Cell wall/membrane/envelope biogenesis]
    pfam01757
    Location:352 → 729
    Acyl_transf_3; Acyltransferase family

  2. NM_168093.3 → NP_729013.1  uncharacterized protein Dmel_CG11353, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_729013.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VZA7
    Related
    FBpp0073164
    Conserved Domains (3) summary
    smart00703
    Location:118 → 243
    NRF; N-terminal domain in C. elegans NRF-6 (Nose Resistant to Fluoxetine-4) and NDG-4 (resistant to nordihydroguaiaretic acid-4)
    COG1835
    Location:349 → 752
    OafA; Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains [Cell wall/membrane/envelope biogenesis]
    pfam01757
    Location:352 → 729
    Acyl_transf_3; Acyltransferase family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VZA7 Q9VZA7

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