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CG12078 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38401, updated on 4-Apr-2024

Summary

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Official Symbol
CG12078provided by FlyBase
Primary source
FLYBASE:FBgn0035426
Locus tag
Dmel_CG12078
See related
AllianceGenome:FB:FBgn0035426
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
24656659; Dmel\CG12078
Summary
Predicted to enable protein serine/threonine phosphatase activity. Predicted to be involved in protein dephosphorylation. Predicted to be located in cytoplasm. Orthologous to human CTDNEP1 (CTD nuclear envelope phosphatase 1). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
63C1-63C1; 3-7 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (3243274..3244294, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (3243274..3244294, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene La-related protein 4B Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45424 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Negative modulation of bone morphogenetic protein signaling by Dullard during wing vein formation in Drosophila. Liu Z, et al. Dev Growth Differ, 2011 Aug. PMID 21790556
  2. Viability, longevity, and egg production of Drosophila melanogaster are regulated by the miR-282 microRNA. Vilmos P, et al. Genetics, 2013 Oct. PMID 23852386, Free PMC Article
  3. A large-scale resource for tissue-specific CRISPR mutagenesis in Drosophila. Port F, et al. Elife, 2020 Feb 13. PMID 32053108, Free PMC Article
  4. Identification of neural outgrowth genes using genome-wide RNAi. Sepp KJ, et al. PLoS Genet, 2008 Jul 4. PMID 18604272, Free PMC Article
  5. Genetic variation in food choice behaviour of amino acid-deprived Drosophila. Toshima N, et al. J Insect Physiol, 2014 Oct. PMID 25010547

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein serine/threonine phosphatase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in protein dephosphorylation ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG12078-PA
CG12078-PB
NP_001246593.1
NP_647795.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    3243274..3244294 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001259664.1 → NP_001246593.1  uncharacterized protein Dmel_CG12078, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001246593.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9NDG3
    Conserved Domains (1) summary
    TIGR02251
    Location:53 → 220
    HIF-SF_euk; Dullard-like phosphatase domain

  2. NM_139538.3 → NP_647795.2  uncharacterized protein Dmel_CG12078, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_647795.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q4V5L7, Q9VZS0
    Conserved Domains (1) summary
    TIGR02251
    Location:70 → 237
    HIF-SF_euk; Dullard-like phosphatase domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
M9NDG3 M9NDG3
Q9VZS0 Q9VZS0

Gene LinkOut

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