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Parl presenilin associated, rhomboid-like [ Mus musculus (house mouse) ]

Gene ID: 381038, updated on 18-Oct-2014
Official Symbol
Parlprovided by MGI
Official Full Name
presenilin associated, rhomboid-likeprovided by MGI
Primary source
MGI:MGI:1277152
See related
Ensembl:ENSMUSG00000033918; Vega:OTTMUSG00000025306
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Psarl; PSARL1; PRO2207; PSENIP2; D16Ertd607e
See Parl in Epigenomics, MapViewer
Location:
16 A3; 16 12.4 cM
Exon count:
10
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 16 NC_000082.6 (20279820..20302394, complement)

Chromosome 16 - NC_000082.6Genomic Context describing neighboring genes Neighboring gene YEATS domain containing 2 Neighboring gene SMT3 suppressor of mif two 3 homolog 2 pseudogene Neighboring gene MAP6 domain containing 1 Neighboring gene cytochrome P450, family 2, subfamily ab, polypeptide 1 Neighboring gene ATP-binding cassette, sub-family C (CFTR/MRP), member 5

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
endopeptidase activity ISO
Inferred from Sequence Orthology
more info
 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
peptidase activity IEA
Inferred from Electronic Annotation
more info
 
serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
serine-type peptidase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
negative regulation of intrinsic apoptotic signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of release of cytochrome c from mitochondria IMP
Inferred from Mutant Phenotype
more info
PubMed 
proteolysis ISO
Inferred from Sequence Orthology
more info
 
regulation of reactive oxygen species metabolic process ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrial inner membrane IMP
Inferred from Mutant Phenotype
more info
PubMed 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion ISO
Inferred from Sequence Orthology
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
presenilins-associated rhomboid-like protein, mitochondrial
Names
presenilins-associated rhomboid-like protein, mitochondrial
mitochondrial intramembrane-cleaving protease PARL
NP_001005767.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005767.4NP_001005767.1  presenilins-associated rhomboid-like protein, mitochondrial precursor

    See proteins identical to NP_001005767.1

    Status: PROVISIONAL

    Source sequence(s)
    AC154526
    Consensus CDS
    CCDS28044.1
    UniProtKB/Swiss-Prot
    Q5XJY4
    Related
    ENSMUSP00000045361, OTTMUSP00000030672, ENSMUST00000048642, OTTMUST00000062273
    Conserved Domains (1) summary
    pfam01694
    Location:207348
    Rhomboid; Rhomboid family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000082.6 

    Range
    20279820..20302394
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006522312.1XP_006522375.1  

    Conserved Domains (1) summary
    pfam01694
    Location:86227
    Rhomboid; Rhomboid family

RNA

  1. XR_384575.1 RNA Sequence

Alternate Mm_Celera

Genomic

  1. AC_000038.1 

    Range
    20843305..20865847
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)