CG13900 [Drosophila melanogaster] - Gene

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Summary

Official Symbol: CG13900provided by Flybase
Primary source: FLYBASE:FBgn0035162
Locus tag: Dmel_CG13900
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: Dmel\CG13900; SF3B3

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Genomic context

Location :: 61D2-61D2

Sequence :: Chromosome: 3L; NT_037436.3 (826710..833402, complement)

See CG13900 in Epigenomics, MapViewer

Chromosome 3L - NT_037436.3 Genomic Context describing neighboring genes

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Genomic regions, transcripts, and products

Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Go to reference sequence details

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Bibliography

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Submit: New GeneRIF Correction

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Interactions

Products	Interactant	Other Gene	Source	Pubs	Description
BioGRID:63648	BioGRID:67008	Akt1	BioGRID	PubMed	Two-hybrid
BioGRID:63648	BioGRID:57560	CG13373	BioGRID	PubMed	Two-hybrid
BioGRID:63648	BioGRID:61707	CG14744	BioGRID	PubMed	Two-hybrid
BioGRID:63648	BioGRID:63359	CG15800	BioGRID	PubMed	Two-hybrid
BioGRID:63648	BioGRID:64740	CG5642	BioGRID	PubMed	Two-hybrid
BioGRID:63648	BioGRID:67527	CG6800	BioGRID	PubMed	Two-hybrid
BioGRID:63648	BioGRID:58854	CG8128	BioGRID	PubMed	Two-hybrid
BioGRID:63648	BioGRID:60245	CG8455	BioGRID	PubMed	Two-hybrid
BioGRID:63648	BioGRID:62567	Cdk4	BioGRID	PubMed	Two-hybrid
BioGRID:63648	BioGRID:62461	Cdk5	BioGRID	PubMed	Two-hybrid
BioGRID:63648	BioGRID:58898	CycD	BioGRID	PubMed	Two-hybrid
BioGRID:63648	BioGRID:68567	CycG	BioGRID	PubMed	Two-hybrid
BioGRID:63648	BioGRID:65669	CycH	BioGRID	PubMed	Two-hybrid
BioGRID:63648	BioGRID:63921	CycJ	BioGRID	PubMed	Two-hybrid
BioGRID:63648	BioGRID:72482	CycK	BioGRID	PubMed	Two-hybrid
BioGRID:63648	BioGRID:61336	E2f2	BioGRID	PubMed	Two-hybrid
BioGRID:63648	BioGRID:71509	Hsp60B	BioGRID	PubMed	Two-hybrid
BioGRID:63648	BioGRID:59745	Mad	BioGRID	PubMed	Two-hybrid
BioGRID:63648	BioGRID:65629	SAK	BioGRID	PubMed	Two-hybrid
BioGRID:63648	BioGRID:67396	Sirt2	BioGRID	PubMed	Two-hybrid
BioGRID:63648	BioGRID:60206	cdc14	BioGRID	PubMed	Two-hybrid
BioGRID:63648	BioGRID:61832	dap	BioGRID	PubMed	Two-hybrid
BioGRID:63648	BioGRID:61361	nompB	BioGRID	PubMed	Two-hybrid
BioGRID:63648	BioGRID:69325	plu	BioGRID	PubMed	Two-hybrid
BioGRID:63648	BioGRID:61701	ptc	BioGRID	PubMed	Two-hybrid
BioGRID:63648	BioGRID:65883	rev7	BioGRID	PubMed	Two-hybrid
BioGRID:63648	BioGRID:58031	rux	BioGRID	PubMed	Two-hybrid

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General gene information

Homology

Homologs of the CG13900 gene: The CG13900 gene is conserved in human, chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, mosquito, C.elegans, S.pombe, M.grisea, N.crassa, A.thaliana, and rice.

Pathways from BioSystems

Gene Expression, organism-specific biosystem (from REACTOME)
Gene Expression, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Processing of Capped Intron-Containing Pre-mRNA, organism-specific biosystem (from REACTOME)
Processing of Capped Intron-Containing Pre-mRNA, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Spliceosome, organism-specific biosystem (from KEGG)
Spliceosome, organism-specific biosystemAfter transcription, eukaryotic mRNA precursors contain protein-coding exons and noncoding introns. In the following splicing, introns are excised and exons are joined by a macromolecular complex, th...
Spliceosome, conserved biosystem (from KEGG)
Spliceosome, conserved biosystemAfter transcription, eukaryotic mRNA precursors contain protein-coding exons and noncoding introns. In the following splicing, introns are excised and exons are joined by a macromolecular complex, th...
Spliceosome, U2-snRNP, organism-specific biosystem (from KEGG)
Spliceosome, U2-snRNP, organism-specific biosystemStructural complex; Genetic information processing; Spliceosome
mRNA Splicing, organism-specific biosystem (from REACTOME)
mRNA Splicing, organism-specific biosystemcomputationally inferred pathway (not manually curated)
mRNA Splicing - Major Pathway, organism-specific biosystem (from REACTOME)
mRNA Splicing - Major Pathway, organism-specific biosystemcomputationally inferred pathway (not manually curated)
mRNA Splicing - Minor Pathway, organism-specific biosystem (from REACTOME)
mRNA Splicing - Minor Pathway, organism-specific biosystemcomputationally inferred pathway (not manually curated)
mRNA processing, organism-specific biosystem (from WikiPathways)
mRNA processing, organism-specific biosystemThis process describes the conversion of precursor messenger RNA into mature messenger RNA (mRNA). The pre-mRNA molecule undergoes three main modifications. These modifications are 5' capping, 3' pol...

Gene Ontology Provided by FlyBase

Function	Evidence Code	Pubs
damaged DNA binding	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
mitotic spindle organization	IMP Inferred from Mutant Phenotype more info	PubMed
neurogenesis	IMP Inferred from Mutant Phenotype more info
nuclear mRNA splicing, via spliceosome	IC Inferred by Curator more info	PubMed
nuclear mRNA splicing, via spliceosome	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Component	Evidence Code	Pubs
U2 snRNP	ISS Inferred from Sequence or Structural Similarity more info	PubMed
catalytic step 2 spliceosome	IDA Inferred from Direct Assay more info	PubMed
precatalytic spliceosome	IDA Inferred from Direct Assay more info	PubMed
small nuclear ribonucleoprotein complex	ISS Inferred from Sequence or Structural Similarity more info	PubMed

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General protein information

Preferred Names: CG13900 gene product from transcript CG13900-RA

Names: CG13900; CG13900-PA; CG13900-PB; putative damaged DNA-binding activity; splicing factor 3b subunit 3

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NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NT_037436.3

Range

826710..833402, complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_167842.1 → NP_728546.1 CG13900, isoform A [Drosophila melanogaster]

Status: REVIEWED

UniProtKB/TrEMBL

Q9W0M7

Related

FBpp0072494, FBtr0072597

Conserved Domains (2) summary

pfam03178
Location:872 – 1194
Blast Score: 908

CPSF_A; CPSF A subunit region

pfam10433
Location:76 – 576
Blast Score: 632

MMS1_N; Mono-functional DNA-alkylating methyl methanesulfonate N-term
NM_138215.2 → NP_612059.1 CG13900, isoform B [Drosophila melanogaster]

Status: REVIEWED

UniProtKB/TrEMBL

Q8T9L6

Related

FBpp0072495, FBtr0072598

Conserved Domains (1) summary

pfam03178
Location:333 – 655
Blast Score: 915

CPSF_A; CPSF A subunit region

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Related Sequences

Nucleotide		Protein
Heading	Accession and Version	Protein
genomic	AE014296.4	AAF47416.2
mRNA	BT021424.1	AAX33572.1
mRNA	BT120391.1	ADD20765.1
genomic	AE014296.4	AAN11452.1
mRNA	AY069239.1	AAL39384.1