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Atac3 Ada2a-containing complex component 3 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38055, updated on 4-Apr-2024

Summary

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Official Symbol
Atac3provided by FlyBase
Official Full Name
Ada2a-containing complex component 3provided by FlyBase
Primary source
FLYBASE:FBgn0052343
Locus tag
Dmel_CG32343
See related
AllianceGenome:FB:FBgn0052343
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG32343; cg6994; CG6994; dAtac3; dATAC3; Dmel\CG32343
Summary
Predicted to enable transcription cis-regulatory region binding activity. Involved in chromatin remodeling and histone acetylation. Part of ATAC complex. Is expressed in organism. Orthologous to several human genes including GABPB2 (GA binding protein transcription factor subunit beta 2). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See Atac3 in Genome Data Viewer
Location:
61C1-61C1; 3-0.5 cM
Exon count:
10
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (324985..327992, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (324985..327992, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene four wheel drive Neighboring gene deadbeat Neighboring gene uncharacterized protein Neighboring gene Protein tyrosine phosphatase Meg Neighboring gene methuselah-like 9 Neighboring gene methuselah-like 10

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. ATAC is a double histone acetyltransferase complex that stimulates nucleosome sliding. Suganuma T, et al. Nat Struct Mol Biol, 2008 Apr. PMID 18327268
  2. Lint-O cooperates with L(3)mbt in target gene suppression to maintain homeostasis in fly ovary and brain. Yamamoto-Matsuda H, et al. EMBO Rep, 2022 Oct 6. PMID 35993198, Free PMC Article
  3. A metazoan ATAC acetyltransferase subunit that regulates mitogen-activated protein kinase signaling is related to an ancient molybdopterin synthase component. Suganuma T, et al. Mol Cell Proteomics, 2012 May. PMID 22345504, Free PMC Article
  4. The ATAC acetyltransferase complex coordinates MAP kinases to regulate JNK target genes. Suganuma T, et al. Cell, 2010 Sep 3. PMID 20813260
  5. In vivo functional characterization of the SARS-Coronavirus 3a protein in Drosophila. Wong SL, et al. Biochem Biophys Res Commun, 2005 Nov 18. PMID 16212942, Free PMC Article

See all (42) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables transcription cis-regulatory region binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in chromatin remodeling IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of ATAC complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of ATAC complex IPI
Inferred from Physical Interaction
more info
 PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Ada2a-containing complex component 3
Names
ATAC complex component 3
Atac3-PB
Atac3-PC
Atac3-PD
Atac3-PE
CG32343-PB
CG32343-PC
CG32343-PD
CG32343-PE

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    324985..327992 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001259602.2 → NP_001246531.1  Ada2a-containing complex component 3, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001246531.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9NFF9
    Conserved Domains (4) summary
    cd00204
    Location:81 → 204
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:90 → 181
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:58 → 106
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:88 → 116
    ANK; ANK repeat [structural motif]

  2. NM_167828.4 → NP_728520.2  Ada2a-containing complex component 3, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_728520.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W0R7
    Conserved Domains (4) summary
    cd00204
    Location:81 → 204
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:90 → 181
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:58 → 106
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:88 → 116
    ANK; ANK repeat [structural motif]

  3. NM_001144394.2 → NP_001137866.1  Ada2a-containing complex component 3, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001137866.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W0R7
    Conserved Domains (4) summary
    cd00204
    Location:81 → 204
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:90 → 181
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:58 → 106
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:88 → 116
    ANK; ANK repeat [structural motif]

  4. NM_001274275.1 → NP_001261204.1  Ada2a-containing complex component 3, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001261204.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9NFF9
    Conserved Domains (4) summary
    cd00204
    Location:81 → 204
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:90 → 181
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:58 → 106
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:88 → 116
    ANK; ANK repeat [structural motif]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
M9NFF9 M9NFF9
Q9W0R7 Q9W0R7

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