RpL19 Ribosomal protein L19 [Drosophila melanogaster] - Gene

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Summary

Official Symbol: RpL19provided by Flybase
Official Full Name: Ribosomal protein L19provided by Flybase
Primary source: FLYBASE:FBgn0002607
Locus tag: Dmel_CG2746
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: anon-EST:Posey33; CG2746; Dmel\CG2746; E(Dl)KP135; l(2)k03704; L19; M(2)60E; M(2)a; M(2)c; M60E; rpl19; rpL19

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Genomic context

Location :: 60E11-60E11; 2-108 cM

Sequence :: Chromosome: 2R; NT_033778.3 (20855968..20857070, complement)

See RpL19 in Epigenomics, MapViewer

Chromosome 2R - NT_033778.3 Genomic Context describing neighboring genes

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Genomic regions, transcripts, and products

Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Go to reference sequence details

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Bibliography

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Submit: New GeneRIF Correction

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Interactions

Products	Interactant	Other Gene	Source	Pubs	Description
BioGRID:63563	BioGRID:65135	Aats-tyr	BioGRID	PubMed	Two-hybrid
BioGRID:63563	BioGRID:63998	CG11586	BioGRID	PubMed	Two-hybrid
BioGRID:63563	BioGRID:65069	CG13074	BioGRID	PubMed	Two-hybrid
BioGRID:63563	BioGRID:61283	CG15475	BioGRID	PubMed	Two-hybrid
BioGRID:63563	BioGRID:66547	CG17360	BioGRID	PubMed	Two-hybrid
BioGRID:63563	BioGRID:58683	CG32635	BioGRID	PubMed	Two-hybrid
BioGRID:63563	BioGRID:62794	CG5174	BioGRID	PubMed	Two-hybrid
BioGRID:63563	BioGRID:67172	CG7379	BioGRID	PubMed	Two-hybrid
BioGRID:63563	BioGRID:57823	N	BioGRID	PubMed	Phenotypic Enhancement
BioGRID:63563	BioGRID:66171	Poxm	BioGRID	PubMed	Two-hybrid
BioGRID:63563	BioGRID:57920	ctp	BioGRID	PubMed	Two-hybrid
BioGRID:63563	BioGRID:60497	da	BioGRID	PubMed	Two-hybrid
BioGRID:63563	BioGRID:58994	if	BioGRID	PubMed	Phenotypic Enhancement
BioGRID:63563	BioGRID:65676	mub	BioGRID	PubMed	Two-hybrid
BioGRID:63563	BioGRID:59774	sec5	BioGRID	PubMed	Two-hybrid

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General gene information

Homology

Homologs of the RpL19 gene: The RpL19 gene is conserved in human, chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, mosquito, C.elegans, S.pombe, S.cerevisiae, K.lactis, E.gossypii, M.grisea, N.crassa, A.thaliana, rice, and P.falciparum.

Pathways from BioSystems

Cap-dependent Translation Initiation, organism-specific biosystem (from REACTOME)
Cap-dependent Translation Initiation, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Eukaryotic Translation Elongation, organism-specific biosystem (from REACTOME)
Eukaryotic Translation Elongation, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Eukaryotic Translation Initiation, organism-specific biosystem (from REACTOME)
Eukaryotic Translation Initiation, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Eukaryotic Translation Termination, organism-specific biosystem (from REACTOME)
Eukaryotic Translation Termination, organism-specific biosystemcomputationally inferred pathway (not manually curated)
GTP hydrolysis and joining of the 60S ribosomal subunit, organism-specific biosystem (from REACTOME)
GTP hydrolysis and joining of the 60S ribosomal subunit, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Gene Expression, organism-specific biosystem (from REACTOME)
Gene Expression, organism-specific biosystemcomputationally inferred pathway (not manually curated)
L13a-mediated translational silencing of Ceruloplasmin expression, organism-specific biosystem (from REACTOME)
L13a-mediated translational silencing of Ceruloplasmin expression, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Metabolism of proteins, organism-specific biosystem (from REACTOME)
Metabolism of proteins, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Peptide chain elongation, organism-specific biosystem (from REACTOME)
Peptide chain elongation, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Ribosome, organism-specific biosystem (from KEGG)
Ribosome, organism-specific biosystem
Ribosome
Ribosome, conserved biosystem (from KEGG)
Ribosome, conserved biosystem
Ribosome
Ribosome, eukaryotes, organism-specific biosystem (from KEGG)
Ribosome, eukaryotes, organism-specific biosystemStructural complex; Genetic information processing; Ribosome
SRP-dependent cotranslational protein targeting to membrane, organism-specific biosystem (from REACTOME)
SRP-dependent cotranslational protein targeting to membrane, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Translation, organism-specific biosystem (from REACTOME)
Translation, organism-specific biosystemcomputationally inferred pathway (not manually curated)

Gene Ontology Provided by FlyBase

Function	Evidence Code	Pubs
structural constituent of ribosome	ISS Inferred from Sequence or Structural Similarity more info
structural constituent of ribosome	NAS Non-traceable Author Statement more info

Process	Evidence Code	Pubs
centrosome duplication	IMP Inferred from Mutant Phenotype more info
mitotic spindle elongation	IMP Inferred from Mutant Phenotype more info	PubMed
translation	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
cytosolic large ribosomal subunit	ISS Inferred from Sequence or Structural Similarity more info
ribosome	IDA Inferred from Direct Assay more info	PubMed
ribosome	NAS Non-traceable Author Statement more info

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General protein information

Preferred Names: CG2746 gene product from transcript CG2746-RA

Names: CG2746-PA; CG2746-PB; Minute(2)60E; RpL19-PA; RpL19-PB; enhancer of delta KP135; lethal (2) k03704; ribosomal protein L19

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NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NT_033778.3

Range

20855968..20857070, complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_057283.4 → NP_476631.1 ribosomal protein L19, isoform A [Drosophila melanogaster]

Status: REVIEWED

UniProtKB/Swiss-Prot

P36241

Related

FBpp0072312, FBtr0072405

Conserved Domains (1) summary

cd01417
Location:4 – 158
Blast Score: 486

Ribosomal_L19e_E; Ribosomal protein L19e, eukaryotic. L19e is found in the large ribosomal subunit of eukaryotes and archaea. L19e is distinct from the ribosomal subunit L19, which is found in prokaryotes. It consists of two small globular domains connected by an ...
NM_206219.1 → NP_995941.1 ribosomal protein L19, isoform B [Drosophila melanogaster]

Status: REVIEWED

UniProtKB/Swiss-Prot

P36241

Related

FBpp0089141, FBtr0072406

Conserved Domains (1) summary

cd01417
Location:4 – 158
Blast Score: 486

Ribosomal_L19e_E; Ribosomal protein L19e, eukaryotic. L19e is found in the large ribosomal subunit of eukaryotes and archaea. L19e is distinct from the ribosomal subunit L19, which is found in prokaryotes. It consists of two small globular domains connected by an ...