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    bs blistered [ Drosophila melanogaster ]

    Gene ID: 37890, updated on 10-May-2012
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    Summary

    Official Symbol
    bsprovided by Flybase
    Official Full Name
    blisteredprovided by Flybase
    Primary source
    FLYBASE:FBgn0004101
    Locus tag
    Dmel_CG3411
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    ba; Bs; BS; bs/Dsrf; bs/DSRF; CG3411; D-SRF; Dmel\CG3411; DmSRF; dsrf; dSRF; DSrf; DSRF; DSrf/bs; Group IIc; l(2)03267; Mal; pruned/DSRF; px; Serf; Srf; SRF
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    Genomic context

    Location :
    60C6-60C7; 2-107.3 cM
    Sequence :
    Chromosome: 2R; NT_033778.3 (20231236..20263998)
    See bs in Epigenomics, MapViewer

    Chromosome 2R - NT_033778.3Genomic Context describing neighboring genes Neighboring gene beta-Tubulin at 60D Neighboring gene slow border cells Neighboring gene transfer RNA:asn5:60C Neighboring gene muscarinic Acetylcholine Receptor 60C Neighboring gene CG13578 gene product from transcript CG13578-RA Neighboring gene Sterile20-like kinase

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. A protein complex network of Drosophila melanogaster. Guruharsha KG, et al. Cell, 2011 Oct 28. PMID 22036573.
    2. Negative modulation of bone morphogenetic protein signaling by Dullard during wing vein formation in Drosophila. Liu Z, et al. Dev Growth Differ, 2011 Aug. PMID 21790556.
    3. The Drosophila homologue of SRF acts as a boosting mechanism to sustain FGF-induced terminal branching in the tracheal system. Gervais L, et al. Development, 2011 Apr. PMID 21385762.
    4. The effects of weak genetic perturbations on the transcriptome of the wing imaginal disc and its association with wing shape in Drosophila melanogaster. Dworkin I, et al. Genetics, 2011 Apr. PMID 21288875.
    5. Two-color in vivo imaging of photoreceptor apoptosis and development in Drosophila. Gambis A, et al. Dev Biol, 2011 Mar 1. PMID 21215264.

    See all (155) citations in PubMed

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. Our results indicate that DSRF acts as an amplifying step to sustain the progression of terminal branch elongation of the trachael system
      Title: The Drosophila homologue of SRF acts as a boosting mechanism to sustain FGF-induced terminal branching in the tracheal system.
    2. Border cell migration requires the activity of serum response factor and nuclear accumulation of MAL-D is induced by cell stretching.
      Title: Evidence for tension-based regulation of Drosophila MAL and SRF during invasive cell migration.
    3. Data describe a myocardin-related transcription factor from Drosophila, DMRTF, which is shares homology with mammalian myocardin and MRTFs and stimulates the activity of Drosophila serum response factor.
      Title: A myocardin-related transcription factor regulates activity of serum response factor in Drosophila.
    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:63464 BioGRID:58020 Act5C    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:63464 BioGRID:67310 Dl    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:63464 BioGRID:63083 Egfr    BioGRID  PubMed Phenotypic Suppression 
    BioGRID:63464 BioGRID:61596 Gapdh1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:63464 BioGRID:67421 H    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:63464 BioGRID:59275 Mer    BioGRID  PubMed Phenotypic Enhancement; Phenotypic Suppression 
    BioGRID:63464 BioGRID:57823 N    BioGRID  PubMed Phenotypic Enhancement; Phenotypic Suppression 
    BioGRID:63464 BioGRID:66301 Ras85D    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:63464 BioGRID:69557 csw    BioGRID  PubMed Phenotypic Suppression 
    BioGRID:63464 BioGRID:63646 emc    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:63464 BioGRID:58994 if    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:63464 BioGRID:58660 mew    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:63464 BioGRID:69357 mys    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:63464 BioGRID:63189 px    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:63464 BioGRID:63708 rho    BioGRID  PubMed Phenotypic Enhancement; Phenotypic Suppression 
    BioGRID:63464 BioGRID:78013 rl    BioGRID  PubMed Phenotypic Enhancement; Phenotypic Suppression 
    BioGRID:63464 BioGRID:64117 vn    BioGRID  PubMed Phenotypic Suppression 
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    General gene information

    Markers

    mobile_element

    • Loc: 20241007-20249310 mobile_element_type = transposon:roo{}883

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    contributes_to RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    activating transcription factor binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    apposition of dorsal and ventral imaginal disc-derived wing surfaces IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    cell fate commitment TAS
    Traceable Author Statement
    more info
    		 PubMed 
    imaginal disc-derived wing morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    imaginal disc-derived wing morphogenesis NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    imaginal disc-derived wing morphogenesis TAS
    Traceable Author Statement
    more info
    		 PubMed 
    imaginal disc-derived wing vein morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    open tracheal system development IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    open tracheal system development NAS
    Non-traceable Author Statement
    more info
    		  
    open tracheal system development TAS
    Traceable Author Statement
    more info
    		 PubMed 
    positive regulation of transcription from RNA polymerase II promoter IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    sleep IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    terminal branching, open tracheal system IMP
    Inferred from Mutant Phenotype
    more info
    		  
    terminal branching, open tracheal system NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    terminal branching, open tracheal system TAS
    Traceable Author Statement
    more info
    		 PubMed 
    terminal cell fate specification, open tracheal system TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    nucleus NAS
    Non-traceable Author Statement
    more info
    		  
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    General protein information

    Preferred Names
    CG3411 gene product from transcript CG3411-RA
    Names
    CG3411-PA
    CG3411-PB
    balloon
    blistered
    blistered/Drosophila serum response factor
    bs-PA
    bs-PB
    drosophila serum response factor
    pruned
    serum response factor
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.3

      Range
      20231236..20263998
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_166667.1 → NP_726438.1  blistered, isoform A [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q24535
      Related
      FBpp0072178, FBtr0072271
      Conserved Domains (1) summary
      cd00266
      Location:166 – 247
      Blast Score: 234
      MADS_SRF_like; SRF-like/Type I subfamily of MADS (MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero- and homo-dimers. Differs from the MEF-like/Type II subgroup mainly in ...

    2. NM_001144279.1 → NP_001137751.1  blistered, isoform B [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7YZQ0
      Related
      FBpp0288528, FBtr0290089
      Conserved Domains (1) summary
      cd00266
      Location:166 – 247
      Blast Score: 241
      MADS_SRF_like; SRF-like/Type I subfamily of MADS (MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero- and homo-dimers. Differs from the MEF-like/Type II subgroup mainly in ...
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    mRNA AY095071.1 AAM11399.1
    genomic AE013599.4 AAF47195.1
    genomic AE013599.4 ACL83204.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q24535.2 GenPept
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    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

      Supplemental Content