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    EBNA-LP EBNA-LP [ Human herpesvirus 4 ]

    Gene ID: 3783746, updated on 23-May-2012
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    Summary

    Gene symbol
    EBNA-LP
    Gene description
    EBNA-LP
    Locus tag
    HHV4_EBNA-LP
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Human herpesvirus 4 (strain: B95-8, strain: Raji, type: 1, common: Epstein-Barr virus, acronym: EBV, acronym: HHV-4, nat-host: Homo sapiens)
    Lineage
    Viruses; dsDNA viruses, no RNA stage; Herpesvirales; Herpesviridae; Gammaherpesvirinae; Lymphocryptovirus
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    Genomic context

    Sequence :
    NC_007605.1 (14352..37744)

    NC_007605.1Genomic Context describing neighboring genes Neighboring gene EBNA-3B Neighboring gene EBNA-3A Neighboring gene BCRF1 Neighboring gene EBNA-2 Neighboring gene EBNA-1 Neighboring gene BWRF1 Neighboring gene BWRF1 Neighboring gene BWRF1 Neighboring gene BWRF1 Neighboring gene BWRF1 Neighboring gene BWRF1 Neighboring gene BWRF1 Neighboring gene BWRF1 Neighboring gene BHLF1 Neighboring gene BHRF1

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. EBV nuclear antigen EBNALP dismisses transcription repressors NCoR and RBPJ from enhancers and EBNA2 increases NCoR-deficient RBPJ DNA binding. Portal D, et al. Proc Natl Acad Sci U S A, 2011 May 10. PMID 21518914.
    2. Nuclear-cytoplasmic shuttling is not required for the Epstein-Barr virus EBNA-LP transcriptional coactivation function. Ling PD, et al. J Virol, 2009 Jul. PMID 19403674.
    3. Identification of intracellular proteins associated with the EBV-encoded nuclear antigen 5 using an efficient TAP procedure and FT-ICR mass spectrometry. Forsman A, et al. J Proteome Res, 2008 Jun. PMID 18457437.
    4. Epstein-Barr nuclear antigen leader protein coactivates transcription through interaction with histone deacetylase 4. Portal D, et al. Proc Natl Acad Sci U S A, 2006 Dec 19. PMID 17159145.
    5. Updated Epstein-Barr virus (EBV) DNA sequence and analysis of a promoter for the BART (CST, BARF0) RNAs of EBV. de Jesus O, et al. J Gen Virol, 2003 Jun. PMID 12771413.

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. data strongly support a model in which EBNA2 association with NCoR-deficient RBPJ enhances transcription and EBNALP dismisses NCoR and RBPJ repressive complexes from enhancers
      Title: EBV nuclear antigen EBNALP dismisses transcription repressors NCoR and RBPJ from enhancers and EBNA2 increases NCoR-deficient RBPJ DNA binding.
    2. Nuclear-cytoplasmic shuttling is not required for efficient EBNA-LP coactivation function.
      Title: Nuclear-cytoplasmic shuttling is not required for the Epstein-Barr virus EBNA-LP transcriptional coactivation function.
    3. Epstein-Barr nuclear antigen leader protein coactivates transcription through interaction with histone deacetylase 4.
      Title: Epstein-Barr nuclear antigen leader protein coactivates transcription through interaction with histone deacetylase 4.
    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:971788 BioGRID:106575 ACTB    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:117940 AKAP8L    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:113645 ALDH5A1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:106987 ATP5A1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:114908 BAG2    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Co-purification 
    BioGRID:971788 BioGRID:114907 BAG3    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:971788 BioGRID:107243 CAD    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:107267 CAMK2D    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:107279 CAPZA1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:107282 CAPZB    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:107420 CDK1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:116056 CLPX    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:107623 CLTC    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:107821 CSE1L    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:107984 DARS    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:115776 DDX17    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:108021 DDX5    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:971788 BioGRID:108025 DHX9    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:109569 DNAJB1    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:971788 BioGRID:117350 DNAJB5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:115360 DNAJB6    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:108285 EIF2S1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:114211 EIF3B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:108372 EPRS    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:120362 FKBP14    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:108607 FLNC    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:108901 GBAS    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:108914 GCHFR    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:116181 GCN1L1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:109008 GLUD1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:123210 GRPEL1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:114461 H1FX    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:115719 HAX1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:109262 HIST1H1D    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:113935 HIST1H2BG    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:116149 HNRNPA0    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:109420 HNRNPA1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:109422 HNRNPA2B1    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:971788 BioGRID:109423 HNRNPAB    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:131227 HNRNPCL1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:109425 HNRNPD    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:109431 HNRNPK    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:971788 BioGRID:110751 HNRNPM    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:971788 BioGRID:115530 HNRNPR    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:109433 HNRNPU    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:109552 HSP90AA1    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:971788 BioGRID:109540 HSPA4    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Co-purification 
    BioGRID:971788 BioGRID:109541 HSPA5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:109544 HSPA8    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Co-purification 
    BioGRID:971788 BioGRID:109547 HSPB1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:109561 HSPD1    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:971788 BioGRID:109605 IARS    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:109645 IDH3A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:109646 IDH3B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:109822 ILF3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:116004 IQGAP2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:115900 KHDRBS1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:110137 LDHB    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:115432 LRPPRC    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:114879 MAGED1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:110257 MARCKS    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:122050 MCCC2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:113752 MLF2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:110771 NCL    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:971788 BioGRID:114080 NIPSNAP1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:110894 NME1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:110904 NONO    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:971788 BioGRID:115041 NUP93    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:111072 P4HA1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:114464 P4HA2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:111126 PCBP1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:111127 PCBP2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:111128 PCCA    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:111129 PCCB    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:116459 PHB2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:115842 PRPF8    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:111667 PSMB6    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:111674 PSMC2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:111681 PSMD2    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:971788 BioGRID:111697 PTBP1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:118962 PYCR2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:111797 QARS    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:115417 RAD50    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:111863 RBBP4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:111866 RBBP7    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:111887 RCN1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:111888 RCN2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:111915 RFC3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:112054 RPL10    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:112055 RPL11    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:112056 RPL12    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:112057 RPL13    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:112059 RPL17    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:112061 RPL18    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:112066 RPL22    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:114752 RPL23    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:112071 RPL24    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:112073 RPL26    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:112076 RPL27A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:112079 RPL31    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:112083 RPL34    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:112049 RPL7    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:112050 RPL7A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:112052 RPL8    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:112053 RPL9    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:112119 RPS11    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:112121 RPS13    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:112122 RPS14    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:112123 RPS15    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:112131 RPS16    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:112132 RPS17    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:112136 RPS18    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:112101 RPS2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:112142 RPS23    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:112144 RPS25    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:119256 RPS27L    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:112103 RPS3A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:112105 RPS4X    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:112108 RPS6    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:112116 RPS8    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:112117 RPS9    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:117587 RSL1D1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:114166 RUVBL1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:116067 RUVBL2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:112296 SEC13    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:115247 SEC16A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:117571 SERBP1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:112316 SET    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:117017 SF3B1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:116188 SF3B2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:112319 SFPQ    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:971788 BioGRID:106789 SLC25A5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:106790 SLC25A6    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:116661 SNRNP200    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:112510 SNRPA    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:112513 SNRPB2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:112517 SNRPD2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:112324 SRSF1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:112620 SSBP1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:115563 STUB1    BioGRID  PubMed Co-fractionation 
    BioGRID:971788 BioGRID:115755 SYNCRIP    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:124961 TIMM50    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:116169 TMED10    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:120115 TMED9    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:115651 TUBA1B    BioGRID  PubMed Affinity Capture-Western; Co-purification 
    BioGRID:971788 BioGRID:128444 TUBB    BioGRID  PubMed Affinity Capture-Western; Co-purification 
    BioGRID:971788 BioGRID:119501 UBR5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:113224 UPP1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:122532 WDR77    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:116420 XPOT    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:971788 BioGRID:113353 XRCC5    BioGRID  PubMed Affinity Capture-MS 
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    General gene information

    TATA_signal

    • Loc: 14352-14357
    • Loc: 17424-17429
    • Loc: 20496-20501
    • Loc: 23568-23573
    • Loc: 26640-26645
    • Loc: 29712-29717
    • Loc: 32784-32789

    polyA_signal

    • Loc: 37715-37720

    Repeated regions

    • Loc: 15073-18144 rpt_family = IR1; W , rpt_type = direct
    • Loc: 18145-21216 rpt_family = IR1; W , rpt_type = direct
    • Loc: 21217-24288 rpt_family = IR1; W , rpt_type = direct
    • Loc: 24289-27360 rpt_family = IR1; W , rpt_type = direct
    • Loc: 27361-30432 rpt_family = IR1; W , rpt_type = direct
    • Loc: 30433-33504 rpt_family = IR1; W , rpt_type = direct
    • Loc: 33505-35355 rpt_family = IR1; W , rpt_type = direct
    • Loc: 36390-36512 rpt_unit_range = 36390..36398
    • Loc: 37237-37290 rpt_unit_range = 37237..37242
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    General protein information

    Names
    EBNA-LP
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    mRNA and Protein(s)

    1. YP_401636.1 EBNA-LP [Human herpesvirus 4]

      UniProtKB/Swiss-Prot
      P0C732
      UniProtKB/Swiss-Prot
      Q8AZK7
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AJ507799.2 CAD53387.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    P0C732.1 GenPept
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    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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