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    Chi Chip [ Drosophila melanogaster ]

    Gene ID: 37837, updated on 10-May-2012
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    Summary

    Official Symbol
    Chiprovided by Flybase
    Official Full Name
    Chipprovided by Flybase
    Primary source
    FLYBASE:FBgn0013764
    Locus tag
    Dmel_CG3924
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG3924; chip; CHIP; dLdb; dLDB/Chip; Dmel\CG3924; l(2)04405; l(2)k04405; Ldb; LDB
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    Genomic context

    Location :
    60B5-60B5; 2-106.8 cM
    Sequence :
    Chromosome: 2R; NT_033778.3 (19919062..19921459, complement)
    See Chi in Epigenomics, MapViewer

    Chromosome 2R - NT_033778.3Genomic Context describing neighboring genes Neighboring gene CG3163 gene product from transcript CG3163-RA Neighboring gene CG30172 gene product from transcript CG30172-RA Neighboring gene CG3167 gene product from transcript CG3167-RA Neighboring gene CG13567 gene product from transcript CG13567-RB

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. A protein complex network of Drosophila melanogaster. Guruharsha KG, et al. Cell, 2011 Oct 28. PMID 22036573.
    2. A targeted genetic screen identifies crucial players in the specification of the Drosophila abdominal Capaergic neurons. Gabilondo H, et al. Mech Dev, 2011 Mar-Apr. PMID 21236339.
    3. Transcriptional regulation by CHIP/LDB complexes. Bronstein R, et al. PLoS Genet, 2010 Aug 12. PMID 20730086.
    4. The pronotum LIM-HD gene tailup is both a positive and a negative regulator of the proneural genes achaete and scute of Drosophila. de Navascués J, et al. Mech Dev, 2010 Sep-Dec. PMID 20580820.
    5. The transcriptional co-factor Chip acts with LIM-homeodomain proteins to set the boundary of the eye field in Drosophila. Roignant JY, et al. Development, 2010 Jan. PMID 20040493.

    See all (67) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. Chip is required for posteclosion behavior in Drosophila.
      Title: Chip is required for posteclosion behavior in Drosophila.
    2. Pannier and Chip play an essential role during repression of proneural gene expression.
      Title: Enhancer-promoter communication mediated by Chip during Pannier-driven proneural patterning is regulated by Osa.
    3. Chip-mediated partnerships of the homeodomain proteins Bar and Aristaless with the LIM-HOM proteins Apterous and Lim1 regulate distal leg development
      Title: Chip-mediated partnerships of the homeodomain proteins Bar and Aristaless with the LIM-HOM proteins Apterous and Lim1 regulate distal leg development.
    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:63418 BioGRID:59159 Bx    BioGRID  PubMed Affinity Capture-MS; Phenotypic Enhancement; Phenotypic Suppression 
    BioGRID:63418 BioGRID:64760 CG10418    BioGRID  PubMed Two-hybrid 
    BioGRID:63418 BioGRID:61615 CG11165    BioGRID  PubMed Two-hybrid 
    BioGRID:63418 BioGRID:63151 CG11275    BioGRID  PubMed Two-hybrid 
    BioGRID:63418 BioGRID:66008 CG15177    BioGRID  PubMed Two-hybrid 
    BioGRID:63418 BioGRID:72662 CG15578    BioGRID  PubMed Two-hybrid 
    BioGRID:63418 BioGRID:72488 CG17450    BioGRID  PubMed Two-hybrid 
    BioGRID:63418 BioGRID:64759 CG32105    BioGRID  PubMed Two-hybrid 
    BioGRID:63418 BioGRID:76824 CG32819    BioGRID  PubMed Two-hybrid 
    BioGRID:63418 BioGRID:76825 CG32820    BioGRID  PubMed Two-hybrid 
    BioGRID:63418 BioGRID:64758 CG4328    BioGRID  PubMed Two-hybrid 
    BioGRID:63418 BioGRID:66450 CG4570    BioGRID  PubMed Two-hybrid 
    BioGRID:63418 BioGRID:67373 CG4836    BioGRID  PubMed Two-hybrid 
    BioGRID:63418 BioGRID:65502 CG5618    BioGRID  PubMed Two-hybrid 
    BioGRID:63418 BioGRID:60452 CG5708    BioGRID  PubMed Two-hybrid 
    BioGRID:63418 BioGRID:61671 Lcp2    BioGRID  PubMed Two-hybrid 
    BioGRID:63418 BioGRID:58272 Lim1    BioGRID  PubMed Two-hybrid 
    BioGRID:63418 BioGRID:61171 Lim3    BioGRID  PubMed Two-hybrid 
    BioGRID:63418 BioGRID:57823 N    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:63418 BioGRID:78269 RpL38    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:63418 BioGRID:67060 Scp2    BioGRID  PubMed Two-hybrid 
    BioGRID:63418 BioGRID:67198 Ssdp    BioGRID  PubMed Affinity Capture-MS; Phenotypic Enhancement; Two-hybrid 
    BioGRID:63418 BioGRID:64113 Tektin-C    BioGRID  PubMed Two-hybrid 
    BioGRID:63418 BioGRID:67078 Ubx    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:63418 BioGRID:61416 ap    BioGRID  PubMed Phenotypic Enhancement; Phenotypic Suppression; Two-hybrid 
    BioGRID:63418 BioGRID:66028 bcd    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:63418 BioGRID:69119 ct    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:63418 BioGRID:69126 lola    BioGRID  PubMed Two-hybrid 
    BioGRID:63418 BioGRID:58742 mRpL38    BioGRID  PubMed Two-hybrid 
    BioGRID:63418 BioGRID:61552 p47    BioGRID  PubMed Two-hybrid 
    BioGRID:63418 BioGRID:69326 pnr    BioGRID  PubMed Phenotypic Enhancement; Phenotypic Suppression 
    BioGRID:63418 BioGRID:66816 su(Hw)    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:63418 BioGRID:61139 tup    BioGRID  PubMed Two-hybrid 
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    General gene information

    Homology

    • Homologs of the Chi gene: The Chi gene is conserved in human, chimpanzee, , dog, cow, mouse, rat, chicken, zebrafish, and mosquito.

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    RNA polymerase II transcription factor binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    transcription cofactor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    transcription factor binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    blastoderm segmentation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    chaeta development IMP
    Inferred from Mutant Phenotype
    more info
    		  
    chaeta morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    dendrite guidance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    imaginal disc-derived wing morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    nervous system development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    phagocytosis, engulfment IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    positive regulation of transcription, DNA-dependent IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    regulation of eclosion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    transcription, DNA-dependent IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
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    General protein information

    Preferred Names
    CG3924 gene product from transcript CG3924-RA
    Names
    CG3924-PA
    CG3924-PB
    Chi-PA
    Chi-PB
    chip
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.3

      Range
      19919062..19921459, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_057734.3 → NP_477082.1  chip, isoform A [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      O18353
      Related
      FBpp0072100, FBtr0072191
      Conserved Domains (2) summary
      pfam01803
      Location:217 – 422
      Blast Score: 582
      LIM_bind; LIM-domain binding protein
      pfam03153
      Location:43 – 93
      Blast Score: 92
      TFIIA; Transcription factor IIA, alpha/beta subunit

    2. NM_166650.1 → NP_726403.2  chip, isoform B [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7KVG9
      Related
      FBpp0072101, FBtr0072192
      Conserved Domains (2) summary
      pfam01803
      Location:236 – 441
      Blast Score: 582
      LIM_bind; LIM-domain binding protein
      pfam03153
      Location:62 – 112
      Blast Score: 92
      TFIIA; Transcription factor IIA, alpha/beta subunit
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    mRNA AY058561.1 AAL13790.1
    genomic AE013599.4 AAF47142.1
    genomic AF010325.1 AAB62574.1
    genomic AE013599.4 AAM68293.2
    mRNA BT125015.1 ADI46811.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    O18353.1 GenPept
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    Additional Links

    Gene LinkOut

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