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BIRC5 baculoviral IAP repeat containing 5 [ Gallus gallus (chicken) ]

Gene ID: 374078, updated on 2-Jun-2014
Symbol
BIRC5provided by CGNC
Full Name
baculoviral IAP repeat containing 5provided by CGNC
Primary source
CGNC:6615
See related
Ensembl:ENSGALG00000008713
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Testudines + Archosauria group; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
survivin
See BIRC5 in MapViewer
Location:
chromosome: 3
Exon count:
3
Annotation release Status Assembly Chr Location
102 current Gallus_gallus-4.0 (GCF_000002315.3) 3 NC_006090.3 (14764584..14765717, complement)

Chromosome 3 - NC_006090.3Genomic Context describing neighboring genes Neighboring gene polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa Neighboring gene double zinc ribbon and ankyrin repeat domains 1 Neighboring gene CSRP2 binding protein Neighboring gene uncharacterized LOC101749665

Genomic Sequence:
NC_006090.3 chromosome 3 reference Gallus_gallus-4.0 Primary Assembly

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • Apoptosis, organism-specific biosystem (from WikiPathways)
    Apoptosis, organism-specific biosystemApoptosis is a distinct form of cell death that is functionally and morphologically different from necrosis. Nuclear chromatin condensation, cytoplasmic shrinking, dilated endoplasmic reticulum, and ...

Homology

Preferred Names
survivin
Names
survivin
baculoviral IAP repeat-containing 5 (survivin)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012318.1NP_001012318.1  survivin isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1).
    Source sequence(s)
    AF322051, BU135446, BU355446, BX275001, CN227820
    UniProtKB/TrEMBL
    F1NN48
    UniProtKB/TrEMBL
    Q9DDK0
    Related
    ENSGALP00000038330, ENSGALT00000039119
    Conserved Domains (1) summary
    cd00022
    Location:2088
    Blast Score: 241
    BIR; Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes. ...
  2. NM_001012319.1NP_001012319.1  survivin isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) has an alternate segment in the 3' coding region and UTR, compared to variant 1. The resulting protein (isoform 2) is shorter and has a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AF377323, BU135446, BU355446, BX275001, CN227820
    UniProtKB/TrEMBL
    Q90ZN0
    Conserved Domains (1) summary
    cd00022
    Location:2088
    Blast Score: 238
    BIR; Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes. ...
  3. NM_204235.2NP_989566.1  survivin isoform 3

    See proteins identical to NP_989566.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an alternate in-frame exon that results in a frameshift and has an alternate segment in the 3' UTR, compared to variant 1. The resulting protein (isoform 3) is shorter than isoform 1. This variant is supported by transcript evidence but there is no experimental evidence for the product of this transcript.
    Source sequence(s)
    AF377324, BU135446, BX275001, CN227820
    UniProtKB/TrEMBL
    Q90VY6

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 102

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Gallus_gallus-4.0 Primary Assembly

Genomic

  1. NC_006090.3 

    Range
    14764584..14765717
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001012317.1: Suppressed sequence

    Description
    NM_001012317.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.