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ctbp1.L C-terminal binding protein 1 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 373701, updated on 11-Apr-2024

Summary

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Official Symbol
ctbp1.L
Official Full Name
C-terminal binding protein 1 L homeolog
Primary source
Xenbase:XB-GENE-864974
Locus tag
XELAEV_18005017mg
See related
EnsemblRapid:ENSXLAG00005020859
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
CtBP; ctbp1; ctbp-a; xctbp1; ctbp1-A
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Genomic context

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Location:
chromosome: 1L
Exon count:
16
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 1L NC_054371.1 (19811250..20173479, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 1L NC_030724.1 (11013898..11155449, complement)

Chromosome 1L - NC_054371.1Genomic Context describing neighboring genes Neighboring gene transmembrane emp24 domain-containing protein 11-like Neighboring gene spondin 2, extracellular matrix protein L homeolog Neighboring gene uncharacterized LOC108696303 Neighboring gene macrophage erythroblast attacher L homeolog Neighboring gene UV stimulated scaffold protein A L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. C-Terminal binding protein is a transcriptional repressor that interacts with a specific class of vertebrate Polycomb proteins. Sewalt RG, et al. Mol Cell Biol, 1999 Jan. PMID 9858600, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables DNA-binding transcription factor binding IEA
Inferred from Electronic Annotation
more info
  
enables NAD binding IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
Inferred from Electronic Annotation
more info
  
enables transcription coactivator activity IEA
Inferred from Electronic Annotation
more info
  
enables transcription coregulator binding IEA
Inferred from Electronic Annotation
more info
  
enables transcription corepressor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within negative regulation of DNA-templated transcription ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
C-terminal-binding protein 1
Names
C-terminal-binding protein A
NP_001079151.1
XP_018110185.1
XP_018110345.1
XP_041442837.1
XP_041442870.1
XP_041443001.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001085682.1 → NP_001079151.1  C-terminal-binding protein 1

    See identical proteins and their annotated locations for NP_001079151.1

    Status: PROVISIONAL

    Source sequence(s)
    AF091554
    UniProtKB/Swiss-Prot
    Q9YHU0
    Related
    ENSXLAP00005061275.1, ENSXLAT00005062727.1
    Conserved Domains (2) summary
    COG0111
    Location:55 → 354
    SerA; Phosphoglycerate dehydrogenase or related dehydrogenase [Coenzyme transport and metabolism, General function prediction only]
    cd05299
    Location:28 → 346
    CtBP_dh; C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054371.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    19811250..20173479 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041586903.1 → XP_041442837.1  C-terminal-binding protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8J1MM82
    Related
    ENSXLAP00005061296.1, ENSXLAT00005062747.1
    Conserved Domains (1) summary
    cd05299
    Location:67 → 385
    CtBP_dh; C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor

  2. XM_018254856.2 → XP_018110345.1  C-terminal-binding protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8J0UVK5
    Related
    ENSXLAP00005061286.1, ENSXLAT00005062738.1

  3. XM_018254696.2 → XP_018110185.1  C-terminal-binding protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A1L8HT10, A0A974I2R3
    Conserved Domains (1) summary
    cd05299
    Location:29 → 347
    CtBP_dh; C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor

  4. XM_041586936.1 → XP_041442870.1  C-terminal-binding protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A1L8HT10, A0A974I2R3
    Related
    ENSXLAP00005061267.1, ENSXLAT00005062719.1
    Conserved Domains (1) summary
    cd05299
    Location:29 → 347
    CtBP_dh; C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor

  5. XM_041587067.1 → XP_041443001.1  C-terminal-binding protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A8J1MNJ3
    Conserved Domains (1) summary
    cd05299
    Location:67 → 385
    CtBP_dh; C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9YHU0.1 GenPept UniProtKB/Swiss-Prot:Q9YHU0

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