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    nopo no poles [ Drosophila melanogaster ]

    Gene ID: 37083, updated on 9-May-2012
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    Summary

    Official Symbol
    nopoprovided by Flybase
    Official Full Name
    no polesprovided by Flybase
    Primary source
    FLYBASE:FBgn0034314
    Locus tag
    Dmel_CG5140
    Gene type
    protein coding
    RNA name
    no poles
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG5140; Dmel\CG5140; Nopo; TRIP
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    Genomic context

    Location :
    55B12-55B12
    Sequence :
    Chromosome: 2R; NT_033778.3 (14068001..14070024)
    See nopo in Epigenomics, MapViewer

    Chromosome 2R - NT_033778.3Genomic Context describing neighboring genes Neighboring gene CG10916 gene product from transcript CG10916-RA Neighboring gene CG5726 gene product from transcript CG5726-RA Neighboring gene CG5721 gene product from transcript CG5721-RA Neighboring gene CG33958 gene product from transcript CG33958-RA Neighboring gene pseudo Neighboring gene CG14500 gene product from transcript CG14500-RA

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. no poles encodes a predicted E3 ubiquitin ligase required for early embryonic development of Drosophila. Merkle JA, et al. Development, 2009 Feb. PMID 19141674.
    2. alpha-Endosulfine is a conserved protein required for oocyte meiotic maturation in Drosophila. Von Stetina JR, et al. Development, 2008 Nov. PMID 18927152.
    3. Sequence finishing and mapping of Drosophila melanogaster heterochromatin. Hoskins RA, et al. Science, 2007 Jun 15. PMID 17569867.
    4. The Release 5.1 annotation of Drosophila melanogaster heterochromatin. Smith CD, et al. Science, 2007 Jun 15. PMID 17569856.
    5. Combined evidence annotation of transposable elements in genome sequences. Quesneville H, et al. PLoS Comput Biol, 2005 Jul. PMID 16110336.

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. an E2-E3 ubiquitination complex consisting of BEN-UEV1A (E2 heterodimer) and NOPO (E3 ligase) is required for the preservation of genomic integrity during early embryogenesis.
      Title: no poles encodes a predicted E3 ubiquitin ligase required for early embryonic development of Drosophila.
    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:62764 BioGRID:60093 CG11327    BioGRID  PubMed Two-hybrid 
    BioGRID:62764 BioGRID:60736 CG12404    BioGRID  PubMed Two-hybrid 
    BioGRID:62764 BioGRID:60412 CG13125    BioGRID  PubMed Two-hybrid 
    BioGRID:62764 BioGRID:67866 CG13627    BioGRID  PubMed Two-hybrid 
    BioGRID:62764 BioGRID:61754 CG13742    BioGRID  PubMed Two-hybrid 
    BioGRID:62764 BioGRID:61789 CG1968    BioGRID  PubMed Two-hybrid 
    BioGRID:62764 BioGRID:60126 CG3430    BioGRID  PubMed Two-hybrid 
    BioGRID:62764 BioGRID:67097 CG3995    BioGRID  PubMed Two-hybrid 
    BioGRID:62764 BioGRID:57711 CG4325    BioGRID  PubMed Two-hybrid 
    BioGRID:62764 BioGRID:62590 CG5522    BioGRID  PubMed Two-hybrid 
    BioGRID:62764 BioGRID:59942 CG7371    BioGRID  PubMed Two-hybrid 
    BioGRID:62764 BioGRID:66201 CG8032    BioGRID  PubMed Two-hybrid 
    BioGRID:62764 BioGRID:71397 Dip-B    BioGRID  PubMed Two-hybrid 
    BioGRID:62764 BioGRID:58239 Es2    BioGRID  PubMed Two-hybrid 
    BioGRID:62764 BioGRID:67780 Miro    BioGRID  PubMed Two-hybrid 
    BioGRID:62764 BioGRID:63689 Rac1    BioGRID  PubMed Two-hybrid 
    BioGRID:62764 BioGRID:58951 Traf-like    BioGRID  PubMed Two-hybrid 
    BioGRID:62764 BioGRID:59522 aru    BioGRID  PubMed Two-hybrid 
    BioGRID:62764 BioGRID:58728 ben    BioGRID  PubMed Two-hybrid 
    BioGRID:62764 BioGRID:57745 crn    BioGRID  PubMed Two-hybrid 
    BioGRID:62764 BioGRID:64252 eco    BioGRID  PubMed Two-hybrid 
    BioGRID:62764 BioGRID:57548 ewg    BioGRID  PubMed Two-hybrid 
    BioGRID:62764 BioGRID:64907 nuf    BioGRID  PubMed Two-hybrid 
    BioGRID:62764 BioGRID:72799 raps    BioGRID  PubMed Two-hybrid 
    BioGRID:62764 BioGRID:61272 rtGEF    BioGRID  PubMed Two-hybrid 
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    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    chromosome organization NAS
    Non-traceable Author Statement
    more info
    		  
    defense response ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    regulation of mitotic cell cycle IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    signal transduction ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
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    General protein information

    Preferred Names
    CG5140 gene product from transcript CG5140-RA
    Names
    CG5140-PA
    no poles
    nopo-PA
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.3

      Range
      14068001..14070024
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137461.3 → NP_611305.1  no poles [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K2X1
      Related
      FBpp0085929, FBtr0086750
      Conserved Domains (2) summary
      cd00162
      Location:6 – 50
      Blast Score: 135
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      pfam13923
      Location:3 – 47
      Blast Score: 140
      zf-C3HC4_2; Zinc finger, C3HC4 type (RING finger)
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    mRNA AY060610.1 AAL28158.1
    genomic AE013599.4 AAF57730.2
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9V8D7.1 GenPept
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    Additional Links

    Gene LinkOut

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