My NCBISign In

Display Settings:

Format

Send to:

Choose Destination

    Nup75 Nucleoporin 75 [ Drosophila melanogaster ]

    Gene ID: 37078, updated on 10-May-2012
    Help top of page

    Summary

    Official Symbol
    Nup75provided by Flybase
    Official Full Name
    Nucleoporin 75provided by Flybase
    Primary source
    FLYBASE:FBgn0034310
    Locus tag
    Dmel_CG5733
    Gene type
    protein coding
    RNA name
    nucleoporin 75
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG5733; Dmel\CG5733; Nup 75; nup75
    Help top of page

    Genomic context

    Location :
    55B10-55B11
    Sequence :
    Chromosome: 2R; NT_033778.3 (14052193..14054634, complement)
    See Nup75 in Epigenomics, MapViewer

    Chromosome 2R - NT_033778.3Genomic Context describing neighboring genes Neighboring gene CG10914 gene product from transcript CG10914-RA Neighboring gene CG10915 gene product from transcript CG10915-RA Neighboring gene CG42518 gene product from transcript CG42518-RB Neighboring gene Mediator complex subunit 9 Neighboring gene CG5729 gene product from transcript CG5729-RA

    Help top of page

    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
    Helptop of page

    Bibliography

    Related articles in PubMed

    1. Proteomics approach to study the functions of Drosophila myosin VI through identification of multiple cargo-binding proteins. Finan D, et al. Proc Natl Acad Sci U S A, 2011 Apr 5. PMID 21368190.
    2. Specific nucleoporin requirement for Smad nuclear translocation. Chen X, et al. Mol Cell Biol, 2010 Aug. PMID 20547758.
    3. A novel method to detect proteins evolving at correlated rates: identifying new functional relationships between coevolving proteins. Clark NL, et al. Mol Biol Evol, 2010 May. PMID 20044587.
    4. Sequence finishing and mapping of Drosophila melanogaster heterochromatin. Hoskins RA, et al. Science, 2007 Jun 15. PMID 17569867.
    5. The Release 5.1 annotation of Drosophila melanogaster heterochromatin. Smith CD, et al. Science, 2007 Jun 15. PMID 17569856.

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
    Help top of page

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:62759 BioGRID:59096 CG12985    BioGRID  PubMed Two-hybrid 
    BioGRID:62759 BioGRID:58851 CG15646    BioGRID  PubMed Two-hybrid 
    BioGRID:62759 BioGRID:67436 CG17271    BioGRID  PubMed Two-hybrid 
    BioGRID:62759 BioGRID:63761 CG2021    BioGRID  PubMed Two-hybrid 
    BioGRID:62759 BioGRID:59856 CG3355    BioGRID  PubMed Two-hybrid 
    BioGRID:62759 BioGRID:62597 CG6426    BioGRID  PubMed Two-hybrid 
    BioGRID:62759 BioGRID:60268 CG7787    BioGRID  PubMed Two-hybrid 
    BioGRID:62759 BioGRID:60230 Cka    BioGRID  PubMed Two-hybrid 
    BioGRID:62759 BioGRID:61474 Mob4    BioGRID  PubMed Two-hybrid 
    BioGRID:62759 BioGRID:60980 cact    BioGRID  PubMed Two-hybrid 
    BioGRID:62759 BioGRID:62905 hpo    BioGRID  PubMed Two-hybrid 
    BioGRID:62759 BioGRID:57724 ph-p    BioGRID  PubMed Two-hybrid 
    Help top of page

    General gene information

    Pathways from BioSystems

    • Nuclear pore complex, organism-specific biosystem (from KEGG)
      Nuclear pore complex, organism-specific biosystemStructural complex; Genetic information processing; RNA processing
    • RNA transport, organism-specific biosystem (from KEGG)
      RNA transport, organism-specific biosystemRNA transport from the nucleus to the cytoplasm is fundamental for gene expression. The different RNA species that are produced in the nucleus are exported through the nuclear pore complexes (NPCs) ...
    • RNA transport, conserved biosystem (from KEGG)
      RNA transport, conserved biosystemRNA transport from the nucleus to the cytoplasm is fundamental for gene expression. The different RNA species that are produced in the nucleus are exported through the nuclear pore complexes (NPCs) ...

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    NOT NLS-bearing substrate import into nucleus IMP
    Inferred from Mutant Phenotype
    more info
    		  
    SMAD protein import into nucleus IMP
    Inferred from Mutant Phenotype
    more info
    		  
    Help top of page

    General protein information

    Preferred Names
    CG5733 gene product from transcript CG5733-RA
    Names
    CG5733-PA
    Nup75-PA
    nucleoporin 75
    Help top of page

    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.3

      Range
      14052193..14054634, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137456.2 → NP_611300.2  nucleoporin 75 [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1YK02
      Related
      FBpp0085954, FBtr0086775
      Conserved Domains (1) summary
      pfam07575
      Location:57 – 612
      Blast Score: 1615
      Nucleopor_Nup85; Nup85 Nucleoporin
    Help top of page

    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AE013599.4 AAF57735.1
    genomic EF057925.1 ABL84860.1
    genomic EF057927.1 ABL84862.1
    genomic EF057933.1 ABL84868.1
    genomic EF057928.1 ABL84863.1
    genomic EF057932.1 ABL84867.1
    genomic EF057931.1 ABL84866.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9V8D2.1 GenPept
    Help top of page

    Additional Links

    Gene LinkOut

      Supplemental Content