RpLP2 Ribosomal protein LP2 [Drosophila melanogaster] - Gene

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Summary

Official Symbol: RpLP2provided by Flybase
Official Full Name: Ribosomal protein LP2provided by Flybase
Primary source: FLYBASE:FBgn0003274
Locus tag: Dmel_CG4918
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: BcDNA:SD22208; bs34h02.y1; CG4918; Dmel\CG4918; LP2; M(2)53; RLA2_DROME; rpA1; RpA1; RplP2; RpP1; T1; Tp1

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Genomic context

Location :: 53C9-53C9

Sequence :: Chromosome: 2R; NT_033778.3 (12473599..12474237)

See RpLP2 in Epigenomics, MapViewer

Chromosome 2R - NT_033778.3 Genomic Context describing neighboring genes

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Genomic regions, transcripts, and products

Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Go to reference sequence details

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Bibliography

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Submit: New GeneRIF Correction

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Interactions

Products	Interactant	Other Gene	Source	Pubs	Description
BioGRID:62568	BioGRID:66012	CG1307	BioGRID	PubMed	Two-hybrid
BioGRID:62568	BioGRID:62782	CG15067	BioGRID	PubMed	Two-hybrid
BioGRID:62568	BioGRID:60753	CG16972	BioGRID	PubMed	Two-hybrid
BioGRID:62568	BioGRID:66589	CG4810	BioGRID	PubMed	Two-hybrid
BioGRID:62568	BioGRID:62713	CG5009	BioGRID	PubMed	Two-hybrid
BioGRID:62568	BioGRID:66687	CG7518	BioGRID	PubMed	Two-hybrid
BioGRID:62568	BioGRID:62023	CG7763	BioGRID	PubMed	Two-hybrid
BioGRID:62568	BioGRID:68262	CG9986	BioGRID	PubMed	Two-hybrid
BioGRID:62568	BioGRID:66620	Cyp9f2	BioGRID	PubMed	Two-hybrid
BioGRID:62568	BioGRID:63773	R	BioGRID	PubMed	Two-hybrid
BioGRID:62568	BioGRID:64841	SNCF	BioGRID	PubMed	Two-hybrid
BioGRID:62568	BioGRID:65316	Sgf11	BioGRID	PubMed	Two-hybrid
BioGRID:62568	BioGRID:61494	Spn42Dc	BioGRID	PubMed	Two-hybrid
BioGRID:62568	BioGRID:64033	Tie	BioGRID	PubMed	Two-hybrid
BioGRID:62568	BioGRID:61043	dl	BioGRID	PubMed	Two-hybrid
BioGRID:62568	BioGRID:65326	ftz-f1	BioGRID	PubMed	Two-hybrid

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General gene information

Markers

Dm0864 (e-PCR)
- UniSTS:42351

Homology

Homologs of the RpLP2 gene: The RpLP2 gene is conserved in human, chimpanzee, , dog, cow, mouse, rat, chicken, zebrafish, mosquito, C.elegans, S.cerevisiae, K.lactis, , S.pombe, , and N.crassa.

Pathways from BioSystems

Cap-dependent Translation Initiation, organism-specific biosystem (from REACTOME)
Cap-dependent Translation Initiation, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Cytoplasmic Ribosomal Proteins, organism-specific biosystem (from WikiPathways)
Cytoplasmic Ribosomal Proteins, organism-specific biosystem
Cytoplasmic Ribosomal Proteins
Eukaryotic Translation Elongation, organism-specific biosystem (from REACTOME)
Eukaryotic Translation Elongation, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Eukaryotic Translation Initiation, organism-specific biosystem (from REACTOME)
Eukaryotic Translation Initiation, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Eukaryotic Translation Termination, organism-specific biosystem (from REACTOME)
Eukaryotic Translation Termination, organism-specific biosystemcomputationally inferred pathway (not manually curated)
GTP hydrolysis and joining of the 60S ribosomal subunit, organism-specific biosystem (from REACTOME)
GTP hydrolysis and joining of the 60S ribosomal subunit, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Gene Expression, organism-specific biosystem (from REACTOME)
Gene Expression, organism-specific biosystemcomputationally inferred pathway (not manually curated)
L13a-mediated translational silencing of Ceruloplasmin expression, organism-specific biosystem (from REACTOME)
L13a-mediated translational silencing of Ceruloplasmin expression, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Metabolism of proteins, organism-specific biosystem (from REACTOME)
Metabolism of proteins, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Peptide chain elongation, organism-specific biosystem (from REACTOME)
Peptide chain elongation, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Ribosome, organism-specific biosystem (from KEGG)
Ribosome, organism-specific biosystem
Ribosome
Ribosome, conserved biosystem (from KEGG)
Ribosome, conserved biosystem
Ribosome
Ribosome, eukaryotes, organism-specific biosystem (from KEGG)
Ribosome, eukaryotes, organism-specific biosystemStructural complex; Genetic information processing; Ribosome
SRP-dependent cotranslational protein targeting to membrane, organism-specific biosystem (from REACTOME)
SRP-dependent cotranslational protein targeting to membrane, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Translation, organism-specific biosystem (from REACTOME)
Translation, organism-specific biosystemcomputationally inferred pathway (not manually curated)

Gene Ontology Provided by FlyBase

Function	Evidence Code	Pubs
structural constituent of ribosome	ISS Inferred from Sequence or Structural Similarity more info
structural constituent of ribosome	NAS Non-traceable Author Statement more info

Process	Evidence Code	Pubs
translation	ISS Inferred from Sequence or Structural Similarity more info
translation	NAS Non-traceable Author Statement more info
translational elongation	IEA Inferred from Electronic Annotation more info
translational elongation	NAS Non-traceable Author Statement more info

Component	Evidence Code	Pubs
cytosolic large ribosomal subunit	NAS Non-traceable Author Statement more info
cytosolic ribosome	ISS Inferred from Sequence or Structural Similarity more info
cytosolic ribosome	NAS Non-traceable Author Statement more info
ribosome	IDA Inferred from Direct Assay more info	PubMed

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General protein information

Preferred Names: CG4918 gene product from transcript CG4918-RB

Names: CG4918-PA; CG4918-PB; RpLP2-PA; RpLP2-PB; Temporal-protein-1; ribosomal protein A1; ribosomal protein LP2; ribosomal protein P1; rpA1; temporal protein 1

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NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NT_033778.3

Range

12473599..12474237

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_206135.1 → NP_995857.1 ribosomal protein LP2, isoform B [Drosophila melanogaster]

Status: REVIEWED

UniProtKB/Swiss-Prot

P05389

Related

FBpp0089424, FBtr0087106

Conserved Domains (1) summary

cd05833
Location:1 – 65
Blast Score: 252

Ribosomal_P2; Ribosomal protein P2. This subfamily represents the eukaryotic large ribosomal protein P2. Eukaryotic P1 and P2 are functionally equivalent to the bacterial protein L7/L12, but are not homologous to L7/L12. P2 is located in the L12 stalk, with proteins ...
NM_079040.3 → NP_523764.1 ribosomal protein LP2, isoform A [Drosophila melanogaster]

Status: REVIEWED

UniProtKB/Swiss-Prot

P05389

Related

FBpp0086252, FBtr0087105

Conserved Domains (1) summary

cd05833
Location:1 – 65
Blast Score: 252

Ribosomal_P2; Ribosomal protein P2. This subfamily represents the eukaryotic large ribosomal protein P2. Eukaryotic P1 and P2 are functionally equivalent to the bacterial protein L7/L12, but are not homologous to L7/L12. P2 is located in the L12 stalk, with proteins ...