These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in this
section to the one reported in Genomic regions, transcripts, and products above.
Genomic
-
NG_027728.1 RefSeqGene
- Range
- 5001..24705
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001195286.1 → NP_001182215.1 interferon regulatory factor 4 isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) uses an alternate in-frame acceptor splice site at an internal coding exon compared to variant 1, resulting in an isoform (2) that is 1 aa shorter than isoform 1.
- Source sequence(s)
-
AL512308, AL589962, AW197089, BG230623, BM551611, CR977713, U52682, U63738
- UniProtKB/Swiss-Prot
-
Q15306
- Related
- ENSP00000398530, ENST00000412334
- Conserved Domains (2) summary
-
- cd00103
Location:23 – 129
Blast Score: 356
- IRF; Interferon Regulatory Factor (IRF); also known as tryptophan pentad repeat. The family of IRF transcription factors is important in the regulation of interferons in response to infection by virus and in the regulation of interferon-inducible genes. The ...
- pfam10401
Location:248 – 417
Blast Score: 598
- IRF-3; Interferon-regulatory factor 3
-
NM_002460.3 → NP_002451.2 interferon regulatory factor 4 isoform 1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes the longer isoform (1).
- Source sequence(s)
-
AL512308, AL589962, AW197089, BC015752, BG230623, BM551611, CR977713, U52682, U63738
- Consensus CDS
-
CCDS4469.1
- UniProtKB/Swiss-Prot
-
Q15306
- Related
- ENSP00000370343, OTTHUMP00000017905, ENST00000380956, OTTHUMT00000043638
- Conserved Domains (2) summary
-
- cd00103
Location:23 – 129
Blast Score: 357
- IRF; Interferon Regulatory Factor (IRF); also known as tryptophan pentad repeat. The family of IRF transcription factors is important in the regulation of interferons in response to infection by virus and in the regulation of interferon-inducible genes. The ...
- pfam10401
Location:249 – 418
Blast Score: 598
- IRF-3; Interferon-regulatory factor 3
RNA
-
NR_046000.1 RNA Sequence
- Description
- Transcript Variant: This variant (4) contains an alternate 3' splice pattern, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AL512308, AL589962, AW197089, BC015752, D78261, U52682
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs
for chromosomes and scaffolds (contigs) from both reference and alternate assemblies.
Model RNAs and proteins are also reported here.
Reference GRCh37.p5 Primary Assembly
Genomic
-
NC_000006.11 Reference GRCh37.p5 Primary Assembly
- Range
- 391739..411443
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate HuRef
Genomic
-
AC_000138.1 Alternate HuRef
- Range
- 264308..284078
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
The following Reference Sequences have been suppressed. Explain
These RefSeqs were suppressed for the cited
reason(s). Suppressed RefSeqs do not appear in BLAST databases, related sequence links,
or BLAST links (BLink), but may still be retrieved by clicking on their
accession.version below.
-
NR_036585.1: Suppressed sequence
- Description
- NR_036585.1: This RefSeq was permanently suppressed because currently there is support for the transcript.