Zscan25 zinc finger and SCAN domain containing 25 [Rattus norvegicus (Norway rat)] - Gene

Summary

Symbol: Zscan25provided by RGD
Full Name: zinc finger and SCAN domain containing 25provided by RGD
Primary source: RGD:1308619
See related: Ensembl:ENSRNOG00000042213 AllianceGenome:RGD:1308619
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Zfp498; Znf498
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Orthologous to human ZSCAN25 (zinc finger and SCAN domain containing 25). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Spleen (RPKM 31.5), Kidney (RPKM 24.4) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 12p11

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	12	NC_086030.1 (14441458..14451919, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	12	NC_051347.1 (9327347..9338206, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	12	NC_005111.4 (11774920..11785530, complement)

Chromosome 12 - NC_086030.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: zinc finger and SCAN domain-containing protein 25

Names: zinc finger and SCAN domain-containing protein 25 pseudogene; zinc finger protein 498

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001108851.1 → NP_001102321.1 zinc finger and SCAN domain-containing protein 25

See identical proteins and their annotated locations for NP_001102321.1

Status: PROVISIONAL

Source sequence(s)

CH474012

UniProtKB/TrEMBL

A6K1D9

Conserved Domains (6) summary

cd07765
Location:230 → 258

KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

COG5048
Location:337 → 531

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:404 → 424

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam00096
Location:346 → 368

zf-C2H2; Zinc finger, C2H2 type

pfam02023
Location:38 → 120

SCAN; SCAN domain

pfam13465
Location:500 → 524

zf-H2C2_2; Zinc-finger double domain