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Lars2 leucyl-tRNA synthetase 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 363172, updated on 26-May-2016
Official Symbol
Lars2provided by RGD
Official Full Name
leucyl-tRNA synthetase 2provided by RGD
Primary source
RGD:1308429
See related
Ensembl:ENSRNOG00000004760
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
Orthologs
Location:
8q32
Exon count:
21
Annotation release Status Assembly Chr Location
105 current Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (132441278..132537176)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 8 NC_005107.3 (131593987..131689876)

Chromosome 8 - NC_005107.4Genomic Context describing neighboring genes Neighboring gene CUB domain containing protein 1 Neighboring gene transmembrane protein 158 Neighboring gene LIM domains containing 1 Neighboring gene SAC1 suppressor of actin mutations 1-like (yeast)

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
aminoacyl-tRNA editing activity IEA
Inferred from Electronic Annotation
more info
 
leucine-tRNA ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
leucine-tRNA ligase activity IEA
Inferred from Electronic Annotation
more info
 
leucine-tRNA ligase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
leucyl-tRNA aminoacylation IBA
Inferred from Biological aspect of Ancestor
more info
 
leucyl-tRNA aminoacylation IEA
Inferred from Electronic Annotation
more info
 
leucyl-tRNA aminoacylation ISO
Inferred from Sequence Orthology
more info
 
regulation of translational fidelity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
NOT cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 
mitochondrion IEA
Inferred from Electronic Annotation
more info
 
mitochondrion ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
probable leucine--tRNA ligase, mitochondrial
Names
leucyl-tRNA synthetase 2, mitochondrial
leucyl-tRNA synthetase, mitochondrial
probable leucyl-tRNA synthetase, mitochondrial
NP_001102257.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108787.1NP_001102257.1  probable leucine--tRNA ligase, mitochondrial

    See identical proteins and their annotated locations for NP_001102257.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473954
    UniProtKB/TrEMBL
    D3Z9N3
    Related
    ENSRNOP00000058878, ENSRNOT00000068233
    Conserved Domains (3) summary
    cd07958
    Location:489614
    Anticodon_Ia_Leu_BEm; Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases
    pfam13603
    Location:114274
    tRNA-synt_1_2; Leucyl-tRNA synthetase, Domain 2
    cl00015
    Location:1489
    nt_trans; nucleotidyl transferase superfamily

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005107.4 Reference Rnor_6.0 Primary Assembly

    Range
    132441278..132537176
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006244201.2XP_006244263.1  

    UniProtKB/TrEMBL
    A0A0G2K9E5
    Related
    ENSRNOP00000074967, ENSRNOT00000087488
    Conserved Domains (4) summary
    cd07958
    Location:677802
    Anticodon_Ia_Leu_BEm; Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases
    cd00812
    Location:82677
    LeuRS_core; catalytic core domain of leucyl-tRNA synthetases
    PRK00390
    Location:56901
    leuS; leucyl-tRNA synthetase; Validated
    pfam13603
    Location:269429
    tRNA-synt_1_2; Leucyl-tRNA synthetase, Domain 2
  2. XM_008766727.1XP_008764949.1  

    Conserved Domains (4) summary
    cd07958
    Location:626751
    Anticodon_Ia_Leu_BEm; Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases
    cd00812
    Location:82626
    LeuRS_core; catalytic core domain of leucyl-tRNA synthetases
    PRK00390
    Location:56850
    leuS; leucyl-tRNA synthetase; Validated
    pfam13603
    Location:218378
    tRNA-synt_1_2; Leucyl-tRNA synthetase, Domain 2

Alternate Rn_Celera

Genomic

  1. AC_000076.1 Alternate Rn_Celera

    Range
    122121425..122216021
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)