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    Syx7 Syntaxin 7 [ Drosophila melanogaster ]

    Gene ID: 36173, updated on 10-May-2012
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    Summary

    Official Symbol
    Syx7provided by Flybase
    Official Full Name
    Syntaxin 7provided by Flybase
    Primary source
    FLYBASE:FBgn0086377
    Locus tag
    Dmel_CG5081
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    avl; Avl; CG5081; Dm Syx7; Dmel\CG5081; DmSyx7; dSyn7; Syx; syx7; SYX7; syx7/avl; Syx7/Avl
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    Genomic context

    Location :
    78D2-78D2
    Sequence :
    Chromosome: 3L; NT_037436.3 (21438922..21441235)
    See Syx7 in Epigenomics, MapViewer

    Chromosome 3L - NT_037436.3Genomic Context describing neighboring genes Neighboring gene CG5664 gene product from transcript CG5664-RA Neighboring gene CG5656 gene product from transcript CG5656-RA Neighboring gene crocodile Neighboring gene CG7204 gene product from transcript CG7204-RA

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. A protein complex network of Drosophila melanogaster. Guruharsha KG, et al. Cell, 2011 Oct 28. PMID 22036573.
    2. Spinster controls Dpp signaling during glial migration in the Drosophila eye. Yuva-Aydemir Y, et al. J Neurosci, 2011 May 11. PMID 21562262.
    3. The full-of-bacteria gene is required for phagosome maturation during immune defense in Drosophila. Akbar MA, et al. J Cell Biol, 2011 Feb 7. PMID 21282466.
    4. A dual function of V0-ATPase a1 provides an endolysosomal degradation mechanism in Drosophila melanogaster photoreceptors. Williamson WR, et al. J Cell Biol, 2010 May 31. PMID 20513768.
    5. Drosophila acinus encodes a novel regulator of endocytic and autophagic trafficking. Haberman AS, et al. Development, 2010 Jul. PMID 20504956.

    See all (44) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:61971 BioGRID:67154 AttD    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:61971 BioGRID:65370 Bet1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:61971 BioGRID:59096 CG12985    BioGRID  PubMed Two-hybrid 
    BioGRID:61971 BioGRID:72605 CG14767    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:61971 BioGRID:62842 CG15098    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:61971 BioGRID:61844 CG1599    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:61971 BioGRID:61186 CG17564    BioGRID  PubMed Two-hybrid 
    BioGRID:61971 BioGRID:65929 CG2023    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:61971 BioGRID:59771 CG2774    BioGRID  PubMed Two-hybrid 
    BioGRID:61971 BioGRID:59432 CG3164    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:61971 BioGRID:64899 CG32138    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:61971 BioGRID:64486 CG3529    BioGRID  PubMed Two-hybrid 
    BioGRID:61971 BioGRID:66392 CG6208    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:61971 BioGRID:65457 CG7668    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:61971 BioGRID:73975 Gos28    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:61971 BioGRID:66662 Past1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:61971 BioGRID:60256 Pvr    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:61971 BioGRID:57598 Sec22    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:61971 BioGRID:59661 Slh    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:61971 BioGRID:65495 Snap    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:61971 BioGRID:66351 Snap24    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:61971 BioGRID:78209 Snap25    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:61971 BioGRID:61901 Syb    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:61971 BioGRID:64830 Syx13    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:61971 BioGRID:59325 Syx16    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:61971 BioGRID:67859 Syx18    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:61971 BioGRID:67788 Syx1A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:61971 BioGRID:57800 Syx4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:61971 BioGRID:60977 Syx5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:61971 BioGRID:65150 Syx8    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:61971 BioGRID:64451 Use1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:61971 BioGRID:58180 Ykt6    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:61971 BioGRID:70919 betaggt-II    BioGRID  PubMed Two-hybrid 
    BioGRID:61971 BioGRID:65132 fax    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:61971 BioGRID:63423 gammaSnap    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:61971 BioGRID:67231 koko    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:61971 BioGRID:64080 membrin    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:61971 BioGRID:63369 usnp    BioGRID  PubMed Affinity Capture-MS 
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    General gene information

    Homology

    • Homologs of the Syx7 gene: The Syx7 gene is conserved in human, chimpanzee, , dog, cow, mouse, rat, chicken, zebrafish, mosquito, S.cerevisiae, K.lactis, , S.pombe, , N.crassa, A.thaliana, and rice.

    Pathways from BioSystems

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    SNAP receptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    SNAP receptor activity NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    endosomal vesicle fusion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    establishment or maintenance of apical/basal cell polarity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    establishment or maintenance of polarity of follicular epithelium IMP
    Inferred from Mutant Phenotype
    more info
    		  
    negative regulation of cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    neurotransmitter secretion NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    positive regulation of endocytosis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    regulation of epithelial cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    		  
    synaptic vesicle docking involved in exocytosis ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    vesicle-mediated transport NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    early endosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    plasma membrane NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
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    General protein information

    Preferred Names
    CG5081 gene product from transcript CG5081-RB
    Names
    CG5081-PA
    CG5081-PB
    Syntaxin7
    Syx7-PA
    Syx7-PB
    avalanche
    dSyntaxin-7
    synatxin7/avalanche
    syntaxin
    syntaxin 7
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.3

      Range
      21438922..21441235
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_168906.1 → NP_730633.1  syntaxin 7, isoform B [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K0X9
      Related
      FBpp0078008, FBtr0078352
      Conserved Domains (2) summary
      cd00179
      Location:22 – 124
      Blast Score: 117
      SynN; Syntaxin N-terminus domain; syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane; they are a family of receptors for intracellular transport vesicles; each target membrane may ...
      cl00152
      Location:195 – 252
      Blast Score: 100
      t_SNARE; Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein (SNAP) REceptor domain; these alpha-helical motifs form twisted and parallel heterotetrameric helix bundles; the core complex contains one helix from a protein that is anchored in ...

    2. NM_168905.1 → NP_730632.1  syntaxin 7, isoform A [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K0X9
      Related
      FBpp0078007, FBtr0078351
      Conserved Domains (2) summary
      cd00179
      Location:22 – 124
      Blast Score: 117
      SynN; Syntaxin N-terminus domain; syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane; they are a family of receptors for intracellular transport vesicles; each target membrane may ...
      cl00152
      Location:195 – 252
      Blast Score: 100
      t_SNARE; Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein (SNAP) REceptor domain; these alpha-helical motifs form twisted and parallel heterotetrameric helix bundles; the core complex contains one helix from a protein that is anchored in ...
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AE014296.4 AAF51726.3
    genomic AE014296.4 AAF51725.1
    mRNA AY069516.1 AAL39661.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VP33.1 GenPept
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    Additional Links

    Gene LinkOut

      Supplemental Content