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    coro [ Drosophila melanogaster ]

    Gene ID: 35596, updated on 9-May-2012
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    Summary

    Official Symbol
    coroprovided by Flybase
    Primary source
    FLYBASE:FBgn0033109
    Locus tag
    Dmel_CG9446
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG9446; Dmel\CG9446
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    Genomic context

    Location :
    42D6-42D6
    Sequence :
    Chromosome: 2R; NT_033778.3 (2749506..2760274, complement)
    See coro in Epigenomics, MapViewer

    Chromosome 2R - NT_033778.3Genomic Context describing neighboring genes Neighboring gene CG15236 gene product from transcript CG15236-RB Neighboring gene mir-4976 stem loop Neighboring gene CG9445 gene product from transcript CG9445-RA Neighboring gene CG9447 gene product from transcript CG9447-RB Neighboring gene Serine protease inhibitor 4

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. A protein complex network of Drosophila melanogaster. Guruharsha KG, et al. Cell, 2011 Oct 28. PMID 22036573.
    2. Systematic genetic analysis of muscle morphogenesis and function in Drosophila. Schnorrer F, et al. Nature, 2010 Mar 11. PMID 20220848.
    3. Identification and analysis of serpin-family genes by homology and synteny across the 12 sequenced Drosophilid genomes. Garrett M, et al. BMC Genomics, 2009 Oct 22. PMID 19849829.
    4. A Drosophila overexpression screen for modifiers of Rho signalling in cytokinesis. Gregory SL, et al. Fly (Austin), 2007 Jan-Feb. PMID 18690061.
    5. Genetic and chemical modifiers of a CUG toxicity model in Drosophila. Garcia-Lopez A, et al. PLoS One, 2008 Feb 13. PMID 18270582.

    See all (17) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. cloning and characterization of coro, which codes for the Drosophila homologue of the F-actin binding protein coronin
      Title: Genetic characterization of the Drosophila homologue of coronin.
    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:61491 BioGRID:57648 CG11448    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:61491 BioGRID:65751 CG14641    BioGRID  PubMed Two-hybrid 
    BioGRID:61491 BioGRID:66987 CG31291    BioGRID  PubMed Two-hybrid 
    BioGRID:61491 BioGRID:58294 CG7766    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:61491 BioGRID:60243 CG8475    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:61491 BioGRID:58975 CG9723    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:61491 BioGRID:69766 Faa    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:61491 BioGRID:59543 Iris    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:61491 BioGRID:67960 Nup358    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:61491 BioGRID:58527 PhKgamma    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:61491 BioGRID:60746 Sir2    BioGRID  PubMed Two-hybrid 
    BioGRID:61491 BioGRID:64396 Zasp66    BioGRID  PubMed Two-hybrid 
    BioGRID:61491 BioGRID:64869 bru-3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:61491 BioGRID:61183 gammaTub37C    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:61491 BioGRID:63817 mRpL23    BioGRID  PubMed Affinity Capture-MS 
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    General gene information

    Homology

    • Homologs of the coro gene: The coro gene is conserved in human, chimpanzee, , dog, cow, mouse, rat, chicken, zebrafish, mosquito, and C.elegans.

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    actin binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    adult somatic muscle development IMP
    Inferred from Mutant Phenotype
    more info
    		  
    Component Evidence Code Pubs
    actin cytoskeleton NAS
    Non-traceable Author Statement
    more info
    		  
    mitotic spindle IDA
    Inferred from Direct Assay
    more info
    		  
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    General protein information

    Preferred Names
    CG9446 gene product from transcript CG9446-RC
    Names
    CG9446-PA
    CG9446-PB
    CG9446-PC
    coro
    coro-PA
    coro-PB
    coro-PC
    coronin
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.3

      Range
      2749506..2760274, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_206031.1 → NP_995753.1  coro, isoform C [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7JVY0
      Related
      FBpp0089194, FBtr0086209
      Conserved Domains (3) summary
      pfam08953
      Location:4 – 68
      Blast Score: 341
      DUF1899; Domain of unknown function (DUF1899)
      pfam08954
      Location:255 – 390
      Blast Score: 579
      DUF1900; Domain of unknown function (DUF1900)
      cl02567
      Location:79 – 295
      Blast Score: 229
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    2. NM_136398.3 → NP_610242.1  coro, isoform A [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7JVY0
      Related
      FBpp0085526, FBtr0086207
      Conserved Domains (3) summary
      pfam08953
      Location:4 – 68
      Blast Score: 341
      DUF1899; Domain of unknown function (DUF1899)
      pfam08954
      Location:255 – 390
      Blast Score: 579
      DUF1900; Domain of unknown function (DUF1900)
      cl02567
      Location:79 – 295
      Blast Score: 229
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    3. NM_165494.1 → NP_724509.1  coro, isoform B [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7JVY0
      Related
      FBpp0085527, FBtr0086208
      Conserved Domains (3) summary
      pfam08953
      Location:4 – 68
      Blast Score: 341
      DUF1899; Domain of unknown function (DUF1899)
      pfam08954
      Location:255 – 390
      Blast Score: 579
      DUF1900; Domain of unknown function (DUF1900)
      cl02567
      Location:79 – 295
      Blast Score: 229
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AE013599.4 AAS64781.1
    mRNA AY118560.1 AAM49929.1
    genomic AE013599.4 AAM70835.1
    genomic AE013599.4 AAF57403.1
    mRNA AF467271.1 AAM74566.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9V993.1 GenPept
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    Additional Links

    Gene LinkOut

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