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    yuri yuri gagarin [ Drosophila melanogaster ]

    Gene ID: 34894, updated on 10-May-2012
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    Summary

    Official Symbol
    yuriprovided by Flybase
    Official Full Name
    yuri gagarinprovided by Flybase
    Primary source
    FLYBASE:FBgn0045842
    Locus tag
    Dmel_CG31732
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BG:DS05639.1; BG:DS07851.11; CG11860; CG12635; CG31732; Dmel\CG31732
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    Genomic context

    Location :
    35C5-35C5
    Sequence :
    Chromosome: 2L; NT_033779.4 (15257267..15264690, complement)
    See yuri in Epigenomics, MapViewer

    Chromosome 2L - NT_033779.4Genomic Context describing neighboring genes Neighboring gene CG3994 gene product from transcript CG3994-RA Neighboring gene down and out Neighboring gene CG3975 gene product from transcript CG3975-RA Neighboring gene lethal (2) 35Cc Neighboring gene Cullin-3 Neighboring gene CG15261 gene product from transcript CG15261-RA

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Tropomyosin is an interaction partner of the Drosophila coiled coil protein yuri gagarin. Texada MJ, et al. Exp Cell Res, 2011 Feb 15. PMID 21126519.
    2. The Drosophila SUN protein Spag4 cooperates with the coiled-coil protein Yuri Gagarin to maintain association of the basal body and spermatid nucleus. Kracklauer MP, et al. J Cell Sci, 2010 Aug 15. PMID 20647369.
    3. A Drosophila behavioral mutant, down and out (dao), is defective in an essential regulator of Erg potassium channels. Fergestad T, et al. Proc Natl Acad Sci U S A, 2010 Mar 23. PMID 20212103.
    4. Yuri gagarin is required for actin, tubulin and basal body functions in Drosophila spermatogenesis. Texada MJ, et al. J Cell Sci, 2008 Jun 1. PMID 18477609.
    5. Sequence finishing and mapping of Drosophila melanogaster heterochromatin. Hoskins RA, et al. Science, 2007 Jun 15. PMID 17569867.

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. study identified Spag4 (previously named Giacomo) as a component of a centriolar-nuclear attachment pathway in spermatogenesis that also requires the coiled-coil protein Yuri and cytoplasmic dynein-dynactin
      Title: The Drosophila SUN protein Spag4 cooperates with the coiled-coil protein Yuri Gagarin to maintain association of the basal body and spermatid nucleus.
    2. Yuri is a component of the motile actin cones that individualize the spermatids and is essential for their formation. Furthermore, Yuri is required for actin accumulation in the dense complex.
      Title: Yuri gagarin is required for actin, tubulin and basal body functions in Drosophila spermatogenesis.
    3. 18 candidate genes are now implicated in the gravitaxic behavior of flies. Yuri, located close to a known locus for gravitaxis, was studied more extensively by transgenic rescue.
      Title: Gravitaxis in Drosophila melanogaster: a forward genetic screen.
    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:60912 BioGRID:66425 CG14684    BioGRID  PubMed Two-hybrid 
    BioGRID:60912 BioGRID:58668 IP3K2    BioGRID  PubMed Two-hybrid 
    BioGRID:60912 BioGRID:65211 Rbp6    BioGRID  PubMed Two-hybrid 
    BioGRID:60912 BioGRID:67078 Ubx    BioGRID  PubMed Two-hybrid 
    BioGRID:60912 BioGRID:64251 lark    BioGRID  PubMed Two-hybrid 
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    General gene information

    Markers

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    gravitaxis NAS
    Non-traceable Author Statement
    more info
    		  
    microtubule basal body organization IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    sperm individualization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    investment cone IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    nuclear envelope IDA
    Inferred from Direct Assay
    more info
    		  
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    General protein information

    Preferred Names
    CG31732 gene product from transcript CG31732-RB
    Names
    CG31732-PB
    CG31732-PC
    CG31732-PD
    CG31732-PF
    CG31732-PH
    CG31732-PI
    CG31732-PJ
    CG31732-PK
    CG31732-PL
    yuri gagarin
    yuri-PB
    yuri-PC
    yuri-PD
    yuri-PF
    yuri-PH
    yuri-PI
    yuri-PJ
    yuri-PK
    yuri-PL
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.4

      Range
      15257267..15264690, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_165106.4 → NP_723903.3  yuri gagarin, isoform B [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9V435
      Related
      FBpp0080269, FBtr0080709
      Conserved Domains (1) summary
      TIGR02169
      Location:359 – 638
      Blast Score: 111
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

    2. NM_001169513.1 → NP_001162984.1  yuri gagarin, isoform J [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JHI6
      Related
      FBpp0290156, FBtr0300934
      Conserved Domains (1) summary
      TIGR02168
      Location:474 – 713
      Blast Score: 106
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    3. NM_001038822.2 → NP_001033911.2  yuri gagarin, isoform L [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q2PDT6
      Related
      FBpp0290157, FBtr0300935
      Conserved Domains (1) summary
      TIGR02168
      Location:639 – 769
      Blast Score: 103
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    4. NM_001038821.1 → NP_001033910.1  yuri gagarin, isoform F [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q2PDT8
      Related
      FBpp0100071, FBtr0100611
      Conserved Domains (1) summary
      TIGR02168
      Location:213 – 411
      Blast Score: 102
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    5. NM_001038820.2 → NP_001033909.2  yuri gagarin, isoform K [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q2PDT7
      Related
      FBpp0290155, FBtr0300933
      Conserved Domains (1) summary
      TIGR02168
      Location:88 – 218
      Blast Score: 99
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    6. NM_165109.2 → NP_723906.1  yuri gagarin, isoform D [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IP47
      Related
      FBpp0080272, FBtr0080712

    7. NM_165107.2 → NP_723904.1  yuri gagarin, isoform C [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VJP8
      Related
      FBpp0080271, FBtr0080711

    8. NM_001038823.2 → NP_001033912.1  yuri gagarin, isoform H [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q2PDT5
      Related
      FBpp0100073, FBtr0100613

    9. NM_001169512.1 → NP_001162983.1  yuri gagarin, isoform I [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K540
      Related
      FBpp0290154, FBtr0300932
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AE014134.5 AAF53449.4
    genomic AE014134.5 ACZ94270.1
    genomic AE014134.5 ABC65905.2
    genomic AE014134.5 ABC65903.1
    genomic AE014134.5 ABC65904.2
    genomic AE014134.5 AAN10894.1
    mRNA BT001564.1 AAN71319.1
    genomic AE014134.5 AAF53447.2
    genomic AE014134.5 ABC65906.1
    mRNA AY051476.1 AAK92900.1
    genomic AE014134.5 ACZ94269.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    AAF53449.2 GenPept
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    Additional Links

    Gene LinkOut

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