Mdh1 Malate dehydrogenase 1 [Drosophila melanogaster] - Gene

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Summary

Official Symbol: Mdh1provided by Flybase
Official Full Name: Malate dehydrogenase 1provided by Flybase
Primary source: FLYBASE:FBgn0262782
Locus tag: Dmel_CG5362
Gene type: protein coding
RNA name: malate dehydrogenase 1
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG5362; cMdh; CT17038; Dmel\CG5362; Mdh; MDH; Mdh-1; MDH-1; Mdh2; MdhD; sMdh

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Genomic context

Location :: 31E1-31F2; 2-37.2 cM

Sequence :: Chromosome: 2L; NT_033779.4 (10393847..10396299, complement)

See Mdh1 in Epigenomics, MapViewer

Chromosome 2L - NT_033779.4 Genomic Context describing neighboring genes

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Genomic regions, transcripts, and products

Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Go to reference sequence details

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Bibliography

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Submit: New GeneRIF Correction

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Interactions

Products	Interactant	Other Gene	Source	Pubs	Description
BioGRID:60498	BioGRID:77525	CG33213	BioGRID	PubMed	Two-hybrid
BioGRID:60498	BioGRID:77797	CG33275	BioGRID	PubMed	Two-hybrid
BioGRID:60498	BioGRID:60811	CG9014	BioGRID	PubMed	Two-hybrid
BioGRID:60498	BioGRID:566815	CR14499	BioGRID	PubMed	Two-hybrid
BioGRID:60498	BioGRID:58272	Lim1	BioGRID	PubMed	Two-hybrid
BioGRID:60498	BioGRID:65996	Zif	BioGRID	PubMed	Two-hybrid
BioGRID:60498	BioGRID:70919	betaggt-II	BioGRID	PubMed	Two-hybrid

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General gene information

Pathways from BioSystems

Citrate cycle (TCA cycle), organism-specific biosystem (from KEGG)
Citrate cycle (TCA cycle), organism-specific biosystemThe citrate cycle (TCA cycle, Krebs cycle) is an important aerobic pathway for the final steps of the oxidation of carbohydrates and fatty acids. The cycle starts with acetyl-CoA, the activated form ...
Citrate cycle (TCA cycle), conserved biosystem (from KEGG)
Citrate cycle (TCA cycle), conserved biosystemThe citrate cycle (TCA cycle, Krebs cycle) is an important aerobic pathway for the final steps of the oxidation of carbohydrates and fatty acids. The cycle starts with acetyl-CoA, the activated form ...
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate, organism-specific biosystem (from KEGG)
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate, organism-specific biosystemPathway module; Carbohydrate and lipid metabolism; Central carbohydrate metabolism
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate, conserved biosystem (from KEGG)
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate, conserved biosystemPathway module; Carbohydrate and lipid metabolism; Central carbohydrate metabolism
Glycolysis and Gluconeogenesis, organism-specific biosystem (from WikiPathways)
Glycolysis and Gluconeogenesis, organism-specific biosystem
Glycolysis and Gluconeogenesis
Glyoxylate and dicarboxylate metabolism, organism-specific biosystem (from KEGG)
Glyoxylate and dicarboxylate metabolism, organism-specific biosystem
Glyoxylate and dicarboxylate metabolism
Glyoxylate and dicarboxylate metabolism, conserved biosystem (from KEGG)
Glyoxylate and dicarboxylate metabolism, conserved biosystem
Glyoxylate and dicarboxylate metabolism
Metabolic pathways, organism-specific biosystem (from KEGG)
Metabolic pathways, organism-specific biosystem
Metabolic pathways
Pyruvate metabolism, organism-specific biosystem (from KEGG)
Pyruvate metabolism, organism-specific biosystem
Pyruvate metabolism
Pyruvate metabolism, conserved biosystem (from KEGG)
Pyruvate metabolism, conserved biosystem
Pyruvate metabolism
TCA Cycle, organism-specific biosystem (from WikiPathways)
TCA Cycle, organism-specific biosystem
TCA Cycle

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General protein information

Preferred Names: CG5362 gene product from transcript CG5362-RA

Names: CG5362-PA; Mdh1-PA; cytoplasmic Mdh; cytosolic malate dehydrogenase; malate dehydrogenase; malate dehydrogenase 1; malic DH

NP_609394.1

EC 1.1.1.37

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NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NT_033779.4

Range

10393847..10396299, complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_135550.1 → NP_609394.1 malate dehydrogenase 1 [Drosophila melanogaster]

Status: REVIEWED

UniProtKB/TrEMBL

Q9VKX2

Related

FBpp0079640, FBtr0080050

Conserved Domains (2) summary

TIGR01758
Location:6 – 328
Blast Score: 1434

MDH_euk_cyt; malate dehydrogenase, NAD-dependent

cd01336
Location:3 – 327
Blast Score: 1547

MDH_cytoplasmic_cytosolic; Cytoplasmic and cytosolic Malate dehydrogenases