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ZSCAN22 zinc finger and SCAN domain containing 22 [ Homo sapiens (human) ]

Gene ID: 342945, updated on 8-May-2016
Official Symbol
ZSCAN22provided by HGNC
Official Full Name
zinc finger and SCAN domain containing 22provided by HGNC
Primary source
HGNC:HGNC:4929
See related
Ensembl:ENSG00000182318 HPRD:01315; MIM:165260; Vega:OTTHUMG00000183463
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HKR2; ZNF50
Orthologs
Location:
19q13.43
Exon count:
6
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 19 NC_000019.10 (58327019..58342349)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (58838385..58853712)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105372481 Neighboring gene uncharacterized LOC105372480 Neighboring gene zinc finger protein 470 pseudogene Neighboring gene microRNA 6806 Neighboring gene alpha-1-B glycoprotein Neighboring gene A1BG antisense RNA 1 Neighboring gene zinc finger protein 446 pseudogene Neighboring gene zinc finger protein 497

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC126679, MGC138482

Gene Ontology Provided by GOA

Function Evidence Code Pubs
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
molecular_function ND
No biological Data available
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
transcription factor activity, sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
biological_process ND
No biological Data available
more info
 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
Preferred Names
zinc finger and SCAN domain-containing protein 22
Names
GLI-Kruppel family member HKR2
krueppel-related zinc finger protein 2
zinc finger protein 50

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001321116.1NP_001308045.1  zinc finger and SCAN domain-containing protein 22 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC010642, AC012313, AK128716
    Conserved Domains (4) summary
    cd07936
    Location:45129
    SCAN; SCAN oligomerization domain
    COG5048
    Location:174482
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:338363
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:326346
    ZF_C2H2; C2H2 Zn finger [structural motif]
  2. NM_001321117.1NP_001308046.1  zinc finger and SCAN domain-containing protein 22 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC010642, AC012313, AK128716, BC143446, DA335630
    Conserved Domains (2) summary
    smart00431
    Location:45153
    SCAN; leucine rich region
    cd07936
    Location:45129
    SCAN; SCAN oligomerization domain
  3. NM_181846.2NP_862829.1  zinc finger and SCAN domain-containing protein 22 isoform 1

    See identical proteins and their annotated locations for NP_862829.1

    Status: VALIDATED

    Source sequence(s)
    AC010642, AC012313, BC112277
    Consensus CDS
    CCDS12975.1
    UniProtKB/Swiss-Prot
    P10073
    Related
    ENSP00000332433, OTTHUMP00000271751, ENST00000329665, OTTHUMT00000466765
    Conserved Domains (4) summary
    cd07936
    Location:45129
    SCAN; SCAN oligomerization domain
    COG5048
    Location:174482
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:338363
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:326346
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p2 Primary Assembly

    Range
    58327019..58342349
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006723190.2XP_006723253.1  

    UniProtKB/Swiss-Prot
    P10073
    Conserved Domains (4) summary
    cd07936
    Location:45129
    SCAN; SCAN oligomerization domain
    COG5048
    Location:174482
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:338363
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:326346
    ZF_C2H2; C2H2 Zn finger [structural motif]
  2. XM_005258865.2XP_005258922.1  

    See identical proteins and their annotated locations for XP_005258922.1

    Conserved Domains (3) summary
    COG5048
    Location:10313
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:174199
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:162182
    ZF_C2H2; C2H2 Zn finger [structural motif]
  3. XM_011526918.1XP_011525220.1  

    See identical proteins and their annotated locations for XP_011525220.1

    Conserved Domains (3) summary
    COG5048
    Location:10313
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:174199
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:162182
    ZF_C2H2; C2H2 Zn finger [structural motif]
  4. XM_006723192.2XP_006723255.1  

    See identical proteins and their annotated locations for XP_006723255.1

    UniProtKB/Swiss-Prot
    P10073
    Conserved Domains (4) summary
    cd07936
    Location:45129
    SCAN; SCAN oligomerization domain
    COG5048
    Location:174482
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:338363
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:326346
    ZF_C2H2; C2H2 Zn finger [structural motif]
  5. XM_006723191.2XP_006723254.1  

    See identical proteins and their annotated locations for XP_006723254.1

    UniProtKB/Swiss-Prot
    P10073
    Conserved Domains (4) summary
    cd07936
    Location:45129
    SCAN; SCAN oligomerization domain
    COG5048
    Location:174482
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:338363
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:326346
    ZF_C2H2; C2H2 Zn finger [structural motif]
  6. XM_011526917.1XP_011525219.1  

    See identical proteins and their annotated locations for XP_011525219.1

    UniProtKB/Swiss-Prot
    P10073
    Conserved Domains (4) summary
    cd07936
    Location:45129
    SCAN; SCAN oligomerization domain
    COG5048
    Location:174482
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:338363
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:326346
    ZF_C2H2; C2H2 Zn finger [structural motif]

Alternate CHM1_1.1

Genomic

  1. NC_018930.2 Alternate CHM1_1.1

    Range
    58832615..58847629
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)