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    GLDN gliomedin [ Homo sapiens (human) ]

    Gene ID: 342035, updated on 26-Feb-2013
    Official Symbol
    GLDNprovided by HGNC
    Official Full Name
    gliomedinprovided by HGNC
    Primary source
    HGNC:29514
    Locus tag
    UNQ9339/PRO34011
    See related
    Ensembl:ENSG00000186417; HPRD:12267; MIM:608603; Vega:OTTHUMG00000131746
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    CLOM; COLM; CRGL2; CRG-L2; UNC-112
    Location :
    15q21.2
    Sequence :
    Chromosome: 15; NC_000015.9 (51633713..51700210)
    See GLDN in Epigenomics, MapViewer

    Chromosome 15 - NC_000015.9Genomic Context describing neighboring genes Neighboring gene cytochrome P450, family 19, subfamily A, polypeptide 1 Neighboring gene uncharacterized LOC100652954 Neighboring gene uncharacterized LOC100996299 Neighboring gene Dmx-like 2 Neighboring gene secretogranin III

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details

    Related articles in PubMed

    1. Nodal proteins are target antigens in Guillain-Barré syndrome. Devaux JJ, et al. J Peripher Nerv Syst, 2012 Mar. PMID 22462667.
    2. Fibronectin type III-like domains of neurofascin-186 protein mediate gliomedin binding and its clustering at the developing nodes of Ranvier. Labasque M, et al. J Biol Chem, 2011 Dec 9. PMID 22009740.
    3. Gliomedin mediates Schwann cell-axon interaction and the molecular assembly of the nodes of Ranvier. Eshed Y, et al. Neuron, 2005 Jul 21. PMID 16039564.
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039.
    5. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. Clark HF, et al. Genome Res, 2003 Oct. PMID 12975309.

    See all (7) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. gliomedin, NF186, and contactin are novel target antigens in Guillain-Barre syndrome
      Title: Nodal proteins are target antigens in Guillain-Barré syndrome.
    2. Fibronectin type III-like domains of neurofascin-186 protein mediate gliomedin binding and its clustering at the developing nodes of Ranvier
      Title: Fibronectin type III-like domains of neurofascin-186 protein mediate gliomedin binding and its clustering at the developing nodes of Ranvier.
    Submit: New GeneRIF Correction

    Review eQTL and phenotype association data in this region using PheGenI

    Markers

    Genotypes

    Homology

    Clone Names

    • FLJ23917

    Gene Ontology Provided by GOA

    Process Evidence Code Pubs
    cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    nervous system development IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    collagen IEA
    Inferred from Electronic Annotation
    more info
    		  
    extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		  
    integral to membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    Preferred Names
    gliomedin
    Names
    gliomedin
    collomin
    colmedin

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_181789.2 → NP_861454.2  gliomedin

      Status: VALIDATED

      Source sequence(s)
      AC020891, BK001262
      Consensus CDS
      CCDS10140.2
      UniProtKB/Swiss-Prot
      Q6ZMI3
      Related
      ENSP00000335196, OTTHUMP00000162541, ENST00000335449, OTTHUMT00000254667
      Conserved Domains (2) summary
      pfam02191
      Location:303 – 544
      Blast Score: 766
      OLF; Olfactomedin-like domain
      pfam01391
      Location:173 – 220
      Blast Score: 129
      Collagen; Collagen triple helix repeat (20 copies)

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 104

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh37.p10 Primary Assembly

    Genomic

    1. NC_000015.9 Reference GRCh37.p10 Primary Assembly

      Range
      51633713..51700210
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate HuRef

    Genomic

    1. AC_000147.1 Alternate HuRef

      Range
      28463790..28530158
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate CHM1_1.0

    Genomic

    1. NC_018926.1 Alternate CHM1_1.0

      Range
      31700311..31766814
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    genomic ABBA01039083.1 (989..10793) None
    genomic ABBA01039084.1 None
    genomic ABBA01039085.1 None
    genomic AC020891.8 (71205..137704) None
    genomic AMYH01006642.1 (115487..181990) None
    genomic CH471082.1 EAW77418.1
      EAW77419.1
    mRNA AK023623.1 None
    mRNA AK095128.1 None
    mRNA AK172756.1 BAD18742.1
    mRNA AK308933.1 None
    mRNA AK310755.1 None
    mRNA AY358144.1 AAQ88511.1
    mRNA BC113397.1 AAI13398.1
    mRNA BC113399.1 AAI13400.1
    mRNA BK001262.1 DAA01143.1
    mRNA BX538105.1 CAD98018.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6ZMI3.1 GenPept UniProtKB/Swiss-Prot:Q6ZMI3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Medical
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous

      Supplemental Content

      Table of contents

      Related information

      • Order cDNA clone
        Order cDNA clone
      • BioAssay
        Related PubChem BioAssays
      • BioProjects
        BioProjects related to a gene
      • CCDS
        Links from Gene to CCDS are established if a gene encodes a protein sequence that is a member of a Consensus CDS (CCDS).
      • Conserved Domains
        Conserved Domain Database Links between Entrez Gene and Conserved Domain Database (CDD) are calculated from the domains annotated by the CDD group on Reference Sequence proteins.
      • dbVar
        Link from Gene to dbVar
      • Full text in PMC
        PMC links
      • Full text in PMC_nucleotide
        Full text in PubMedCentral identified from shared sequence links
      • GAP
        GAP Links
      • Genome
        Genome records having the gene annotated on corresponding genomic reference sequence.
      • GEO Profiles
        Related GEO
      • HomoloGene
        Links between HomoloGene and Gene are provided by the HomoloGene group when a gene is included in a HomoloGene record.
      • Map Viewer
        These links are maintained by the Map Viewer group and are provided when a GeneID is annotated on a map for the same species.
      • Nucleotide
        Link to related Nucleotide entry
      • OMIM
        Links between OMIM and Gene are calculated by Gene based on MIM numbers included in the summary and phenotype sections of the Gene record.
      • Probe
        Related Probe entry
      • Protein
        Link to related protein entry
      • PubChem Compound
        PubChem Compounds
      • PubChem Substance
        PubChem Substances
      • PubMed
        Links between Gene and PubMed are the result of the following: 1. Manual curation within NCBI. Part of the process of generating a REVIEWED RefSeq is an analysis of the current literature. Papers that are seminal in defining the gene, its sequence, and its function are added to the record at that time. Alert users point out gaps or errors in papers associated with a Gene record. These messages are reviewed and implemented as required. 2. Integration of information from other public databases. Gene integrates gene-citation from resources external to NCBI such as model organism-specific databases, Gene Ontology (GO), groups curating interactions, and sequence databases. The assumption in using these source is that they report citations specific to a gene in a known species. Gene does not process citations from OMIM automatically, because many of citations in OMIM refer to studies of genes in species other than human.
      • PubMed (GeneRIF)
        GeneRIF -- Gene Reference Into Function Staff of the Index Section in the National Library of Medicine review the current literature. When they find articles focused on the structure and function of a gene, they write a brief summary of the impact of the paper and make the connection between the citation (PubMed) and Gene. An interface exists for interested users to submit such data as well. http://www.ncbi.nlm.nih.gov/projects/GeneRIF/GeneRIFhelp.html
      • PubMed (OMIM)
        Links are provided when Gene has a link to a record in OMIM, and OMIM explicitly cites these publications in PubMed.
      • PubMed(nucleotide/PMC)
        Citations in PubMed identified from shared sequence and PMC links.
      • RefSeq Proteins
        Link to Protein RefSeqs
      • RefSeq RNAs
        Link to Nucleotide RefSeq RNAs
      • SNP
        Related SNP records
      • SNP: GeneView
        SNPs linked from GeneView
      • SNP: Genotype
        Gene Genotype Report
      • Taxonomy
        Link to related taxonomy entry
      • UniGene
        Links are provided between Gene and UniGene when both databases calculate links to the same mRNA record (gi).
      • UniSTS
        Related UniSTS records

      Links to other resources

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