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    NEK5 NIMA (never in mitosis gene a)-related kinase 5 [ Homo sapiens ]

    Gene ID: 341676, updated on 11-May-2012
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    Summary

    Official Symbol
    NEK5provided by HGNC
    Official Full Name
    NIMA (never in mitosis gene a)-related kinase 5provided by HGNC
    Primary source
    HGNC:7748
    See related
    Ensembl:ENSG00000197168; Vega:OTTHUMG00000016957
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    MGC75495
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    Genomic context

    Location :
    13q14.3
    Sequence :
    Chromosome: 13; NC_000013.10 (52638898..52703214, complement)
    See NEK5 in Epigenomics, MapViewer

    Chromosome 13 - NC_000013.10Genomic Context describing neighboring genes Neighboring gene asparagine-linked glycosylation 11, alpha-1,2-mannosyltransferase homolog (yeast) Neighboring gene serine/threonine-protein kinase Nek5-like Neighboring gene UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast) Neighboring gene NIMA (never in mitosis gene a)-related kinase 3 Neighboring gene thrombospondin, type I, domain containing 1 pseudogene 1

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.
    2. The DNA sequence and analysis of human chromosome 13. Dunham A, et al. Nature, 2004 Apr 1. PMID 15057823.
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.
    4. The NIMA kinase: a mitotic regulator in Aspergillus nidulans and vertebrate cells. Lu KP, et al. Prog Cell Cycle Res, 1995. PMID 9552363.

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
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    Phenotypes

    Review eQTL and phenotype association data in this region using PheGenI

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    General gene information

    Markers

    Genotypes

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
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    General protein information

    Preferred Names
    serine/threonine-protein kinase Nek5
    Names
    serine/threonine-protein kinase Nek5
    nimA-related protein kinase 5
    never in mitosis A-related kinase 5
    NP_954983.1
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    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199289.1 → NP_954983.1  serine/threonine-protein kinase Nek5

      Status: PROVISIONAL

      Source sequence(s)
      BC063885
      Consensus CDS
      CCDS31979.1
      UniProtKB/Swiss-Prot
      Q6P3R8
      Related
      ENSP00000347767, OTTHUMP00000018442, ENST00000355568, OTTHUMT00000045045
      Conserved Domains (2) summary
      cd08225
      Location:3 – 259
      Blast Score: 1381
      STKc_Nek5; Catalytic domain of the Protein Serine/Threonine Kinase, Never In Mitosis gene A-related kinase 5
      smart00220
      Location:4 – 259
      Blast Score: 758
      S_TKc; Serine/Threonine protein kinases, catalytic domain

    RefSeqs of Annotated Genomes: Build 37.3

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh37.p5 Primary Assembly

    Genomic

    1. NC_000013.10 Reference GRCh37.p5 Primary Assembly

      Range
      52638898..52703214, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate HuRef

    Genomic

    1. AC_000145.1 Alternate HuRef

      Range
      33427163..33491350, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AL139082.18 CAI12892.2
    mRNA AK126330.1 None
    mRNA BC063885.1 AAH63885.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6P3R8.1 GenPept UniProtKB/Swiss-Prot:Q6P3R8
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    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous

      Supplemental Content

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