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H1FNT H1 histone family member N, testis specific [ Homo sapiens (human) ]

Gene ID: 341567, updated on 26-May-2016
Official Symbol
H1FNTprovided by HGNC
Official Full Name
H1 histone family member N, testis specificprovided by HGNC
Primary source
HGNC:HGNC:24893
See related
Ensembl:ENSG00000187166 HPRD:17084; Vega:OTTHUMG00000169904
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
H1.7; H1T2
Summary
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-independent histone that is a member of the histone H1 family. The related mouse gene encodes a testis specific protein that is required for spermatogenesis and male fertility. [provided by RefSeq, Oct 2015]
Orthologs
Location:
12q13.11
Exon count:
1
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 12 NC_000012.12 (48328980..48330279)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (48722763..48724062)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102725258 Neighboring gene olfactory receptor family 10 subfamily AD member 1 Neighboring gene uncharacterized LOC105369753 Neighboring gene zinc finger protein 641 Neighboring gene olfactory receptor family 5 subfamily BK member 1 pseudogene

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
DNA binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
chromosome condensation IEA
Inferred from Electronic Annotation
more info
 
multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
sperm chromatin condensation ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
spermatid nucleus elongation ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Component Evidence Code Pubs
nuclear chromatin ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
testis-specific H1 histone
Names
H1 histone family, member N, testis-specific
HANP1
haploid germ cell-specific nuclear protein 1
histone H1t2
testis secretory sperm-binding protein Li 223n

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_181788.1NP_861453.1  testis-specific H1 histone

    See identical proteins and their annotated locations for NP_861453.1

    Status: REVIEWED

    Source sequence(s)
    AY302593
    Consensus CDS
    CCDS8762.1
    UniProtKB/Swiss-Prot
    Q75WM6
    Related
    ENSP00000334805, OTTHUMP00000242443, ENST00000335017, OTTHUMT00000406516

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p2 Primary Assembly

    Range
    48328980..48330279
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018923.2 Alternate CHM1_1.1

    Range
    48688136..48689435
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)