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    Cka Connector of kinase to AP-1 [ Drosophila melanogaster ]

    Gene ID: 34096, updated on 10-May-2012
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    Summary

    Official Symbol
    Ckaprovided by Flybase
    Official Full Name
    Connector of kinase to AP-1provided by Flybase
    Primary source
    FLYBASE:FBgn0044323
    Locus tag
    Dmel_CG7392
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    5836; anon-WO0172774.174; anon-WO0172774.175; anon-WO0172774.177; anon-WO0172774.179; CG7392; cka; CKA; Dcka; Dmel\CG7392; l(2)05836; l(2)s1883
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    Genomic context

    Location :
    28D3-28D3
    Sequence :
    Chromosome: 2L; NT_033779.4 (8030722..8039598)
    See Cka in Epigenomics, MapViewer

    Chromosome 2L - NT_033779.4Genomic Context describing neighboring genes Neighboring gene Transglutaminase Neighboring gene CG7367 gene product from transcript CG7367-RB Neighboring gene barrier to autointegration factor Neighboring gene ncRNA Neighboring gene CG7429 gene product from transcript CG7429-RA Neighboring gene Ribosomal protein L36A

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Mapping of signaling networks through synthetic genetic interaction analysis by RNAi. Horn T, et al. Nat Methods, 2011 Apr. PMID 21378980.
    2. Combined functional genomic and proteomic approaches identify a PP2A complex as a negative regulator of Hippo signaling. Ribeiro PS, et al. Mol Cell, 2010 Aug 27. PMID 20797625.
    3. A genomewide RNA interference screen for modifiers of aggregates formation by mutant Huntingtin in Drosophila. Zhang S, et al. Genetics, 2010 Apr. PMID 20100940.
    4. Comparative analysis of argonaute-dependent small RNA pathways in Drosophila. Zhou R, et al. Mol Cell, 2008 Nov 21. PMID 19026789.
    5. Vector and parameters for targeted transgenic RNA interference in Drosophila melanogaster. Ni JQ, et al. Nat Methods, 2008 Jan. PMID 18084299.

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:60230 BioGRID:64126 CG10483    BioGRID  PubMed Two-hybrid 
    BioGRID:60230 BioGRID:63867 CG11486    BioGRID  PubMed Two-hybrid 
    BioGRID:60230 BioGRID:65746 CG12581    BioGRID  PubMed Two-hybrid 
    BioGRID:60230 BioGRID:61438 CG7856    BioGRID  PubMed Two-hybrid 
    BioGRID:60230 BioGRID:60254 CG8292    BioGRID  PubMed Two-hybrid 
    BioGRID:60230 BioGRID:302275 CSN8    BioGRID  PubMed Two-hybrid 
    BioGRID:60230 BioGRID:65193 Cpr73D    BioGRID  PubMed Two-hybrid 
    BioGRID:60230 BioGRID:67007 Mhcl    BioGRID  PubMed Two-hybrid 
    BioGRID:60230 BioGRID:62759 Nup75    BioGRID  PubMed Two-hybrid 
    BioGRID:60230 BioGRID:77789 Pp2A-29B    BioGRID  PubMed Two-hybrid 
    BioGRID:60230 BioGRID:65820 opa    BioGRID  PubMed Two-hybrid 
    BioGRID:60230 BioGRID:65697 srpk79D    BioGRID  PubMed Two-hybrid 
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    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    JNK cascade NAS
    Non-traceable Author Statement
    more info
    		  
    JNK cascade TAS
    Traceable Author Statement
    more info
    		 PubMed 
    compound eye photoreceptor development IMP
    Inferred from Mutant Phenotype
    more info
    		  
    dorsal closure IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    dorsal closure NAS
    Non-traceable Author Statement
    more info
    		  
    dorsal closure TAS
    Traceable Author Statement
    more info
    		 PubMed 
    phagocytosis, engulfment IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    positive regulation of JNK cascade IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    positive regulation of JNK cascade IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    mitotic spindle IDA
    Inferred from Direct Assay
    more info
    		  
    nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
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    General protein information

    Preferred Names
    CG7392 gene product from transcript CG7392-RB
    Names
    CG7392-PA
    CG7392-PB
    CG7392-PC
    CG7392-PD
    CG7392-PE
    CG7392-PF
    Cka-PA
    Cka-PB
    Cka-PC
    Cka-PD
    Cka-PE
    Cka-PF
    WD-40-family-member
    connector of kinase to AP-1
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.4

      Range
      8030722..8039598
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_164779.2 → NP_723334.1  connector of kinase to AP-1, isoform B [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VLT9
      Related
      FBpp0079159
      Conserved Domains (2) summary
      cd00200
      Location:410 – 729
      Blast Score: 464
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      pfam08232
      Location:98 – 236
      Blast Score: 481
      Striatin; Striatin family

    2. NM_001259007.1 → NP_001245936.1  connector of kinase to AP-1, isoform E [Drosophila melanogaster]

      Status: REVIEWED

    3. NM_001259008.1 → NP_001245937.1  connector of kinase to AP-1, isoform F [Drosophila melanogaster]

      Status: REVIEWED

    4. NM_135333.3 → NP_609177.1  connector of kinase to AP-1, isoform A [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VLT9
      Related
      FBpp0079158
      Conserved Domains (2) summary
      cd00200
      Location:410 – 729
      Blast Score: 464
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      pfam08232
      Location:98 – 236
      Blast Score: 481
      Striatin; Striatin family

    5. NM_164781.2 → NP_723336.1  connector of kinase to AP-1, isoform D [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VLT9
      Related
      FBpp0079160
      Conserved Domains (2) summary
      cd00200
      Location:410 – 729
      Blast Score: 464
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      pfam08232
      Location:98 – 236
      Blast Score: 481
      Striatin; Striatin family

    6. NM_164780.2 → NP_723335.1  connector of kinase to AP-1, isoform C [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VLT9
      Related
      FBpp0079161
      Conserved Domains (2) summary
      cd00200
      Location:410 – 729
      Blast Score: 464
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      pfam08232
      Location:98 – 236
      Blast Score: 481
      Striatin; Striatin family
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AE014134.5 AAN10652.1
    genomic AE014134.5 AAN10651.1
    genomic AE014134.5 AAF52594.2
    mRNA AF364305.1 AAK48946.1
    genomic AE014134.5 AAF52593.2
    mRNA AY061460.1 AAL29008.1
    genomic AE014134.5 AFH03610.1
    genomic AE014134.5 AFH03611.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VLT9.1 GenPept
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    Additional Links

    Gene LinkOut

      Supplemental Content