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    homer [ Drosophila melanogaster ]

    Gene ID: 33944, updated on 9-May-2012
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    Summary

    Official Symbol
    homerprovided by Flybase
    Primary source
    FLYBASE:FBgn0025777
    Locus tag
    Dmel_CG11324
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BEST:LD03829; CG11324; dhom; Dhom; Dhomer; Dm Homer; Dmel\CG11324; Dvh; Hom; Homer; LD03829
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    Genomic context

    Location :
    27A1-27A1
    Sequence :
    Chromosome: 2L; NT_033779.4 (6720395..6723355, complement)
    See homer in Epigenomics, MapViewer

    Chromosome 2L - NT_033779.4Genomic Context describing neighboring genes Neighboring gene Gonadotropin-releasing hormone receptor Neighboring gene CG11188 gene product from transcript CG11188-RA Neighboring gene CG11199 gene product from transcript CG11199-RB Neighboring gene Tubulin tyrosine ligase-like 3B

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Age, but not experience, affects courtship gene expression in male Drosophila melanogaster. Ruedi EA, et al. PLoS One, 2009 Jul 7. PMID 19582156.
    2. Context-specific requirements of functional domains of the Spectraplakin Short stop in vivo. Bottenberg W, et al. Mech Dev, 2009 Jul. PMID 19409984.
    3. Dynein-dynactin complex is essential for dendritic restriction of TM1-containing Drosophila Dscam. Yang JS, et al. PLoS One, 2008. PMID 18946501.
    4. Sequence finishing and mapping of Drosophila melanogaster heterochromatin. Hoskins RA, et al. Science, 2007 Jun 15. PMID 17569867.
    5. The Release 5.1 annotation of Drosophila melanogaster heterochromatin. Smith CD, et al. Science, 2007 Jun 15. PMID 17569856.

    See all (28) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. null homer mutant flies exhibit both increased sensitivity to the sedative effects of ethanol and failure to develop normal levels of rapid tolerance
      Title: Drosophila homer is required in a small set of neurons including the ellipsoid body for normal ethanol sensitivity and tolerance.
    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:60097 BioGRID:71866 Atpalpha    BioGRID  PubMed Two-hybrid 
    BioGRID:60097 BioGRID:68597 CG11576    BioGRID  PubMed Two-hybrid 
    BioGRID:60097 BioGRID:62058 CG13189    BioGRID  PubMed Two-hybrid 
    BioGRID:60097 BioGRID:62972 CG13428    BioGRID  PubMed Two-hybrid 
    BioGRID:60097 BioGRID:67765 CG13599    BioGRID  PubMed Two-hybrid 
    BioGRID:60097 BioGRID:63950 CG14982    BioGRID  PubMed Two-hybrid 
    BioGRID:60097 BioGRID:58436 CG1637    BioGRID  PubMed Two-hybrid 
    BioGRID:60097 BioGRID:61132 CG17322    BioGRID  PubMed Two-hybrid 
    BioGRID:60097 BioGRID:65916 CG2091    BioGRID  PubMed Two-hybrid 
    BioGRID:60097 BioGRID:66987 CG31291    BioGRID  PubMed Two-hybrid 
    BioGRID:60097 BioGRID:65869 CG31550    BioGRID  PubMed Two-hybrid 
    BioGRID:60097 BioGRID:63518 CG3683    BioGRID  PubMed Two-hybrid 
    BioGRID:60097 BioGRID:60907 CG4168    BioGRID  PubMed Two-hybrid 
    BioGRID:60097 BioGRID:63186 CG4554    BioGRID  PubMed Two-hybrid 
    BioGRID:60097 BioGRID:62563 CG4945    BioGRID  PubMed Two-hybrid 
    BioGRID:60097 BioGRID:62290 CG6543    BioGRID  PubMed Two-hybrid 
    BioGRID:60097 BioGRID:65639 CG7172    BioGRID  PubMed Two-hybrid 
    BioGRID:60097 BioGRID:61730 CG8235    BioGRID  PubMed Two-hybrid 
    BioGRID:60097 BioGRID:62133 CG8834    BioGRID  PubMed Two-hybrid 
    BioGRID:60097 BioGRID:61309 CG9331    BioGRID  PubMed Two-hybrid 
    BioGRID:60097 BioGRID:68770 COQ7    BioGRID  PubMed Two-hybrid 
    BioGRID:60097 BioGRID:61989 Cpr47Ee    BioGRID  PubMed Two-hybrid 
    BioGRID:60097 BioGRID:67413 Elongin-B    BioGRID  PubMed Two-hybrid 
    BioGRID:60097 BioGRID:67397 Ir92a    BioGRID  PubMed Two-hybrid 
    BioGRID:60097 BioGRID:59580 Or22b    BioGRID  PubMed Two-hybrid 
    BioGRID:60097 BioGRID:62684 RhoGAP54D    BioGRID  PubMed Two-hybrid 
    BioGRID:60097 BioGRID:62034 Roc2    BioGRID  PubMed Two-hybrid 
    BioGRID:60097 BioGRID:65863 RpL35A    BioGRID  PubMed Two-hybrid 
    BioGRID:60097 BioGRID:77830 Trl    BioGRID  PubMed Two-hybrid 
    BioGRID:60097 BioGRID:63751 drpr    BioGRID  PubMed Two-hybrid 
    BioGRID:60097 BioGRID:64769 eyg    BioGRID  PubMed Two-hybrid 
    BioGRID:60097 BioGRID:57763 gt    BioGRID  PubMed Two-hybrid 
    BioGRID:60097 BioGRID:66754 omd    BioGRID  PubMed Two-hybrid 
    BioGRID:60097 BioGRID:66490 scpr-B    BioGRID  PubMed Two-hybrid 
    BioGRID:60097 BioGRID:66482 scpr-C    BioGRID  PubMed Two-hybrid 
    BioGRID:60097 BioGRID:62797 slim    BioGRID  PubMed Two-hybrid 
    BioGRID:60097 BioGRID:68086 tx    BioGRID  PubMed Two-hybrid 
    BioGRID:60097 BioGRID:63809 yellow-g    BioGRID  PubMed Two-hybrid 
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    General gene information

    Homology

    • Homologs of the homer gene: The homer gene is conserved in human, chimpanzee, , dog, cow, mouse, rat, chicken, zebrafish, and mosquito.

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    adult behavior IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    behavioral response to ethanol IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    regulation of locomotion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    response to ethanol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    dendrite IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
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    General protein information

    Preferred Names
    CG11324 gene product from transcript CG11324-RC
    Names
    CG11324-PA
    CG11324-PB
    CG11324-PC
    d-Homer
    drosophila Ves-1 homolog
    homer
    homer-PA
    homer-PB
    homer-PC
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.4

      Range
      6720395..6723355, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001042876.1 → NP_001036341.1  homer, isoform C [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E8S7
      Related
      FBpp0110075, FBtr0110778
      Conserved Domains (1) summary
      cd01206
      Location:1 – 111
      Blast Score: 542
      Homer; Homer type EVH1 domain

    2. NM_058048.3 → NP_477396.1  homer, isoform A [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      O96607
      Related
      FBpp0078936, FBtr0079306
      Conserved Domains (1) summary
      cd01206
      Location:1 – 111
      Blast Score: 544
      Homer; Homer type EVH1 domain

    3. NM_164706.1 → NP_723207.1  homer, isoform B [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VM94
      Related
      FBpp0078937, FBtr0079307
      Conserved Domains (1) summary
      cd01206
      Location:6 – 114
      Blast Score: 532
      Homer; Homer type EVH1 domain
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AE014134.5 ABI31295.1
    mRNA BT004910.1 AAO49163.1
    mRNA AF093266.1 AAC71030.1
    genomic AE014134.5 AAF52428.1
    genomic AE014134.5 AAF52429.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    O96607.1 GenPept
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    Additional Links

    Gene LinkOut

      Supplemental Content