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TAS2R60 taste 2 receptor member 60 [ Homo sapiens (human) ]

Gene ID: 338398, updated on 7-May-2016
Official Symbol
TAS2R60provided by HGNC
Official Full Name
taste 2 receptor member 60provided by HGNC
Primary source
HGNC:HGNC:20639
See related
Ensembl:ENSG00000185899 HPRD:18159; MIM:613968; Vega:OTTHUMG00000154891
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
T2R56; T2R60
Orthologs
Location:
7q35
Exon count:
1
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 7 NC_000007.14 (143443453..143444409)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (143140546..143141502)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene zyxin Neighboring gene EPH receptor A1 Neighboring gene EPHA1 antisense RNA 1 Neighboring gene taste 2 receptor member 62 pseudogene Neighboring gene taste 2 receptor member 41 Neighboring gene olfactory receptor family 2 subfamily R member 1 pseudogene

  • Class C/3 (Metabotropic glutamate/pheromone receptors), organism-specific biosystem (from REACTOME)
    Class C/3 (Metabotropic glutamate/pheromone receptors), organism-specific biosystemThe class C G-protein-coupled receptors are a class of G-protein coupled receptors that include the metabotropic glutamate receptors and several additional receptors (Brauner-Osborne H et al, 2007). ...
  • G alpha (i) signalling events, organism-specific biosystem (from REACTOME)
    G alpha (i) signalling events, organism-specific biosystemThe classical signalling mechanism for G alpha (i) is inhibition of the cAMP dependent pathway through inhibition of adenylate cyclase. Decreased production of cAMP from ATP results in decreased act...
  • GPCR downstream signaling, organism-specific biosystem (from REACTOME)
    GPCR downstream signaling, organism-specific biosystemG protein-coupled receptors (GPCRs) are classically defined as the receptor, G-protein and downstream effectors, the alpha subunit of the G-protein being the primary signaling molecule. However, it h...
  • GPCR ligand binding, organism-specific biosystem (from REACTOME)
    GPCR ligand binding, organism-specific biosystemThere are more than 800 G-protein coupled receptor (GPCRs) in the human genome, making it the largest receptor superfamily. GPCRs are also the largest class of drug targets, involved in virtually all...
  • Signal Transduction, organism-specific biosystem (from REACTOME)
    Signal Transduction, organism-specific biosystemSignal transduction is a process in which extracellular signals elicit changes in cell state and activity. Transmembrane receptors sense changes in the cellular environment by binding ligands, such a...
  • Signaling by GPCR, organism-specific biosystem (from REACTOME)
    Signaling by GPCR, organism-specific biosystemG protein-coupled receptors (GPCRs; 7TM receptors; seven transmembrane domain receptors; heptahelical receptors; G protein-linked receptors [GPLR]) are the largest family of transmembrane receptors i...
  • Taste transduction, organism-specific biosystem (from KEGG)
    Taste transduction, organism-specific biosystemFive basic tastes are recognized by humans and most other animals - bitter, sweet, sour, salty and umami. In vertebrates, taste stimuli are detected by taste receptor cells (TRCs). At least three dis...
  • Taste transduction, conserved biosystem (from KEGG)
    Taste transduction, conserved biosystemFive basic tastes are recognized by humans and most other animals - bitter, sweet, sour, salty and umami. In vertebrates, taste stimuli are detected by taste receptor cells (TRCs). At least three dis...

Markers

Homology

Clone Names

  • MGC119154, MGC119155

Gene Ontology Provided by GOA

Function Evidence Code Pubs
G-protein coupled receptor activity NAS
Non-traceable Author Statement
more info
PubMed 
NOT bitter taste receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
integral component of membrane IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane TAS
Traceable Author Statement
more info
 
Preferred Names
taste receptor type 2 member 60
Names
taste receptor type 2 member 56
taste receptor, type 2, member 60

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177437.1NP_803186.1  taste receptor type 2 member 60

    See identical proteins and their annotated locations for NP_803186.1

    Status: PROVISIONAL

    Source sequence(s)
    AY114094
    Consensus CDS
    CCDS5885.1
    UniProtKB/Swiss-Prot
    P59551
    Related
    ENSP00000327724, OTTHUMP00000206897, ENST00000332690, OTTHUMT00000337541
    Conserved Domains (1) summary
    pfam05296
    Location:32304
    TAS2R; Mammalian taste receptor protein (TAS2R)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p2 Primary Assembly

    Range
    143443453..143444409
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018918.2 Alternate CHM1_1.1

    Range
    143077470..143078423
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)