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    Spindly [ Drosophila melanogaster ]

    Gene ID: 33578, updated on 26-Jan-2012
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    Summary

    Official Symbol
    Spindlyprovided by Flybase
    Primary source
    FLYBASE:FBgn0031549
    Locus tag
    Dmel_CG15415
    Gene type
    protein coding
    RNA name
    spindly
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG15415; Dmel\CG15415
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    Genomic context

    Location :
    24A1-24A1
    Sequence :
    Chromosome: 2L; NT_033779.4 (3527387..3530317, complement)
    See Spindly in Epigenomics, MapViewer

    Chromosome 2L - NT_033779.4Genomic Context describing neighboring genes Neighboring gene CG8851 gene product from transcript CG8851-RA Neighboring gene Scavenger receptor class C, type IV Neighboring gene CG8852 gene product from transcript CG8852-RA Neighboring gene CG8853 gene product from transcript CG8853-RA Neighboring gene drumstick

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Spindly, a novel protein essential for silencing the spindle assembly checkpoint, recruits dynein to the kinetochore. Griffis ER, et al. J Cell Biol, 2007 Jun 18. PMID 17576797.
    2. Sequence finishing and mapping of Drosophila melanogaster heterochromatin. Hoskins RA, et al. Science, 2007 Jun 15. PMID 17569867.
    3. The Release 5.1 annotation of Drosophila melanogaster heterochromatin. Smith CD, et al. Science, 2007 Jun 15. PMID 17569856.
    4. Towards a comprehensive analysis of the protein phosphatase 1 interactome in Drosophila. Bennett D, et al. J Mol Biol, 2006 Nov 24. PMID 17007873.
    5. Combined evidence annotation of transposable elements in genome sequences. Quesneville H, et al. PLoS Comput Biol, 2005 Jul. PMID 16110336.

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. Spindly is a novel regulator of mitotic dynein, functioning specifically to target dynein to kinetochores.
      Title: Spindly, a novel protein essential for silencing the spindle assembly checkpoint, recruits dynein to the kinetochore.
    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:59788 BioGRID:72126 Pp1-87B    BioGRID  PubMed Two-hybrid 
    BioGRID:59788 BioGRID:66481 RpL3    BioGRID  PubMed Two-hybrid 
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    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    protein phosphatase 1 binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    regulation of mitotic metaphase/anaphase transition IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    kinetochore IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    microtubule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
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    General protein information

    Preferred Names
    CG15415 gene product from transcript CG15415-RB
    Names
    CG15415-PB
    Spindly-PB
    spindly
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.4

      Range
      3527387..3530317, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_134947.2 → NP_608791.2  spindly [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VQS4
      Related
      FBpp0290805, FBtr0301590
      Conserved Domains (1) summary
      COG1196
      Location:30 – 356
      Blast Score: 142
      Smc; Chromosome segregation ATPases [Cell division and chromosome partitioning]
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AE014134.5 AAF51090.2
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    Additional Links

    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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