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ndc1 NDC1 transmembrane nucleoporin [ Danio rerio (zebrafish) ]

Gene ID: 335236, updated on 27-Mar-2024

Summary

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Official Symbol
ndc1provided by ZNC
Official Full Name
NDC1 transmembrane nucleoporinprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-7176
See related
Ensembl:ENSDARG00000021120 AllianceGenome:ZFIN:ZDB-GENE-030131-7176
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
tmem48; zgc:55636; wu:fk93f04
Summary
Predicted to enable protein-macromolecule adaptor activity. Predicted to be involved in nuclear pore organization. Predicted to act upstream of or within mRNA transport and protein transport. Predicted to be located in nuclear membrane. Predicted to be integral component of membrane. Predicted to be part of nuclear pore transmembrane ring. Orthologous to human NDC1 (NDC1 transmembrane nucleoporin). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
18
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (26576832..26590623, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (26921201..26935097, complement)

Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene si:ch211-106k21.5 Neighboring gene zinc finger protein GLIS1-like Neighboring gene uncharacterized LOC101883238 Neighboring gene zgc:113691 Neighboring gene Yip1 domain family, member 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Ezh2 promotes clock function and hematopoiesis independent of histone methyltransferase activity in zebrafish. Zhong Y, et al. Nucleic Acids Res, 2018 Apr 20. PMID 29447387, Free PMC Article
  2. A Toolbox for Efficient Proximity-Dependent Biotinylation in Zebrafish Embryos. Rosenthal SM, et al. Mol Cell Proteomics, 2021. PMID 34332124, Free PMC Article
  3. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables protein-macromolecule adaptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within mRNA transport IEA
Inferred from Electronic Annotation
more info
  
involved_in nuclear pore organization IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in nuclear membrane IEA
Inferred from Electronic Annotation
more info
  
part_of nuclear pore IEA
Inferred from Electronic Annotation
more info
  
part_of nuclear pore transmembrane ring IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
nucleoporin NDC1
Names
transmembrane protein 48

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199943.1 → NP_956237.1  nucleoporin NDC1

    See identical proteins and their annotated locations for NP_956237.1

    Status: PROVISIONAL

    Source sequence(s)
    BC053915
    UniProtKB/Swiss-Prot
    Q7SZC5
    Related
    ENSDARP00000016349.8, ENSDART00000025120.9
    Conserved Domains (1) summary
    pfam09531
    Location:13 → 663
    Ndc1_Nup; Nucleoporin protein Ndc1-Nup

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007113.7 Reference GRCz11 Primary Assembly

    Range
    26576832..26590623 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009298544.3 → XP_009296819.1  nucleoporin NDC1 isoform X1

    UniProtKB/TrEMBL
    A0A8M3AXA1
    Conserved Domains (1) summary
    pfam09531
    Location:13 → 646
    Ndc1_Nup; Nucleoporin protein Ndc1-Nup
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7SZC5.1 GenPept UniProtKB/Swiss-Prot:Q7SZC5

Gene LinkOut

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