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    Ddr Discoidin domain receptor [ Drosophila melanogaster ]

    Gene ID: 3346209, updated on 9-May-2012
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    Summary

    Official Symbol
    Ddrprovided by Flybase
    Official Full Name
    Discoidin domain receptorprovided by Flybase
    Primary source
    FLYBASE:FBgn0053531
    Locus tag
    Dmel_CG33531
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG11573; CG13985; CG33531; CG9488; CG9490; CT33540; DDR; Dmel\CG33531
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    Genomic context

    Location :
    26C1-26C2
    Sequence :
    Chromosome: 2L; NT_033779.4 (6253123..6322251)
    See Ddr in Epigenomics, MapViewer

    Chromosome 2L - NT_033779.4Genomic Context describing neighboring genes Neighboring gene CG34380 gene product from transcript CG34380-RC Neighboring gene UDP-glycosyltransferase 37b1 Neighboring gene CG9486 gene product from transcript CG9486-RA Neighboring gene CG13983 gene product from transcript CG13983-RA Neighboring gene CG42735 gene product from transcript CG42735-RA Neighboring gene CG13984 gene product from transcript CG13984-RA Neighboring gene CG9491 gene product from transcript CG9491-RB Neighboring gene CG9493 gene product from transcript CG9493-RA

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Accelerated sequence divergence of conserved genomic elements in Drosophila melanogaster. Holloway AK, et al. Genome Res, 2008 Oct. PMID 18583644.
    2. Sequence finishing and mapping of Drosophila melanogaster heterochromatin. Hoskins RA, et al. Science, 2007 Jun 15. PMID 17569867.
    3. The Release 5.1 annotation of Drosophila melanogaster heterochromatin. Smith CD, et al. Science, 2007 Jun 15. PMID 17569856.
    4. Combined evidence annotation of transposable elements in genome sequences. Quesneville H, et al. PLoS Comput Biol, 2005 Jul. PMID 16110336.
    5. Genome-wide survey of protein kinases required for cell cycle progression. Bettencourt-Dias M, et al. Nature, 2004 Dec 23. PMID 15616552.

    See all (14) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:77927 BioGRID:59251 CG14219    BioGRID  PubMed Two-hybrid 
    BioGRID:77927 BioGRID:61285 CG17470    BioGRID  PubMed Two-hybrid 
    BioGRID:77927 BioGRID:66784 CG3061    BioGRID  PubMed Two-hybrid 
    BioGRID:77927 BioGRID:66004 CG31482    BioGRID  PubMed Two-hybrid 
    BioGRID:77927 BioGRID:64354 CG7188    BioGRID  PubMed Two-hybrid 
    BioGRID:77927 BioGRID:69078 Met75Ca    BioGRID  PubMed Two-hybrid 
    BioGRID:77927 BioGRID:69077 Met75Cb    BioGRID  PubMed Two-hybrid 
    BioGRID:77927 BioGRID:65893 RpL13A    BioGRID  PubMed Two-hybrid 
    BioGRID:77927 BioGRID:68014 RpL27    BioGRID  PubMed Two-hybrid 
    BioGRID:77927 BioGRID:62326 RpS23    BioGRID  PubMed Two-hybrid 
    BioGRID:77927 BioGRID:60502 RpS27A    BioGRID  PubMed Two-hybrid 
    BioGRID:77927 BioGRID:65557 Spc105R    BioGRID  PubMed Two-hybrid 
    BioGRID:77927 BioGRID:72725 Sulf1    BioGRID  PubMed Two-hybrid 
    BioGRID:77927 BioGRID:68626 bip2    BioGRID  PubMed Two-hybrid 
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    General gene information

    Markers

    Homology

    • Homologs of the Ddr gene: The Ddr gene is conserved in human, chimpanzee, , dog, cow, mouse, rat, chicken, and zebrafish.

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    protein tyrosine kinase activity NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    transmembrane receptor protein tyrosine kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    protein phosphorylation NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    transmembrane receptor protein tyrosine kinase signaling pathway ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    integral to membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
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    General protein information

    Preferred Names
    CG33531 gene product from transcript CG33531-RA
    Names
    CG33531-PA
    CG33531-PB
    Ddr-PA
    Ddr-PB
    discoidin domain receptor
    NP_001014474.2
    NP_001162895.1
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.4

      Range
      6253123..6322251
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001014474.3 → NP_001014474.2  discoidin domain receptor, isoform A [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q59DZ7
      Related
      FBpp0078876, FBtr0091497
      Conserved Domains (4) summary
      cd00057
      Location:108 – 261
      Blast Score: 205
      FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
      cd05051
      Location:753 – 1050
      Blast Score: 1288
      PTKc_DDR; Catalytic domain of the Protein Tyrosine Kinases, Discoidin Domain Receptors
      smart00219
      Location:759 – 1048
      Blast Score: 710
      TyrKc; Tyrosine kinase, catalytic domain
      smart00231
      Location:106 – 262
      Blast Score: 184
      FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain

    2. NM_001169424.1 → NP_001162895.1  discoidin domain receptor, isoform B [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JHA2
      Related
      FBpp0290520, FBtr0301305
      Conserved Domains (2) summary
      cd00057
      Location:108 – 261
      Blast Score: 196
      FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
      smart00231
      Location:106 – 262
      Blast Score: 175
      FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AE014134.5 AAX52658.2
    genomic AE014134.5 ACZ94186.1
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    Additional Links

    Gene LinkOut

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