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FOXN2 forkhead box N2 [ Homo sapiens (human) ]

Gene ID: 3344, updated on 26-May-2016
Official Symbol
FOXN2provided by HGNC
Official Full Name
forkhead box N2provided by HGNC
Primary source
HGNC:HGNC:5281
See related
Ensembl:ENSG00000170802 HPRD:00882; MIM:143089; Vega:OTTHUMG00000129168
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HTLF
Summary
This gene encodes a forkhead domain binding protein and may function in the transcriptional regulation of the human T-cell leukemia virus long terminal repeat. [provided by RefSeq, Jul 2008]
Orthologs
Location:
2p22-p16
Exon count:
10
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 2 NC_000002.12 (48314644..48379295)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (48541783..48606434)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105374591 Neighboring gene vomeronasal 1 receptor 18 pseudogene Neighboring gene uncharacterized LOC105374593 Neighboring gene uncharacterized LOC102724008 Neighboring gene protein phosphatase 1 regulatory subunit 21 Neighboring gene STON1-GTF2A1L readthrough Neighboring gene stonin 1

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
transcription factor activity, sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
skeletal muscle cell differentiation IEA
Inferred from Electronic Annotation
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
intracellular membrane-bounded organelle IDA
Inferred from Direct Assay
more info
 
nucleus IDA
Inferred from Direct Assay
more info
 
Preferred Names
forkhead box protein N2
Names
human T-cell leukemia virus enhancer factor

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_002158.3NP_002149.2  forkhead box protein N2

    See identical proteins and their annotated locations for NP_002149.2

    Status: REVIEWED

    Source sequence(s)
    AA827684, AC091485, BC063305
    Consensus CDS
    CCDS1838.1
    UniProtKB/Swiss-Prot
    P32314
    Related
    ENSP00000343633, OTTHUMP00000159451, ENST00000340553, OTTHUMT00000251240
    Conserved Domains (1) summary
    cd00059
    Location:112190
    FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p2 Primary Assembly

    Range
    48314644..48379295
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011532808.1XP_011531110.1  

    See identical proteins and their annotated locations for XP_011531110.1

    UniProtKB/Swiss-Prot
    P32314
    Conserved Domains (1) summary
    cd00059
    Location:112190
    FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
  2. XM_005264283.1XP_005264340.1  

    See identical proteins and their annotated locations for XP_005264340.1

    UniProtKB/Swiss-Prot
    P32314
    Conserved Domains (1) summary
    cd00059
    Location:112190
    FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
  3. XM_005264282.1XP_005264339.1  

    See identical proteins and their annotated locations for XP_005264339.1

    UniProtKB/Swiss-Prot
    P32314
    Conserved Domains (1) summary
    cd00059
    Location:112190
    FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
  4. XM_006712001.2XP_006712064.1  

    See identical proteins and their annotated locations for XP_006712064.1

    UniProtKB/Swiss-Prot
    P32314
    Conserved Domains (1) summary
    cd00059
    Location:112190
    FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
  5. XM_006712002.2XP_006712065.1  

    See identical proteins and their annotated locations for XP_006712065.1

    UniProtKB/Swiss-Prot
    P32314
    Conserved Domains (1) summary
    cd00059
    Location:112190
    FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...

Alternate CHM1_1.1

Genomic

  1. NC_018913.2 Alternate CHM1_1.1

    Range
    48471985..48536626
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)