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    Uch Ubiquitin carboxy-terminal hydrolase [ Drosophila melanogaster ]

    Gene ID: 33397, updated on 8-Jan-2012
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    Summary

    Official Symbol
    Uchprovided by Flybase
    Official Full Name
    Ubiquitin carboxy-terminal hydrolaseprovided by Flybase
    Primary source
    FLYBASE:FBgn0010288
    Locus tag
    Dmel_CG4265
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG4265; Dmel\CG4265; UBL; uch; UCH; uch-D; UCH-D; UCH-D19
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    Genomic context

    Location :
    22D4-22D4
    Sequence :
    Chromosome: 2L; NT_033779.4 (2212738..2214179, complement)
    See Uch in Epigenomics, MapViewer

    Chromosome 2L - NT_033779.4Genomic Context describing neighboring genes Neighboring gene CG33124 gene product from transcript CG33124-RC Neighboring gene CG15385 gene product from transcript CG15385-RA Neighboring gene CG34174 gene product from transcript CG34174-RA Neighboring gene CG10880 gene product from transcript CG10880-RA Neighboring gene CG15386 gene product from transcript CG15386-RA

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. A microtubule interactome: complexes with roles in cell cycle and mitosis. Hughes JR, et al. PLoS Biol, 2008 Apr 22. PMID 18433294.
    2. Genome-wide view of cell fate specification: ladybird acts at multiple levels during diversification of muscle and heart precursors. Junion G, et al. Genes Dev, 2007 Dec 1. PMID 18056427.
    3. Sequence finishing and mapping of Drosophila melanogaster heterochromatin. Hoskins RA, et al. Science, 2007 Jun 15. PMID 17569867.
    4. The Release 5.1 annotation of Drosophila melanogaster heterochromatin. Smith CD, et al. Science, 2007 Jun 15. PMID 17569856.
    5. Combined evidence annotation of transposable elements in genome sequences. Quesneville H, et al. PLoS Comput Biol, 2005 Jul. PMID 16110336.

    See all (17) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:59626 BioGRID:58346 CG3099    BioGRID  PubMed Two-hybrid 
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    General gene information

    Homology

    • Homologs of the Uch gene: The Uch gene is conserved in human, dog, cow, mouse, rat, chicken, zebrafish, mosquito, S.pombe, S.cerevisiae, K.lactis, E.gossypii, M.grisea, N.crassa, A.thaliana, rice, and P.falciparum.

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    ubiquitin thiolesterase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    ubiquitin thiolesterase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    ubiquitin thiolesterase activity NAS
    Non-traceable Author Statement
    more info
    		  
    Process Evidence Code Pubs
    protein deubiquitination IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    protein deubiquitination ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    microtubule associated complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
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    General protein information

    Preferred Names
    CG4265 gene product from transcript CG4265-RA
    Names
    CG4265-PA
    CG4265-PB
    Uch-PA
    Uch-PB
    ubiquitin carboxy-terminal hydrolase
    ubiquitin carboxyl terminal hydrolase
    NP_001188681.1
    NP_476940.1
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.4

      Range
      2212738..2214179, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_057592.3 → NP_476940.1  ubiquitin carboxy-terminal hydrolase, isoform A [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P35122
      Related
      FBpp0077516, FBtr0077844
      Conserved Domains (1) summary
      cd09616
      Location:4 – 222
      Blast Score: 890
      Peptidase_C12_UCH_L1_L3; Cysteine peptidase C12 containing ubiquitin carboxyl-terminal hydrolase (UCH) families L1 and L3

    2. NM_001201752.1 → NP_001188681.1  ubiquitin carboxy-terminal hydrolase, isoform B [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P35122
      Conserved Domains (1) summary
      cd09616
      Location:4 – 222
      Blast Score: 890
      Peptidase_C12_UCH_L1_L3; Cysteine peptidase C12 containing ubiquitin carboxyl-terminal hydrolase (UCH) families L1 and L3
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AE014134.5 AAF51291.1
    genomic AE014134.5 ADV36932.1
    mRNA AF145600.1 AAD38575.1
    Protein Accession Links
    GenePept Link UniProtKB Link
    Q9V417.1 GenPept
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    Additional Links

    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

      Supplemental Content