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    CG4552 [ Drosophila melanogaster ]

    Gene ID: 33289, updated on 9-May-2012

    Summary

    Official Symbol
    CG4552provided by Flybase
    Primary source
    FLYBASE:FBgn0031304
    Locus tag
    Dmel_CG4552
    Gene type
    protein coding
    RNA name
    CG4552
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG4552

    Genomic context

    Location :
    21F1-21F1
    Sequence :
    Chromosome: 2L; NT_033779.4 (1129235..1132413)
    See CG4552 in Epigenomics, MapViewer

    Chromosome 2L - NT_033779.4Genomic Context describing neighboring genes Neighboring gene CG14340 gene product from transcript CG14340-RA Neighboring gene Pinocchio Neighboring gene CG4715 gene product from transcript CG4715-RA Neighboring gene CG4577 gene product from transcript CG4577-RA Neighboring gene CG4726 gene product from transcript CG4726-RA

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:59542 BioGRID:58854 CG8128    BioGRID  PubMed Two-hybrid 
    BioGRID:59542 BioGRID:60245 CG8455    BioGRID  PubMed Two-hybrid 
    BioGRID:59542 BioGRID:61846 Orc6    BioGRID  PubMed Two-hybrid 
    BioGRID:59542 BioGRID:57919 Pp2C1    BioGRID  PubMed Two-hybrid 

    General gene information

    Homology

    • Homologs of the CG4552 gene: The CG4552 gene is conserved in human, chimpanzee, , dog, cow, mouse, chicken, zebrafish, mosquito, and C.elegans.

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    Rab GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    phagocytosis, engulfment IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of Rab GTPase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    intracellular IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    CG4552 gene product from transcript CG4552-RA
    Names
    CG4552
    CG4552-PA

    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.4

      Range
      1129235..1132413
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_134725.1NP_608569.1  CG4552 [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VPW9
      Related
      FBpp0077621, FBtr0077956
      Conserved Domains (2) summary
      cl02495
      Location:34233
      Blast Score: 299
      RabGAP-TBC; Rab-GTPase-TBC domain
      cl00125
      Location:330429
      Blast Score: 90
      RHOD; Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins ...

    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AE014134.5 AAF51416.2
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VPW9.1 GenPept

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