My NCBISign In

Display Settings:

Format

Send to:

Choose Destination

    Clp Clipper [ Drosophila melanogaster ]

    Gene ID: 33259, updated on 10-May-2012
    Help top of page

    Summary

    Official Symbol
    Clpprovided by Flybase
    Official Full Name
    Clipperprovided by Flybase
    Primary source
    FLYBASE:FBgn0015621
    Locus tag
    Dmel_CG3642
    Gene type
    protein coding
    RNA name
    clipper
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    c6a; CG3642; clp; CLP; CPSF30; Dmel\CG3642; Ssb-c6a
    Help top of page

    Genomic context

    Location :
    21E2-21E2
    Sequence :
    Chromosome: 2L; NT_033779.4 (819964..821209)
    See Clp in Epigenomics, MapViewer

    Chromosome 2L - NT_033779.4Genomic Context describing neighboring genes Neighboring gene peroxin 12 Neighboring gene CG15880 gene product from transcript CG15880-RA Neighboring gene CG3876 gene product from transcript CG3876-RA Neighboring gene CG3662 gene product from transcript CG3662-RB Neighboring gene CG3862 gene product from transcript CG3862-RA Neighboring gene dreadlocks

    Help top of page

    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
    Helptop of page

    Bibliography

    Related articles in PubMed

    1. A subset of Drosophila integrator proteins is essential for efficient U7 snRNA and spliceosomal snRNA 3'-end formation. Ezzeddine N, et al. Mol Cell Biol, 2011 Jan. PMID 21078872.
    2. A core complex of CPSF73, CPSF100, and Symplekin may form two different cleavage factors for processing of poly(A) and histone mRNAs. Sullivan KD, et al. Mol Cell, 2009 May 15. PMID 19450530.
    3. A genome-wide RNA interference screen reveals that variant histones are necessary for replication-dependent histone pre-mRNA processing. Wagner EJ, et al. Mol Cell, 2007 Nov 30. PMID 18042462.
    4. Sequence finishing and mapping of Drosophila melanogaster heterochromatin. Hoskins RA, et al. Science, 2007 Jun 15. PMID 17569867.
    5. The Release 5.1 annotation of Drosophila melanogaster heterochromatin. Smith CD, et al. Science, 2007 Jun 15. PMID 17569856.

    See all (16) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
    Help top of page

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:59513 BioGRID:66072 CG10032    BioGRID  PubMed Two-hybrid 
    BioGRID:59513 BioGRID:64799 CG17666    BioGRID  PubMed Two-hybrid 
    BioGRID:59513 BioGRID:76749 CG32638    BioGRID  PubMed Two-hybrid 
    BioGRID:59513 BioGRID:72704 CG34168    BioGRID  PubMed Two-hybrid 
    BioGRID:59513 BioGRID:60574 CG43129    BioGRID  PubMed Two-hybrid 
    BioGRID:59513 BioGRID:65788 Fip1    BioGRID  PubMed Two-hybrid 
    BioGRID:59513 BioGRID:59097 GS    BioGRID  PubMed Two-hybrid 
    BioGRID:59513 BioGRID:58290 HP1b    BioGRID  PubMed Two-hybrid 
    BioGRID:59513 BioGRID:58668 IP3K2    BioGRID  PubMed Two-hybrid 
    BioGRID:59513 BioGRID:66080 Mst84Da    BioGRID  PubMed Two-hybrid 
    BioGRID:59513 BioGRID:66079 Mst84Db    BioGRID  PubMed Two-hybrid 
    BioGRID:59513 BioGRID:66078 Mst84Dc    BioGRID  PubMed Two-hybrid 
    BioGRID:59513 BioGRID:66771 Mst87F    BioGRID  PubMed Two-hybrid 
    BioGRID:59513 BioGRID:69024 RFeSP    BioGRID  PubMed Two-hybrid 
    BioGRID:59513 BioGRID:60808 ics    BioGRID  PubMed Two-hybrid 
    BioGRID:59513 BioGRID:65410 l(3)76BDm    BioGRID  PubMed Two-hybrid 
    BioGRID:59513 BioGRID:60845 nimC1    BioGRID  PubMed Two-hybrid 
    BioGRID:59513 BioGRID:68196 wdb    BioGRID  PubMed Two-hybrid 
    Help top of page

    General gene information

    Homology

    • Homologs of the Clp gene: The Clp gene is conserved in human, chimpanzee, , dog, cow, mouse, rat, chicken, zebrafish, and C.elegans.

    Pathways from BioSystems

    • mRNA processing, organism-specific biosystem (from WikiPathways)
      mRNA processing, organism-specific biosystemThis process describes the conversion of precursor messenger RNA into mature messenger RNA (mRNA). The pre-mRNA molecule undergoes three main modifications. These modifications are 5' capping, 3' pol...
    • mRNA surveillance pathway, organism-specific biosystem (from KEGG)
      mRNA surveillance pathway, organism-specific biosystemThe mRNA surveillance pathway is a quality control mechanism that detects and degrades abnormal mRNAs. These pathways include nonsense-mediated mRNA decay (NMD), nonstop mRNA decay (NSD), and no-go ...
    • mRNA surveillance pathway, conserved biosystem (from KEGG)
      mRNA surveillance pathway, conserved biosystemThe mRNA surveillance pathway is a quality control mechanism that detects and degrades abnormal mRNAs. These pathways include nonsense-mediated mRNA decay (NMD), nonstop mRNA decay (NSD), and no-go ...

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    endoribonuclease activity IDA
    Inferred from Direct Assay
    more info
    		  
    nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    mRNA cleavage ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    mRNA polyadenylation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    neurogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		  
    Component Evidence Code Pubs
    mRNA cleavage and polyadenylation specificity factor complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Help top of page

    General protein information

    Preferred Names
    CG3642 gene product from transcript CG3642-RA
    Names
    CG3642-PA
    Clp-PA
    clipper
    single stranded-binding protein c6a
    Help top of page

    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.4

      Range
      819964..821209
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_057808.2 → NP_477156.1  clipper [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VPT8
      Related
      FBpp0077676, FBtr0078011
      Conserved Domains (2) summary
      COG5084
      Location:12 – 175
      Blast Score: 254
      YTH1; Cleavage and polyadenylation specificity factor (CPSF) Clipper subunit and related makorin family Zn-finger proteins [General function prediction only]
      cl11592
      Location:66 – 90
      Blast Score: 83
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
    Help top of page

    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AE014134.5 AAF51453.1
    mRNA BT025009.1 ABE01239.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VPT8.1 GenPept
    Help top of page

    Additional Links

    Gene LinkOut

      Supplemental Content

      Recent activity

      Clear Turn Off Turn On

      Your browsing activity is empty.

      Activity recording is turned off.

      Turn recording back on

      See more...