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    Ntf-2 Nuclear transport factor-2 [ Drosophila melanogaster ]

    Gene ID: 33078, updated on 10-May-2012
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    Summary

    Official Symbol
    Ntf-2provided by Flybase
    Official Full Name
    Nuclear transport factor-2provided by Flybase
    Primary source
    FLYBASE:FBgn0031145
    Locus tag
    Dmel_CG1740
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:GM08921; CG1740; Dmel\CG1740; dmNTF2; Dntf-2; DNTF-2; Dntf2; l(1)G0086; l(1)G0125; l(1)G0337; l(1)G0428; ntf-2; NTF-2; ntf2; Ntf2
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    Genomic context

    Location :
    19E7-19E7
    Sequence :
    Chromosome: X; NC_004354.3 (20906501..20910263)
    See Ntf-2 in Epigenomics, MapViewer

    Chromosome X - NC_004354.3Genomic Context describing neighboring genes Neighboring gene CG1532 gene product from transcript CG1532-RA Neighboring gene CG1529 gene product from transcript CG1529-RA Neighboring gene CG15449 gene product from transcript CG15449-RA Neighboring gene Microsomal glutathione S-transferase-like

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. A protein complex network of Drosophila melanogaster. Guruharsha KG, et al. Cell, 2011 Oct 28. PMID 22036573.
    2. Evolution of alternative splicing in newly evolved genes of Drosophila. Zhan Z, et al. Gene, 2011 Jan 1. PMID 20851753.
    3. Convergently recruited nuclear transport retrogenes are male biased in expression and evolving under positive selection in Drosophila. Tracy C, et al. Genetics, 2010 Apr. PMID 20065068.
    4. X-linked variation in immune response in Drosophila melanogaster. Hill-Burns EM, et al. Genetics, 2009 Dec. PMID 19822734.
    5. The nuclear transport machinery as a regulator of Drosophila development. Mason DA, et al. Semin Cell Dev Biol, 2009 Jul. PMID 19508860.

    See all (26) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. the possibility that Dntf-2r and ran-like might be involved in genomic conflicts during spermatogenesis
      Title: Convergently recruited nuclear transport retrogenes are male biased in expression and evolving under positive selection in Drosophila.
    2. Nuclear transport factor 2, specifically required in the development of the eye and in the immune response
      Title: The Drosophila homolog of NTF-2, the nuclear transport factor-2, is essential for immune response.
    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:59365 BioGRID:67495 AP-2sigma    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:59365 BioGRID:59312 AnnX    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:59365 BioGRID:64774 CG10638    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:59365 BioGRID:60093 CG11327    BioGRID  PubMed Two-hybrid 
    BioGRID:59365 BioGRID:63895 CG11505    BioGRID  PubMed Two-hybrid 
    BioGRID:59365 BioGRID:58732 CG11581    BioGRID  PubMed Two-hybrid 
    BioGRID:59365 BioGRID:60371 CG13113    BioGRID  PubMed Two-hybrid 
    BioGRID:59365 BioGRID:64811 CG14119    BioGRID  PubMed Two-hybrid 
    BioGRID:59365 BioGRID:58768 CG14410    BioGRID  PubMed Two-hybrid 
    BioGRID:59365 BioGRID:66530 CG14715    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:59365 BioGRID:61537 CG1707    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:59365 BioGRID:58268 CG2004    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:59365 BioGRID:63701 CG2199    BioGRID  PubMed Two-hybrid 
    BioGRID:59365 BioGRID:63206 CG2852    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:59365 BioGRID:59694 CG2862    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:59365 BioGRID:77425 CG31917    BioGRID  PubMed Two-hybrid 
    BioGRID:59365 BioGRID:57730 CG3630    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:59365 BioGRID:68405 CG42557    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:59365 BioGRID:67420 CG5466    BioGRID  PubMed Two-hybrid 
    BioGRID:59365 BioGRID:64666 CG6084    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:59365 BioGRID:64382 CG6776    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:59365 BioGRID:59176 CG6891    BioGRID  PubMed Two-hybrid 
    BioGRID:59365 BioGRID:63816 CG8993    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:59365 BioGRID:59687 CG9894    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:59365 BioGRID:66325 Crc    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:59365 BioGRID:58935 Cyp1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:59365 BioGRID:61363 Df31    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:59365 BioGRID:59591 Eno    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:59365 BioGRID:63078 Fkbp13    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:59365 BioGRID:66533 Ho    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:59365 BioGRID:58274 Moe    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:59365 BioGRID:68416 Nlp    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:59365 BioGRID:64973 Pdi    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:59365 BioGRID:61917 Prx2540-2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:59365 BioGRID:65446 RhoGDI    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:59365 BioGRID:64260 Sh3beta    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:59365 BioGRID:64623 Sod    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:59365 BioGRID:58696 Tango2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:59365 BioGRID:60380 Trx-2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:59365 BioGRID:58221 Trxr-1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:59365 BioGRID:61505 Tsp42Eg    BioGRID  PubMed Two-hybrid 
    BioGRID:59365 BioGRID:59467 alpha-Adaptin    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:59365 BioGRID:68580 awd    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:59365 BioGRID:57877 cib    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:59365 BioGRID:59637 gho    BioGRID  PubMed Two-hybrid 
    BioGRID:59365 BioGRID:65450 hale    BioGRID  PubMed Two-hybrid 
    BioGRID:59365 BioGRID:67557 how    BioGRID  PubMed Two-hybrid 
    BioGRID:59365 BioGRID:67018 mtSSB    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:59365 BioGRID:58570 regucalcin    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:59365 BioGRID:76064 sav    BioGRID  PubMed Two-hybrid 
    BioGRID:59365 BioGRID:59109 scu    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:59365 BioGRID:61853 sec24    BioGRID  PubMed Two-hybrid 
    BioGRID:59365 BioGRID:60130 smt3    BioGRID  PubMed Affinity Capture-MS 
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    General gene information

    Homology

    • Homologs of the Ntf-2 gene: The Ntf-2 gene is conserved in human, chimpanzee, , dog, cow, rat, chicken, zebrafish, mosquito, and C.elegans.

    mobile_element

    • Loc: 20907986-20908316 mobile_element_type = transposon:INE-1{}5581

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    protein transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    positive regulation of antimicrobial peptide biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    protein import into nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    protein import into nucleus NAS
    Non-traceable Author Statement
    more info
    		  
    Component Evidence Code Pubs
    intracellular IEA
    Inferred from Electronic Annotation
    more info
    		  
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    General protein information

    Preferred Names
    CG1740 gene product from transcript CG1740-RA
    Names
    CG1740-PA
    CG1740-PB
    Ntf-2-PA
    Ntf-2-PB
    nuclear transport factor-2
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.3

      Range
      20906501..20910263
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_134578.2 → NP_608422.1  nuclear transport factor-2, isoform A [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VRD6
      Related
      FBpp0076934, FBtr0077241
      Conserved Domains (1) summary
      cd00780
      Location:6 – 125
      Blast Score: 288
      NTF2; Nuclear transport factor 2 (NTF2) domain plays an important role in the trafficking of macromolecules, ions and small molecules between the cytoplasm and nucleus. This bi-directional transport of macromolecules across the nuclear envelope requires many ...

    2. NM_001103570.1 → NP_001097040.1  nuclear transport factor-2, isoform B [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8JUT4
      Related
      FBpp0111920, FBtr0113007
      Conserved Domains (1) summary
      cd00780
      Location:6 – 124
      Blast Score: 278
      NTF2; Nuclear transport factor 2 (NTF2) domain plays an important role in the trafficking of macromolecules, ions and small molecules between the cytoplasm and nucleus. This bi-directional transport of macromolecules across the nuclear envelope requires many ...
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    mRNA AY673973.1 AAV87140.1
    mRNA AY094761.1 AAM11114.1
    mRNA AY531117.1 AAS98195.1
    genomic AE014298.4 AAF50866.1
    genomic AE014298.4 ABW09457.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VRD6.1 GenPept
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    Additional Links

    Gene LinkOut

      Supplemental Content