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    HSPA1B heat shock 70kDa protein 1B [ Homo sapiens ]

    Gene ID: 3304, updated on 19-May-2012
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    Summary

    Official Symbol
    HSPA1Bprovided by HGNC
    Official Full Name
    heat shock 70kDa protein 1Bprovided by HGNC
    Primary source
    HGNC:5233
    Locus tag
    DAAP-21F2.7
    See related
    Ensembl:ENSG00000204388; HPRD:06784; MIM:603012; Vega:OTTHUMG00000031202
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    HSPA1A; HSP70-2; HSP70-1B; FLJ54328
    Summary
    This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins. [provided by RefSeq, Jul 2008]
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    Genomic context

    Location :
    6p21.3
    Sequence :
    Chromosome: 6; NC_000006.11 (31795512..31798031)
    See HSPA1B in Epigenomics, MapViewer

    Chromosome 6 - NC_000006.11Genomic Context describing neighboring genes Neighboring gene heat shock 70kDa protein 1-like Neighboring gene heat shock 70kDa protein 1A Neighboring gene chromosome 6 open reading frame 48 Neighboring gene small nucleolar RNA, C/D box 48 Neighboring gene small nucleolar RNA, C/D box 52

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Defective nuclear localization of Hsp70 is associated with dyserythropoiesis and GATA-1 cleavage in myelodysplastic syndromes. Frisan E, et al. Blood, 2012 Feb 9. PMID 22160620.
    2. Variations in HSPA1B at 6p21.3 are associated with lung cancer risk and prognosis in Chinese populations. Guo H, et al. Cancer Res, 2011 Dec 15. PMID 22037874.
    3. Ubiquitin ligase substrate identification through quantitative proteomics at both the protein and peptide levels. Lee KA, et al. J Biol Chem, 2011 Dec 2. PMID 21987572.
    4. Global identification of modular cullin-RING ligase substrates. Emanuele MJ, et al. Cell, 2011 Oct 14. PMID 21963094.
    5. Interaction of the ARF tumor suppressor with cytosolic HSP70 contributes to its autophagy function. Pimkina J, et al. Cancer Biol Ther, 2011 Sep 15. PMID 21738007.

    See all (138) citations in PubMed

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. Data show that expression of a nucleus-targeted mutant of Hsp70 protects GATA-1 and rescues Expression of a nucleus-targeted mutant of Hsp70 protects GATA-1 and rescues myelodysplastic syndromes erythroid cell differentiation.
      Title: Defective nuclear localization of Hsp70 is associated with dyserythropoiesis and GATA-1 cleavage in myelodysplastic syndromes.
    2. Fndings show that the HSPA1B variants are associated with lung cancer risk and survival.
      Title: Variations in HSPA1B at 6p21.3 are associated with lung cancer risk and prognosis in Chinese populations.
    3. HSP70 as a critical regulator of ARF-mediated autophagy, and reinforce the importance of mitochondrial trafficking of ARF for its autophagy function
      Title: Interaction of the ARF tumor suppressor with cytosolic HSP70 contributes to its autophagy function.
    4. The results clearly show that certain human tissues constitutively express varying levels of HSPA1B protein in a highly differentiated way.
      Title: Differential expression of HSPA1 and HSPA2 proteins in human tissues; tissue microarray-based immunohistochemical study.
    5. Results indicate that HSP70 alleles are associated with the susceptibility to and severity of CWP, and may be involved in the pathogenesis and development of CWP in the southwestern Chinese Han population.
      Title: Polymorphisms in heat-shock protein 70 genes are associated with coal workers' pneumoconiosis in southwestern China.
    6. DNA sequence variation for the highly homologous HSPA1A and HSPA1B genes in the major histocompatibility complex on chromosome 6p21, was studied.
      Title: Genetic determinants of HSP70 gene expression following heat shock.
    7. HSP70-2 expression is up-regulated in response to hypoxia.
      Title: [Hypoxia induces heat shock protein HSP70-2 expression in a HIF-1 dependent manner].
    8. Results are likely to indicate a primary association between HSPA1B gene polymorphisms with childhood acute lymphoblastic leukemia.
      Title: HLA complex-linked heat shock protein genes and childhood acute lymphoblastic leukemia susceptibility.
    9. HSP70-2 down-regulation induces apoptosis of HCC cells through the mitochondrial apoptotic pathway.
      Title: [Inhibition of HSP70-2 expression by RNA interference induces apoptosis of human hepatocellular carcinoma cells].
    10. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
      Title: Epistasis between a set of variations located in the TAAR6 and HSP-70 genes toward schizophrenia and response to antipsychotic treatment.
    Submit: New GeneRIF Correction See all (53)
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    Phenotypes

    Review eQTL and phenotype association data in this region using PheGenI

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    HIV-1 protein interactions

    Protein Gene Interaction Pubs
    Envelope surface glycoprotein gp120 env Over expression of hsp70 with a herpes viral amplicon vector protects cultured hippocampal rat neurons from gp120 neurotoxicity PubMed
    env The exposure of permissive CD4+ cells to HIV-1 gp120 increases the synthesis and nuclear translocation of 70kDa heat shock protein PubMed
    Pr55(Gag) gag Hsp70 co-sediments with HIV-1 capsid protein in sucrose density gradients, providing evidence that it is specifically incorporated into HIV-1 virions through an interaction with HIV-1 Gag proteins PubMed
    gag Hsp70 is incorporated into HIV-1 virions through an interaction with HIV-1 Gag PubMed
    Tat tat Hsp70 and Hsp90 and Cdc37 regulate the stabilization and folding of CDK9 as well as the assembly of an active CDK9/cyclin T1 complex responsible for P-TEFb-mediated HIV-1 Tat transactivation PubMed
    Vpr vpr HIV-1 Vpr competes with Hsp70 for binding to karyopherin alpha PubMed
    matrix gag Hsp70 facilitates nuclear import of HIV-1 preintegration complexes by stimulating the binding of HIV-1 Matrix to karyopherin alpha PubMed

    Go to the HIV-1, Human Protein Interaction Database

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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    P08107 O95831 AIFM1    HPRD  PubMed  
    P08107 Q99933 BAG1    HPRD  PubMed  
    P08107 Q6XZF7 DNMBP    HPRD  PubMed  
    P08107 HSPBP1 HSPBP1    HPRD  PubMed  
    P08107 Bcl XL binding protein v68 PGAM5    HPRD  PubMed  
    P08107 Q9UNE7 STUB1    HPRD  PubMed  
    P08107 Q6EEV6 SUMO4    HPRD  PubMed  
    P08107 P31946 YWHAB    HPRD  PubMed  
    P08107 P63104 YWHAZ    HPRD  PubMed  
    BioGRID:109536 BioGRID:114342 BANF1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:109536 BioGRID:114023 DYRK2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:109536 BioGRID:108552 FGFR3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:109536 BioGRID:128154 PGAM5    BioGRID  PubMed Two-hybrid 
    BioGRID:109536 BioGRID:113188 SUMO1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:109536 BioGRID:112497 SUMO2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:109536 BioGRID:132223 SUMO4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:109536 BioGRID:113164 UBC    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:109536 BioGRID:113361 YWHAB    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:109536 BioGRID:113366 YWHAZ    BioGRID  PubMed Affinity Capture-MS 
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    General gene information

    Markers

    Genotypes

    Pathways from BioSystems

    • Androgen Receptor Signaling Pathway, organism-specific biosystem (from WikiPathways)
      Androgen Receptor Signaling Pathway, organism-specific biosystemThe androgen receptor is a member of the nuclear receptor family of ligand activated transcription factors. These receptors bind to steroid hormones, thyroid hormone, retinoids and vitamin D among ot...
    • Antigen processing and presentation, organism-specific biosystem (from KEGG)
      Antigen processing and presentation, organism-specific biosystem
      Antigen processing and presentation
    • Antigen processing and presentation, conserved biosystem (from KEGG)
      Antigen processing and presentation, conserved biosystem
      Antigen processing and presentation
    • Apoptosis Modulation by HSP70, organism-specific biosystem (from WikiPathways)
      Apoptosis Modulation by HSP70, organism-specific biosystem
      Apoptosis Modulation by HSP70
    • Destabilization of mRNA by AUF1 (hnRNP D0), organism-specific biosystem (from REACTOME)
      Destabilization of mRNA by AUF1 (hnRNP D0), organism-specific biosystemAUF1 (hnRNP D0) dimers bind U-rich regions of AU-rich elements (AREs) in the 3' untranslated regions of mRNAs. The binding causes AUF1 dimers to assemble into higher order tetrameric complexes. Dipho...
    • Direct p53 effectors, organism-specific biosystem (from Pathway Interaction Database)
      Direct p53 effectors, organism-specific biosystem
      Direct p53 effectors
    • Disease, organism-specific biosystem (from REACTOME)
      Disease, organism-specific biosystemBiological processes are captured in Reactome by identifying the molecules (DNA, RNA, protein, small molecules) involved in them and describing the details of their interactions. From this molecular ...
    • Endocytosis, organism-specific biosystem (from KEGG)
      Endocytosis, organism-specific biosystemEndocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins en...
    • Endocytosis, conserved biosystem (from KEGG)
      Endocytosis, conserved biosystemEndocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins en...
    • Epstein-Barr virus infection, organism-specific biosystem (from KEGG)
      Epstein-Barr virus infection, organism-specific biosystemEpstein-Barr virus (EBV) is a ubiquitous human herpesvirus that is associated with oncogenesis. EBV infection to primary human B lymphocytes leads to induction of EBV-specific HLA-restricted cytotoxi...
    • Epstein-Barr virus infection, conserved biosystem (from KEGG)
      Epstein-Barr virus infection, conserved biosystemEpstein-Barr virus (EBV) is a ubiquitous human herpesvirus that is associated with oncogenesis. EBV infection to primary human B lymphocytes leads to induction of EBV-specific HLA-restricted cytotoxi...
    • Export of Viral Ribonucleoproteins from Nucleus, organism-specific biosystem (from REACTOME)
      Export of Viral Ribonucleoproteins from Nucleus, organism-specific biosystemInfluenza genomic RNA (vRNA), synthesized in the nucleus of the infected host cell, is packaged into ribonucleoprotein (RNP) complexes containing viral polymerase proteins and NP (nucleocapsid). NP ...
    • FOXM1 transcription factor network, organism-specific biosystem (from Pathway Interaction Database)
      FOXM1 transcription factor network, organism-specific biosystem
      FOXM1 transcription factor network
    • Gene Expression, organism-specific biosystem (from REACTOME)
      Gene Expression, organism-specific biosystemGene Expression covers the pathways by which genomic DNA is transcribed to yield RNA, the regulation of these transcription processes, and the pathways by which newly-made RNA Transcripts are process...
    • Influenza A, organism-specific biosystem (from KEGG)
      Influenza A, organism-specific biosystemInfluenza is a contagious respiratory disease caused by influenza virus infection. Influenza A virus is responsible for both annual seasonal epidemics and periodic worldwide pandemics. Novel strains ...
    • Influenza A, conserved biosystem (from KEGG)
      Influenza A, conserved biosystemInfluenza is a contagious respiratory disease caused by influenza virus infection. Influenza A virus is responsible for both annual seasonal epidemics and periodic worldwide pandemics. Novel strains ...
    • Influenza Infection, organism-specific biosystem (from REACTOME)
      Influenza Infection, organism-specific biosystemFor centuries influenza epidemics have plagued man, and influenza was probably the disease described by Hippocrates in 412 BC. Today it remains a major cause of morbidity and mortality worldwide with...
    • Influenza Life Cycle, organism-specific biosystem (from REACTOME)
      Influenza Life Cycle, organism-specific biosystemThe virus particle initially associates with a human host cell by binding to sialic acid-containing receptors on the host cell surface. The bound virus is endocytosed by one of four distinct mechanis...
    • Legionellosis, organism-specific biosystem (from KEGG)
      Legionellosis, organism-specific biosystemLegionellosis is a potentially fatal infectious disease caused by the bacterium Legionella pneumophila and other legionella species. Two distinct clinical and epidemiological syndromes are associated...
    • Legionellosis, conserved biosystem (from KEGG)
      Legionellosis, conserved biosystemLegionellosis is a potentially fatal infectious disease caused by the bacterium Legionella pneumophila and other legionella species. Two distinct clinical and epidemiological syndromes are associated...
    • MAPK signaling pathway, organism-specific biosystem (from WikiPathways)
      MAPK signaling pathway, organism-specific biosystemThe mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals e...
    • MAPK signaling pathway, organism-specific biosystem (from KEGG)
      MAPK signaling pathway, organism-specific biosystemThe mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals e...
    • MAPK signaling pathway, conserved biosystem (from KEGG)
      MAPK signaling pathway, conserved biosystemThe mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals e...
    • Measles, organism-specific biosystem (from KEGG)
      Measles, organism-specific biosystemMeasles virus (MV) is highly contagious virus that leads infant death worldwide. Humans are the unique natural reservoir for this virus. It causes severe immunosuppression favouring secondary bacteri...
    • Measles, conserved biosystem (from KEGG)
      Measles, conserved biosystemMeasles virus (MV) is highly contagious virus that leads infant death worldwide. Humans are the unique natural reservoir for this virus. It causes severe immunosuppression favouring secondary bacteri...
    • Protein processing in endoplasmic reticulum, organism-specific biosystem (from KEGG)
      Protein processing in endoplasmic reticulum, organism-specific biosystemThe endoplasmic reticulum (ER) is a subcellular organelle where proteins are folded with the help of lumenal chaperones. Newly synthesized peptides enter the ER via the sec61 pore and are glycosylate...
    • Protein processing in endoplasmic reticulum, conserved biosystem (from KEGG)
      Protein processing in endoplasmic reticulum, conserved biosystemThe endoplasmic reticulum (ER) is a subcellular organelle where proteins are folded with the help of lumenal chaperones. Newly synthesized peptides enter the ER via the sec61 pore and are glycosylate...
    • Regulation of mRNA Stability by Proteins that Bind AU-rich Elements, organism-specific biosystem (from REACTOME)
      Regulation of mRNA Stability by Proteins that Bind AU-rich Elements, organism-specific biosystemRNA elements rich in adenine and uracil residues (AU-rich elements) bind specific proteins which either target the RNA for degradation or, more rarely, stabilize the RNA. The activity of the AU-eleme...
    • Spliceosome, organism-specific biosystem (from KEGG)
      Spliceosome, organism-specific biosystemAfter transcription, eukaryotic mRNA precursors contain protein-coding exons and noncoding introns. In the following splicing, introns are excised and exons are joined by a macromolecular complex, th...
    • Spliceosome, conserved biosystem (from KEGG)
      Spliceosome, conserved biosystemAfter transcription, eukaryotic mRNA precursors contain protein-coding exons and noncoding introns. In the following splicing, introns are excised and exons are joined by a macromolecular complex, th...
    • Spliceosome, 35S U5-snRNP, organism-specific biosystem (from KEGG)
      Spliceosome, 35S U5-snRNP, organism-specific biosystemStructural complex; Genetic information processing; Spliceosome
    • Spliceosome, Prp19/CDC5L complex, organism-specific biosystem (from KEGG)
      Spliceosome, Prp19/CDC5L complex, organism-specific biosystemStructural complex; Genetic information processing; Spliceosome
    • Toxoplasmosis, organism-specific biosystem (from KEGG)
      Toxoplasmosis, organism-specific biosystemToxoplasma gondii is an obligate intracellular parasite that is prevalent worldwide. The tachyzoite form acquired by oral ingestion downmodulates proinflammatory signaling pathways via various mechan...
    • Toxoplasmosis, conserved biosystem (from KEGG)
      Toxoplasmosis, conserved biosystemToxoplasma gondii is an obligate intracellular parasite that is prevalent worldwide. The tachyzoite form acquired by oral ingestion downmodulates proinflammatory signaling pathways via various mechan...
    • Viral RNP Complexes in the Host Cell Nucleus, organism-specific biosystem (from REACTOME)
      Viral RNP Complexes in the Host Cell Nucleus, organism-specific biosystemViral RNP is assembled in the host cell nucleus through the interaction of full-length negative strand viral RNA (vRNA) and the viral nucleocapsid (NP) and matrix (M1) proteins. Studies of interactio...

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    protein N-terminus binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    protein binding involved in protein folding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    ubiquitin protein ligase binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    unfolded protein binding TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    RNA metabolic process TAS
    Traceable Author Statement
    more info
    		  
    anti-apoptosis TAS
    Traceable Author Statement
    more info
    		 PubMed 
    gene expression TAS
    Traceable Author Statement
    more info
    		  
    mRNA catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    mRNA metabolic process TAS
    Traceable Author Statement
    more info
    		  
    negative regulation of cell growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    negative regulation of cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    negative regulation of inclusion body assembly IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    protein refolding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    response to stress IEA
    Inferred from Electronic Annotation
    more info
    		  
    response to unfolded protein IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    cytoplasm TAS
    Traceable Author Statement
    more info
    		 PubMed 
    cytosol TAS
    Traceable Author Statement
    more info
    		  
    endoplasmic reticulum TAS
    Traceable Author Statement
    more info
    		 PubMed 
    inclusion body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    mitochondrion TAS
    Traceable Author Statement
    more info
    		 PubMed 
    nuclear speck IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    perinuclear region of cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    ribonucleoprotein complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    colocalizes_with signalosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
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    General protein information

    Preferred Names
    heat shock 70 kDa protein 1A/1B
    Names
    heat shock 70 kDa protein 1A/1B
    HSP70-1/HSP70-2
    HSP70.1/HSP70.2
    heat shock 70kD protein 1B
    heat shock 70 kDa protein 1/2
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    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_005346.4 → NP_005337.2  heat shock 70 kDa protein 1A/1B

      Status: REVIEWED

      Source sequence(s)
      AL671762, BC063507, DB015158
      Consensus CDS
      CCDS34415.1
      UniProtKB/TrEMBL
      A8K5I0
      UniProtKB/Swiss-Prot
      P08107
      Related
      ENSP00000364801, OTTHUMP00000029288, ENST00000375650, OTTHUMT00000076402
      Conserved Domains (1) summary
      PTZ00009
      Location:1 – 611
      Blast Score: 2792
      PTZ00009; heat shock 70 kDa protein; Provisional

    RefSeqs of Annotated Genomes: Build 37.3

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh37.p5 Primary Assembly

    Genomic

    1. NC_000006.11 Reference GRCh37.p5 Primary Assembly

      Range
      31795512..31798031
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh37.p5 ALT_REF_LOCI_1

    Genomic

    1. NT_167244.1 Reference GRCh37.p5 ALT_REF_LOCI_1

      Range
      3110276..3112789
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh37.p5 ALT_REF_LOCI_2

    Genomic

    1. NT_113891.2 Reference GRCh37.p5 ALT_REF_LOCI_2

      Range
      3305094..3307616
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh37.p5 ALT_REF_LOCI_3

    Genomic

    1. NT_167245.1 Reference GRCh37.p5 ALT_REF_LOCI_3

      Range
      3081099..3083618
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh37.p5 ALT_REF_LOCI_6

    Genomic

    1. NT_167248.1 Reference GRCh37.p5 ALT_REF_LOCI_6

      Range
      3089163..3091686
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate HuRef

    Genomic

    1. AC_000138.1 Alternate HuRef

      Range
      31582004..31584555
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AF134726.1 AAD21815.1
    genomic AL662834.8 (91632..94142) None
    genomic AL671762.10 (35593..38100) None
    genomic AL929592.8 (39566..42077) None
    genomic BA000025.2 BAB63299.1
    genomic CH471081.1 EAX03529.1
    genomic CR388202.9 CAQ09504.1
      CAQ09505.1
      CAQ09510.1
    genomic CR759915.6 CAQ07257.1
      CAQ07258.1
      CAQ07259.1
    genomic M24744.1 AAA59845.1
    genomic M59830.1 AAA63227.1
    mRNA AK295398.1 BAG58351.1
    mRNA AK303967.1 BAG64891.1
    mRNA AL360193.1 None
    mRNA BC001876.1 None
    mRNA BC057397.1 AAH57397.1
    mRNA BC063507.1 AAH63507.1
    mRNA DB015158.1 None
    other-genetic DQ896426.2 ABM87425.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    P08107.5 GenPept UniProtKB/Swiss-Prot:P08107
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    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Medical
    Molecular Biology Databases
    Research Materials
    Miscellaneous

      Supplemental Content

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