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CG7423 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32894, updated on 4-Apr-2024

Summary

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Official Symbol
CG7423provided by FlyBase
Primary source
FLYBASE:FBgn0030982
Locus tag
Dmel_CG7423
See related
AllianceGenome:FB:FBgn0030982
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG7423
Summary
Predicted to enable sequence-specific DNA binding activity. Predicted to be involved in positive regulation of cell growth and regulation of barbed-end actin filament capping. Predicted to be located in cytosol. Predicted to be active in cytoplasm and nucleus. Orthologous to human MTPN (myotrophin). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
18A3-18A3; 1-62 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (19082609..19083290, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (18976642..18977323, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45503 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Burst of young retrogenes and independent retrogene formation in mammals. Pan D, et al. PLoS One, 2009. PMID 19325906, Free PMC Article
  2. Comparative genomics reveals a constant rate of origination and convergent acquisition of functional retrogenes in Drosophila. Bai Y, et al. Genome Biol, 2007. PMID 17233920, Free PMC Article
  3. Parent genes of retrotransposition-generated gene duplicates in Drosophila melanogaster have distinct expression profiles. Langille MG, et al. Genomics, 2007 Sep. PMID 17628393
  4. Nuclear chromosome dynamics in the Drosophila male germ line contribute to the nonrandom genomic distribution of retrogenes. Díaz-Castillo C, et al. Mol Biol Evol, 2012 Sep. PMID 22427708
  5. Tumour-host interactions through the lens of Drosophila. Bilder D, et al. Nat Rev Cancer, 2021 Nov. PMID 34389815, Free PMC Article

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables sequence-specific DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in positive regulation of cell growth ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in regulation of barbed-end actin filament capping IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytosol ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG7423-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    19082609..19083290 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_133119.3 → NP_573347.1  uncharacterized protein Dmel_CG7423 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_573347.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VWM3
    Related
    FBpp0074473
    Conserved Domains (3) summary
    cd00204
    Location:12 → 121
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:10 → 96
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:37 → 69
    ANK; ANK repeat [structural motif]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VWM3 Q9VWM3

Gene LinkOut

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