These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in this
section to the one reported in Genomic regions, transcripts, and products above.
Genomic
-
NG_031846.1 RefSeqGene
- Range
- 5001..16299
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001207042.2 → NP_001193971.1 protein arginine N-methyltransferase 1 isoform 4
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) lacks three exons in the coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (4) is shorter than isoform 1.
- Source sequence(s)
-
AI193116, BX352789, DC421815
- Conserved Domains (1) summary
-
- cl12011
Location:70 – 120
Blast Score: 109
- AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy)....
-
NM_001536.5 → NP_001527.3 protein arginine N-methyltransferase 1 isoform 1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes the longest isoform (1).
- Source sequence(s)
-
AI193116, AK304660, DC421815, Y10806
- Consensus CDS
-
CCDS46145.1
- UniProtKB/TrEMBL
-
B4E3C3
- UniProtKB/TrEMBL
-
H7C2I1
- UniProtKB/Swiss-Prot
-
Q99873
- Related
- ENSP00000406162, OTTHUMP00000236178, ENST00000454376, OTTHUMT00000395070
- Conserved Domains (1) summary
-
- cd02440
Location:92 – 192
Blast Score: 114
- AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy)....
-
NM_198318.4 → NP_938074.2 protein arginine N-methyltransferase 1 isoform 3
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) lacks an exon in the coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (3) is shorter than isoform 1.
- Source sequence(s)
-
AI193116, DC421815, Y10807
- Consensus CDS
-
CCDS42592.1
- UniProtKB/TrEMBL
-
G5E9B6
- UniProtKB/TrEMBL
-
Q8WUW5
- UniProtKB/Swiss-Prot
-
Q99873
- Related
- ENSP00000375724, OTTHUMP00000236176, ENST00000391851, OTTHUMT00000395065
- Conserved Domains (1) summary
-
- cd02440
Location:74 – 174
Blast Score: 113
- AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
RNA
-
NR_033397.4 RNA Sequence
- Description
- Transcript Variant: This variant (2) contains an alternate internal exon compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AI193116, CN264743, CR407608, DC421815
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs
for chromosomes and scaffolds (contigs) from both reference and alternate assemblies.
Model RNAs and proteins are also reported here.
Reference GRCh37.p5 Primary Assembly
Genomic
-
NC_000019.9 Reference GRCh37.p5 Primary Assembly
- Range
- 50180409..50191704
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate HuRef
Genomic
-
AC_000151.1 Alternate HuRef
- Range
- 46557181..46568348
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
The following Reference Sequences have been suppressed. Explain
These RefSeqs were suppressed for the cited
reason(s). Suppressed RefSeqs do not appear in BLAST databases, related sequence links,
or BLAST links (BLink), but may still be retrieved by clicking on their
accession.version below.
-
NM_198319.2: Suppressed sequence
- Description
- NM_198319.2: This RefSeq was permanently suppressed because it contains a uORF at nt 43..240 that is predicted to inhibit translation of the annotated CDS.