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    Sep4 Septin 4 [ Drosophila melanogaster ]

    Gene ID: 32646, updated on 9-May-2012
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    Summary

    Official Symbol
    Sep4provided by Flybase
    Official Full Name
    Septin 4provided by Flybase
    Primary source
    FLYBASE:FBgn0259923
    Locus tag
    Dmel_CG9699
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG9699; Dmel\CG9699; sep4
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    Genomic context

    Location :
    15A1-15A2
    Sequence :
    Chromosome: X; NC_004354.3 (16578244..16589206, complement)
    See Sep4 in Epigenomics, MapViewer

    Chromosome X - NC_004354.3Genomic Context describing neighboring genes Neighboring gene CG13010 gene product from transcript CG13010-RA Neighboring gene singles bar Neighboring gene Abnormal X segregation Neighboring gene CG4678 gene product from transcript CG4678-RE Neighboring gene CG9675 gene product from transcript CG9675-RA Neighboring gene CG9676 gene product from transcript CG9676-RA

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Vector and parameters for targeted transgenic RNA interference in Drosophila melanogaster. Ni JQ, et al. Nat Methods, 2008 Jan. PMID 18084299.
    2. Overexpression of Septin 4, the Drosophila homologue of human CDCrel-1, is toxic for dopaminergic neurons. Muñoz-Soriano V, et al. Eur J Neurosci, 2007 Dec. PMID 18028112.
    3. Sequence finishing and mapping of Drosophila melanogaster heterochromatin. Hoskins RA, et al. Science, 2007 Jun 15. PMID 17569867.
    4. The Release 5.1 annotation of Drosophila melanogaster heterochromatin. Smith CD, et al. Science, 2007 Jun 15. PMID 17569856.
    5. Spitz from the retina regulates genes transcribed in the second mitotic wave, peripodial epithelium, glia and plasmatocytes of the Drosophila eye imaginal disc. Firth LC, et al. Dev Biol, 2007 Jul 15. PMID 17553483.

    See all (19) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:58982 BioGRID:69246 Ady43A    BioGRID  PubMed Two-hybrid 
    BioGRID:58982 BioGRID:66729 Droj2    BioGRID  PubMed Two-hybrid 
    BioGRID:58982 BioGRID:65444 Grasp65    BioGRID  PubMed Two-hybrid 
    BioGRID:58982 BioGRID:71956 Mbs    BioGRID  PubMed Two-hybrid 
    BioGRID:58982 BioGRID:68254 Or98b    BioGRID  PubMed Two-hybrid 
    BioGRID:58982 BioGRID:67416 Sep2    BioGRID  PubMed Two-hybrid 
    BioGRID:58982 BioGRID:68427 Sry-alpha    BioGRID  PubMed Two-hybrid 
    BioGRID:58982 BioGRID:64396 Zasp66    BioGRID  PubMed Two-hybrid 
    BioGRID:58982 BioGRID:60700 vir-1    BioGRID  PubMed Two-hybrid 
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    General gene information

    Homology

    • Homologs of the Sep4 gene: The Sep4 gene is conserved in human, chimpanzee, , dog, cow, mouse, rat, chicken, zebrafish, mosquito, S.cerevisiae, K.lactis, , S.pombe, , and N.crassa.

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    GTPase activity NAS
    Non-traceable Author Statement
    more info
    		  
    Process Evidence Code Pubs
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		  
    cytokinesis ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    cytokinesis NAS
    Non-traceable Author Statement
    more info
    		  
    Component Evidence Code Pubs
    septin complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    septin ring ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
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    General protein information

    Preferred Names
    CG9699 gene product from transcript CG9699-RA
    Names
    CG9699-PA
    CG9699-PB
    CG9699-PC
    CG9699-PD
    CG9699-PE
    CG9699-PF
    CG9699-PG
    Sep4-PA
    Sep4-PB
    Sep4-PC
    Sep4-PD
    Sep4-PE
    Sep4-PF
    Sep4-PG
    septin
    septin 4
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.3

      Range
      16578244..16589206, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_167530.1 → NP_728003.1  septin 4, isoform A [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0KHR7
      Related
      FBpp0074139, FBtr0074365
      Conserved Domains (2) summary
      pfam00735
      Location:82 – 354
      Blast Score: 1045
      Septin; Septin
      cd01850
      Location:82 – 357
      Blast Score: 1089
      CDC_Septin; CDC/Septin GTPase family

    2. NM_167534.1 → NP_728007.1  septin 4, isoform F [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0KHR7
      Related
      FBpp0074140, FBtr0074366
      Conserved Domains (2) summary
      pfam00735
      Location:82 – 354
      Blast Score: 1045
      Septin; Septin
      cd01850
      Location:82 – 357
      Blast Score: 1089
      CDC_Septin; CDC/Septin GTPase family

    3. NM_167531.1 → NP_728004.1  septin 4, isoform B [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0KHR7
      Related
      FBpp0074141, FBtr0074367
      Conserved Domains (2) summary
      pfam00735
      Location:82 – 354
      Blast Score: 1045
      Septin; Septin
      cd01850
      Location:82 – 357
      Blast Score: 1089
      CDC_Septin; CDC/Septin GTPase family

    4. NM_167533.1 → NP_728006.1  septin 4, isoform E [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0KHR7
      Related
      FBpp0074143, FBtr0074369
      Conserved Domains (2) summary
      pfam00735
      Location:82 – 354
      Blast Score: 1045
      Septin; Septin
      cd01850
      Location:82 – 357
      Blast Score: 1089
      CDC_Septin; CDC/Septin GTPase family

    5. NM_167532.1 → NP_728005.1  septin 4, isoform D [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0KHR7
      Related
      FBpp0074142, FBtr0074368
      Conserved Domains (2) summary
      pfam00735
      Location:82 – 354
      Blast Score: 1045
      Septin; Septin
      cd01850
      Location:82 – 357
      Blast Score: 1089
      CDC_Septin; CDC/Septin GTPase family

    6. NM_132919.2 → NP_573147.2  septin 4, isoform C [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0KHR7
      Related
      FBpp0074144, FBtr0074370
      Conserved Domains (2) summary
      pfam00735
      Location:82 – 354
      Blast Score: 1045
      Septin; Septin
      cd01850
      Location:82 – 357
      Blast Score: 1089
      CDC_Septin; CDC/Septin GTPase family

    7. NM_206766.1 → NP_996489.1  septin 4, isoform G [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7KUX3
      Related
      FBpp0074145, FBtr0074371
      Conserved Domains (2) summary
      pfam00735
      Location:30 – 302
      Blast Score: 1031
      Septin; Septin
      cd01850
      Location:30 – 305
      Blast Score: 1075
      CDC_Septin; CDC/Septin GTPase family
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AE014298.4 AAN09416.1
    genomic AE014298.4 AAN09415.1
    genomic AE014298.4 AAN09414.1
    genomic AE014298.4 AAN09417.1
    genomic AE014298.4 AAF48646.1
    genomic AE014298.4 AAF48645.1
    genomic AE014298.4 AAS65390.1
    mRNA BT132948.1 AEW43888.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VXD0.1 GenPept
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    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

      Supplemental Content