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CG31689 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 326154, updated on 8-Apr-2024

Summary

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Official Symbol
CG31689provided by FlyBase
Primary source
FLYBASE:FBgn0031449
Locus tag
Dmel_CG31689
See related
AllianceGenome:FB:FBgn0031449
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG9892; DmCG31689; Dmel\CG31689
Summary
Predicted to enable ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be active in plasma membrane. Is expressed in several structures, including adult head; hindgut proper primordium; and presumptive embryonic/larval digestive system. Orthologous to human ABCG4 (ATP binding cassette subfamily G member 4). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
23A3-23A3; 2-7 cM
Exon count:
14
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (2725674..2739830)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (2725674..2739830)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Gustatory receptor 23a Neighboring gene Transmembrane O-mannosyltransferase targeting cadherins 1 Neighboring gene TBP-related factor 5 Neighboring gene mir-4914 stem loop Neighboring gene uncharacterized protein Neighboring gene Hepatocyte growth factor regulated tyrosine kinase substrate Neighboring gene Cwc25 Neighboring gene Phosphoglycerate kinase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The polarity protein Dlg5 regulates collective cell migration during Drosophila oogenesis. Luo J, et al. PLoS One, 2019. PMID 31856229, Free PMC Article
  2. Musashi expression in intestinal stem cells attenuates radiation-induced decline in intestinal permeability and survival in Drosophila. Sharma A, et al. Sci Rep, 2020 Nov 5. PMID 33154387, Free PMC Article
  3. Characterization of a novel pesticide transporter and P-glycoprotein orthologues in Drosophila melanogaster. Denecke S, et al. Proc Biol Sci, 2022 May 25. PMID 35582794, Free PMC Article
  4. Transcriptional regulation by CHIP/LDB complexes. Bronstein R, et al. PLoS Genet, 2010 Aug 12. PMID 20730086, Free PMC Article
  5. A genome-wide RNAi screen identifies MASK as a positive regulator of cytokine receptor stability. Fisher KH, et al. J Cell Sci, 2018 Jul 6. PMID 29848658, Free PMC Article

See all (38) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ABC-type transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables ATPase-coupled transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ATPase-coupled transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transmembrane transport ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG31689-PA
CG31689-PB
CG31689-PC
CG31689-PD
CG31689-PE
CG31689-PF
CG31689-PG
CG31689-PH
NP_001259951.1
NP_001259952.1
NP_001259953.1
NP_001259954.1
NP_608703.2
NP_722827.1
NP_722828.1
NP_722829.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    2725674..2739830
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001273025.1 → NP_001259954.1  uncharacterized protein Dmel_CG31689, isoform H [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259954.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PBX3, Q8T998
    Conserved Domains (3) summary
    cd03213
    Location:26 → 239
    ABCG_EPDR; Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily
    TIGR00955
    Location:15 → 622
    3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein
    pfam01061
    Location:355 → 558
    ABC2_membrane; ABC-2 type transporter

  2. NM_164495.2 → NP_722829.1  uncharacterized protein Dmel_CG31689, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_722829.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T998, Q9VQF1
    Related
    FBpp0077390
    Conserved Domains (3) summary
    cd03213
    Location:12 → 230
    ABCG_EPDR; Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily
    TIGR00955
    Location:28 → 613
    3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein
    pfam01061
    Location:346 → 549
    ABC2_membrane; ABC-2 type transporter

  3. NM_164493.2 → NP_722827.1  uncharacterized protein Dmel_CG31689, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_722827.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T998, Q9VQF1
    Related
    FBpp0077391
    Conserved Domains (3) summary
    cd03213
    Location:12 → 230
    ABCG_EPDR; Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily
    TIGR00955
    Location:28 → 613
    3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein
    pfam01061
    Location:346 → 549
    ABC2_membrane; ABC-2 type transporter

  4. NM_134859.3 → NP_608703.2  uncharacterized protein Dmel_CG31689, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_608703.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T998, Q9VQF1
    Related
    FBpp0077389
    Conserved Domains (3) summary
    cd03213
    Location:12 → 230
    ABCG_EPDR; Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily
    TIGR00955
    Location:28 → 613
    3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein
    pfam01061
    Location:346 → 549
    ABC2_membrane; ABC-2 type transporter

  5. NM_001273023.1 → NP_001259952.1  uncharacterized protein Dmel_CG31689, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259952.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T998, Q9VQF1
    Conserved Domains (3) summary
    cd03213
    Location:12 → 230
    ABCG_EPDR; Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily
    TIGR00955
    Location:28 → 613
    3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein
    pfam01061
    Location:346 → 549
    ABC2_membrane; ABC-2 type transporter

  6. NM_164494.2 → NP_722828.1  uncharacterized protein Dmel_CG31689, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_722828.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T998, Q9VQF1
    Related
    FBpp0077392
    Conserved Domains (3) summary
    cd03213
    Location:12 → 230
    ABCG_EPDR; Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily
    TIGR00955
    Location:28 → 613
    3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein
    pfam01061
    Location:346 → 549
    ABC2_membrane; ABC-2 type transporter

  7. NM_001273022.1 → NP_001259951.1  uncharacterized protein Dmel_CG31689, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259951.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T998, Q9VQF1
    Conserved Domains (3) summary
    cd03213
    Location:12 → 230
    ABCG_EPDR; Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily
    TIGR00955
    Location:28 → 613
    3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein
    pfam01061
    Location:346 → 549
    ABC2_membrane; ABC-2 type transporter

  8. NM_001273024.1 → NP_001259953.1  uncharacterized protein Dmel_CG31689, isoform G [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259953.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T998, Q9VQF1
    Conserved Domains (3) summary
    cd03213
    Location:12 → 230
    ABCG_EPDR; Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily
    TIGR00955
    Location:28 → 613
    3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein
    pfam01061
    Location:346 → 549
    ABC2_membrane; ABC-2 type transporter
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
M9PBX3 M9PBX3
Q8T998 Q8T998
Q9VQF1 Q9VQF1

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