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HDAC4 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32278, updated on 3-May-2015
Official Symbol
HDAC4provided by FlyBase
Primary source
FLYBASE:FBgn0041210
Locus tag
Dmel_CG1770
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG1770; dHDAC4; DHDAC4; Dmel\CG1770; dmHDA405; GC1770; HDAC; hdac4; HDAC4a
See HDAC4 in MapViewer
Location:
11E8-11E9
Exon count:
16
Annotation release Status Assembly Chr Location
Release 6.01 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (13262687..13285632, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (13156720..13179665, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene multiple edematous wings Neighboring gene CG15742 gene product from transcript CG15742-RC Neighboring gene comatose Neighboring gene CG15743 gene product from transcript CG15743-RC Neighboring gene CG15744 gene product from transcript CG15744-RA

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • Cell cycle, organism-specific biosystem (from WikiPathways)
    Cell cycle, organism-specific biosystem(From http://en.wikipedia.org/wiki/Cell_cycle) The cell cycle is the series of events that takes place in a cell leading to its division and duplication (replication). Regulation of the cell cycle in...
Products Interactant Other Gene Complex Source Pubs Description

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
histone deacetylase activity IDA
Inferred from Direct Assay
more info
PubMed 
histone deacetylase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
histone deacetylase activity NAS
Non-traceable Author Statement
more info
 
Process Evidence Code Pubs
long-term memory IMP
Inferred from Mutant Phenotype
more info
PubMed 
memory IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of transcription, DNA-templated IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
CG1770 gene product from transcript CG1770-RG
Names
CG1770-PB
CG1770-PD
CG1770-PE
CG1770-PF
CG1770-PG
CG1770-PH
CG1770-PI
CG1770-PJ
HDAC4
HDAC4-PB
HDAC4-PD
HDAC4-PE
HDAC4-PF
HDAC4-PG
HDAC4-PH
HDAC4-PI
HDAC4-PJ
NP_001014736.2
NP_001245651.1
NP_001259507.1
NP_001259508.1
NP_001259509.1
NP_001259510.1
NP_572868.3
NP_727682.1

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    13262687..13285632
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001272578.2NP_001259507.1  HDAC4, isoform G [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259507.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PHQ2
    Related
    FBpp0305523, FBtr0333331
    Conserved Domains (2) summary
    cd11681
    Location:8371211
    HDAC_classIIa; Histone deacetylases, class IIa
    cl13614
    Location:4387
    ClassIIa_HDAC_Gln-rich-N; Glutamine-rich N-terminal helical domain of various Class IIa histone deacetylases (HDAC4, HDAC5 and HDCA9)
  2. NM_001272581.2NP_001259510.1  HDAC4, isoform J [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259510.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PJM2
    Related
    FBpp0305526, FBtr0333334
    Conserved Domains (2) summary
    cd11681
    Location:7731147
    HDAC_classIIa; Histone deacetylases, class IIa
    cl13614
    Location:350
    ClassIIa_HDAC_Gln-rich-N; Glutamine-rich N-terminal helical domain of various Class IIa histone deacetylases (HDAC4, HDAC5 and HDCA9)
  3. NM_132640.6NP_572868.3  HDAC4, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572868.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VYF3
    Related
    FBpp0290513, FBtr0301298
    Conserved Domains (2) summary
    cd11681
    Location:8201194
    HDAC_classIIa; Histone deacetylases, class IIa
    cl13614
    Location:4397
    ClassIIa_HDAC_Gln-rich-N; Glutamine-rich N-terminal helical domain of various Class IIa histone deacetylases (HDAC4, HDAC5 and HDCA9)
  4. NM_001272580.2NP_001259509.1  HDAC4, isoform I [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259509.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PJM2
    Related
    FBpp0305525, FBtr0333333
    Conserved Domains (2) summary
    cd11681
    Location:7731147
    HDAC_classIIa; Histone deacetylases, class IIa
    cl13614
    Location:350
    ClassIIa_HDAC_Gln-rich-N; Glutamine-rich N-terminal helical domain of various Class IIa histone deacetylases (HDAC4, HDAC5 and HDCA9)
  5. NM_001272579.2NP_001259508.1  HDAC4, isoform H [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259508.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8IR69
    Related
    FBpp0305524, FBtr0333332
    Conserved Domains (1) summary
    cd11681
    Location:7491123
    HDAC_classIIa; Histone deacetylases, class IIa
  6. NM_001014736.5NP_001014736.2  HDAC4, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001014736.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q59E49
    Related
    FBpp0290514, FBtr0301299
    Conserved Domains (2) summary
    cd11681
    Location:7711145
    HDAC_classIIa; Histone deacetylases, class IIa
    cl13614
    Location:4397
    ClassIIa_HDAC_Gln-rich-N; Glutamine-rich N-terminal helical domain of various Class IIa histone deacetylases (HDAC4, HDAC5 and HDCA9)
  7. NM_001258722.3NP_001245651.1  HDAC4, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001245651.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9NEF2
    Related
    FBpp0300800, FBtr0308576
    Conserved Domains (2) summary
    cd11681
    Location:8101184
    HDAC_classIIa; Histone deacetylases, class IIa
    cl13614
    Location:4386
    ClassIIa_HDAC_Gln-rich-N; Glutamine-rich N-terminal helical domain of various Class IIa histone deacetylases (HDAC4, HDAC5 and HDCA9)
  8. NM_167356.3NP_727682.1  HDAC4, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_727682.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8IR69
    Related
    FBpp0073629, FBtr0073798
    Conserved Domains (1) summary
    cd11681
    Location:7491123
    HDAC_classIIa; Histone deacetylases, class IIa