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    p115 [ Drosophila melanogaster ]

    Gene ID: 31698, updated on 10-May-2012
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    Summary

    Official Symbol
    p115provided by Flybase
    Primary source
    FLYBASE:FBgn0040087
    Locus tag
    Dmel_CG1422
    Gene type
    protein coding
    RNA name
    p115
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG1422; Dmel\CG1422; dp115; l(1)G0306
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    Genomic context

    Location :
    7C2-7C2
    Sequence :
    Chromosome: X; NC_004354.3 (7788070..7790819)
    See p115 in Epigenomics, MapViewer

    Chromosome X - NC_004354.3Genomic Context describing neighboring genes Neighboring gene CG17256 gene product from transcript CG17256-RA Neighboring gene CG18624 gene product from transcript CG18624-RC Neighboring gene pseudo Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene Ribosomal protein S6

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Proteomics approach to study the functions of Drosophila myosin VI through identification of multiple cargo-binding proteins. Finan D, et al. Proc Natl Acad Sci U S A, 2011 Apr 5. PMID 21368190.
    2. Conserved genes act as modifiers of invertebrate SMN loss of function defects. Dimitriadi M, et al. PLoS Genet, 2010 Oct 28. PMID 21124729.
    3. Golgi coiled-coil proteins contain multiple binding sites for Rab family G proteins. Sinka R, et al. J Cell Biol, 2008 Nov 17. PMID 19001129.
    4. Modeling spinal muscular atrophy in Drosophila. Chang HC, et al. PLoS One, 2008 Sep 15. PMID 18791638.
    5. Sequence finishing and mapping of Drosophila melanogaster heterochromatin. Hoskins RA, et al. Science, 2007 Jun 15. PMID 17569867.

    See all (20) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. Depletion of p115 by RNAi in Drosophila S2 cells led to important morphological changes in the Golgi apparatus and the transitional ER.
      Title: A novel role for dp115 in the organization of tER sites in Drosophila.
    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:58172 BioGRID:68328 Brd8    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:64968 CG13458    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:60007 CG13996    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:58095 CG14442    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:62860 CG15109    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:62243 CG17050    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:67176 CG17801    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:57754 CG2865    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:68397 CG31036    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:68394 CG31038    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:66561 CG31211    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:77425 CG31917    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:59866 CG3294    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:624762 CG34383    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:62572 CG5089    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:64646 CG6163    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:65440 CG7757    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:60319 CG9463    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:60332 CG9541    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:65565 CSN3    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:61621 CSN4    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:64171 D19A    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:57637 DAAM    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:58239 Es2    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:63144 GM130    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:62712 HLH54F    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:64660 Mob2    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:63381 PHDP    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:66344 Pnn    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:59718 Rbp9    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:67795 Tsc1    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:67224 WRNexo    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:67862 ash2    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:59332 cactin    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:64252 eco    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:72789 esn    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:57548 ewg    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:64769 eyg    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:64323 ldbr    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:60490 lft    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:63677 mwh    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:65884 noi    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:59390 pen    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:62296 shot    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:60129 sip2    BioGRID  PubMed Two-hybrid 
    BioGRID:58172 BioGRID:58695 tth    BioGRID  PubMed Two-hybrid 
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    General gene information

    Homology

    • Homologs of the p115 gene: The p115 gene is conserved in human, chimpanzee, , dog, cow, mouse, rat, chicken, zebrafish, mosquito, C.elegans, , , N.crassa, A.thaliana, and rice.

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    protein transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    Golgi organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    vesicle docking involved in exocytosis ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    vesicle fusion with Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    Golgi stack IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
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    General protein information

    Preferred Names
    CG1422 gene product from transcript CG1422-RA
    Names
    CG1422-PA
    p115
    p115-PA
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.3

      Range
      7788070..7790819
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132189.2 → NP_572417.1  p115 [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W3N6
      Related
      FBpp0071045, FBtr0071089
      Conserved Domains (4) summary
      pfam04871
      Location:686 – 816
      Blast Score: 156
      Uso1_p115_C; Uso1 / p115 like vesicle tethering protein, C terminal region
      pfam04869
      Location:348 – 634
      Blast Score: 774
      Uso1_p115_head; Uso1 / p115 like vesicle tethering protein, head region
      pfam12717
      Location:138 – 203
      Blast Score: 94
      Cnd1; non-SMC mitotic condensation complex subunit 1
      cl02500
      Location:24 – 98
      Blast Score: 85
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AE014298.4 AAF46286.2
    mRNA AY058751.1 AAL13980.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W3N6.1 GenPept
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    Additional Links

    Gene LinkOut

      Supplemental Content