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Mlph melanophilin [ Rattus norvegicus (Norway rat) ]

Gene ID: 316620, updated on 1-Aug-2015
Official Symbol
Mlphprovided by RGD
Official Full Name
melanophilinprovided by RGD
Primary source
RGD:1310733
See related
Ensembl:ENSRNOG00000019763; Vega:OTTRNOG00000001356
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
Orthologs
See Mlph in MapViewer
Location:
9q36
Exon count:
16
Annotation release Status Assembly Chr Location
105 current Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (98072838..98108429)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 9 NC_005108.3 (97753726..97789586)

Chromosome 9 - NC_005108.4Genomic Context describing neighboring genes Neighboring gene COP9 signalosome subunit 8 Neighboring gene collagen, type VI, alpha 3 Neighboring gene prolactin releasing hormone Neighboring gene RAB17, member RAS oncogene family

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
Rab GTPase binding IEA
Inferred from Electronic Annotation
more info
 
Rab GTPase binding ISO
Inferred from Sequence Orthology
more info
 
actin binding ISO
Inferred from Sequence Orthology
more info
 
microtubule plus-end binding ISO
Inferred from Sequence Orthology
more info
 
myosin V binding ISO
Inferred from Sequence Orthology
more info
 
myosin binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
intracellular protein transport IEA
Inferred from Electronic Annotation
more info
 
melanocyte differentiation ISO
Inferred from Sequence Orthology
more info
 
melanosome localization ISO
Inferred from Sequence Orthology
more info
 
pigmentation ISO
Inferred from Sequence Orthology
more info
 
protein targeting ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
actin cytoskeleton ISO
Inferred from Sequence Orthology
more info
 
cell ISO
Inferred from Sequence Orthology
more info
 
cortical actin cytoskeleton ISO
Inferred from Sequence Orthology
more info
 
dendrite IEA
Inferred from Electronic Annotation
more info
 
dendrite ISO
Inferred from Sequence Orthology
more info
 
extracellular exosome IEA
Inferred from Electronic Annotation
more info
 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
intracellular ISO
Inferred from Sequence Orthology
more info
 
melanosome ISO
Inferred from Sequence Orthology
more info
 
microtubule organizing center ISO
Inferred from Sequence Orthology
more info
 
colocalizes_with microtubule plus-end ISO
Inferred from Sequence Orthology
more info
 
perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
 
perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
 
stress fiber ISO
Inferred from Sequence Orthology
more info
 

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012135.1NP_001012135.1  melanophilin

    See identical proteins and their annotated locations for NP_001012135.1

    Status: PROVISIONAL

    Source sequence(s)
    BC081894
    UniProtKB/TrEMBL
    G3V8M0
    Related
    ENSRNOP00000026795, OTTRNOP00000001221, ENSRNOT00000026795, OTTRNOT00000002083
    Conserved Domains (2) summary
    pfam04698
    Location:307576
    Rab_eff_C; Rab effector MyRIP/melanophilin C-terminus
    cd15752
    Location:62137
    FYVE_SlaC2-a; FYVE-related domain found in Slp homolog lacking C2 domains a (SlaC2-a) and similar proteins

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 105

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005108.4 Reference Rnor_6.0 Primary Assembly

    Range
    98072838..98108429
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006245405.2XP_006245467.1  

    Conserved Domains (2) summary
    pfam04698
    Location:394526
    Rab_eff_C; Rab effector MyRIP/melanophilin C-terminus
    cd15752
    Location:62137
    FYVE_SlaC2-a; FYVE-related domain found in Slp homolog lacking C2 domains a (SlaC2-a) and similar proteins
  2. XM_006245404.2XP_006245466.1  

    See identical proteins and their annotated locations for XP_006245466.1

    Conserved Domains (2) summary
    pfam04698
    Location:308577
    Rab_eff_C; Rab effector MyRIP/melanophilin C-terminus
    cd15752
    Location:62137
    FYVE_SlaC2-a; FYVE-related domain found in Slp homolog lacking C2 domains a (SlaC2-a) and similar proteins

Alternate Rn_Celera

Genomic

  1. AC_000077.1 Alternate Rn_Celera

    Range
    89051850..89087296
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)